These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

349 related articles for article (PubMed ID: 31521506)

  • 1. Non-core Subunits of the PRC2 Complex Are Collectively Required for Its Target-Site Specificity.
    Højfeldt JW; Hedehus L; Laugesen A; Tatar T; Wiehle L; Helin K
    Mol Cell; 2019 Nov; 76(3):423-436.e3. PubMed ID: 31521506
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The H3K36me2 Methyltransferase Nsd1 Demarcates PRC2-Mediated H3K27me2 and H3K27me3 Domains in Embryonic Stem Cells.
    Streubel G; Watson A; Jammula SG; Scelfo A; Fitzpatrick DJ; Oliviero G; McCole R; Conway E; Glancy E; Negri GL; Dillon E; Wynne K; Pasini D; Krogan NJ; Bracken AP; Cagney G
    Mol Cell; 2018 Apr; 70(2):371-379.e5. PubMed ID: 29606589
    [TBL] [Abstract][Full Text] [Related]  

  • 3. PRC2.1 and PRC2.2 Synergize to Coordinate H3K27 Trimethylation.
    Healy E; Mucha M; Glancy E; Fitzpatrick DJ; Conway E; Neikes HK; Monger C; Van Mierlo G; Baltissen MP; Koseki Y; Vermeulen M; Koseki H; Bracken AP
    Mol Cell; 2019 Nov; 76(3):437-452.e6. PubMed ID: 31521505
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Dissecting the role of H3K27 acetylation and methylation in PRC2 mediated control of cellular identity.
    Lavarone E; Barbieri CM; Pasini D
    Nat Commun; 2019 Apr; 10(1):1679. PubMed ID: 30976011
    [TBL] [Abstract][Full Text] [Related]  

  • 5. A Dimeric Structural Scaffold for PRC2-PCL Targeting to CpG Island Chromatin.
    Chen S; Jiao L; Liu X; Yang X; Liu X
    Mol Cell; 2020 Mar; 77(6):1265-1278.e7. PubMed ID: 31959557
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Identification of a PRC2 Accessory Subunit Required for Subtelomeric H3K27 Methylation in Neurospora crassa.
    McNaught KJ; Wiles ET; Selker EU
    Mol Cell Biol; 2020 May; 40(11):. PubMed ID: 32179551
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Full methylation of H3K27 by PRC2 is dispensable for initial embryoid body formation but required to maintain differentiated cell identity.
    Miller SA; Damle M; Kim J; Kingston RE
    Development; 2021 Apr; 148(7):. PubMed ID: 33688077
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Molecular Mechanisms Directing PRC2 Recruitment and H3K27 Methylation.
    Laugesen A; Højfeldt JW; Helin K
    Mol Cell; 2019 Apr; 74(1):8-18. PubMed ID: 30951652
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Accurate H3K27 methylation can be established de novo by SUZ12-directed PRC2.
    Højfeldt JW; Laugesen A; Willumsen BM; Damhofer H; Hedehus L; Tvardovskiy A; Mohammad F; Jensen ON; Helin K
    Nat Struct Mol Biol; 2018 Mar; 25(3):225-232. PubMed ID: 29483650
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Two Functional Axes of Feedback-Enforced PRC2 Recruitment in Mouse Embryonic Stem Cells.
    Perino M; van Mierlo G; Loh C; Wardle SMT; Zijlmans DW; Marks H; Veenstra GJC
    Stem Cell Reports; 2020 Dec; 15(6):1287-1300. PubMed ID: 32763159
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Polycomb Repressive Complex 2 Methylates Elongin A to Regulate Transcription.
    Ardehali MB; Anselmo A; Cochrane JC; Kundu S; Sadreyev RI; Kingston RE
    Mol Cell; 2017 Dec; 68(5):872-884.e6. PubMed ID: 29153392
    [TBL] [Abstract][Full Text] [Related]  

  • 12. EZH2 variants differentially regulate polycomb repressive complex 2 in histone methylation and cell differentiation.
    Mu W; Starmer J; Yee D; Magnuson T
    Epigenetics Chromatin; 2018 Dec; 11(1):71. PubMed ID: 30522506
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Integrative Proteomic Profiling Reveals PRC2-Dependent Epigenetic Crosstalk Maintains Ground-State Pluripotency.
    van Mierlo G; Dirks RAM; De Clerck L; Brinkman AB; Huth M; Kloet SL; Saksouk N; Kroeze LI; Willems S; Farlik M; Bock C; Jansen JH; Deforce D; Vermeulen M; Déjardin J; Dhaenens M; Marks H
    Cell Stem Cell; 2019 Jan; 24(1):123-137.e8. PubMed ID: 30472157
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Automethylation of PRC2 promotes H3K27 methylation and is impaired in H3K27M pediatric glioma.
    Lee CH; Yu JR; Granat J; Saldaña-Meyer R; Andrade J; LeRoy G; Jin Y; Lund P; Stafford JM; Garcia BA; Ueberheide B; Reinberg D
    Genes Dev; 2019 Oct; 33(19-20):1428-1440. PubMed ID: 31488577
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Capturing the Onset of PRC2-Mediated Repressive Domain Formation.
    Oksuz O; Narendra V; Lee CH; Descostes N; LeRoy G; Raviram R; Blumenberg L; Karch K; Rocha PP; Garcia BA; Skok JA; Reinberg D
    Mol Cell; 2018 Jun; 70(6):1149-1162.e5. PubMed ID: 29932905
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Polycomb-mediated genome architecture enables long-range spreading of H3K27 methylation.
    Kraft K; Yost KE; Murphy SE; Magg A; Long Y; Corces MR; Granja JM; Wittler L; Mundlos S; Cech TR; Boettiger AN; Chang HY
    Proc Natl Acad Sci U S A; 2022 May; 119(22):e2201883119. PubMed ID: 35617427
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Morphine leads to global genome changes in H3K27me3 levels via a Polycomb Repressive Complex 2 (PRC2) self-regulatory mechanism in mESCs.
    Muñoa-Hoyos I; Halsall JA; Araolaza M; Ward C; Garcia I; Urizar-Arenaza I; Gianzo M; Garcia P; Turner B; Subirán N
    Clin Epigenetics; 2020 Nov; 12(1):170. PubMed ID: 33168052
    [TBL] [Abstract][Full Text] [Related]  

  • 18. H2A Ubiquitination Alters H3-tail Dynamics on Linker-DNA to Enhance H3K27 Methylation.
    Ohtomo H; Ito S; McKenzie NJ; Uckelmann M; Wakamori M; Ehara H; Furukawa A; Tsunaka Y; Shibata M; Sekine SI; Umehara T; Davidovich C; Koseki H; Nishimura Y
    J Mol Biol; 2023 Feb; 435(4):167936. PubMed ID: 36610636
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Structural basis for PRC2 engagement with chromatin.
    Glancy E; Ciferri C; Bracken AP
    Curr Opin Struct Biol; 2021 Apr; 67():135-144. PubMed ID: 33232890
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Small Molecule Approaches for Targeting the Polycomb Repressive Complex 2 (PRC2) in Cancer.
    Martin MC; Zeng G; Yu J; Schiltz GE
    J Med Chem; 2020 Dec; 63(24):15344-15370. PubMed ID: 33283516
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 18.