BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

190 related articles for article (PubMed ID: 31525064)

  • 1. Quantitative Translation of Microfluidic Transporter
    van der Made TK; Fedecostante M; Scotcher D; Rostami-Hodjegan A; Sastre Toraño J; Middel I; Koster AS; Gerritsen KG; Jankowski V; Jankowski J; Hoenderop JGJ; Masereeuw R; Galetin A
    Mol Pharm; 2019 Nov; 16(11):4551-4562. PubMed ID: 31525064
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The Influence of OAT1 Density and Functionality on Indoxyl Sulfate Transport in the Human Proximal Tubule: An Integrated Computational and In Vitro Study.
    King J; Mihaila SM; Ahmed S; Truckenmüller R; Giselbrecht S; Masereeuw R; Carlier A
    Toxins (Basel); 2021 Sep; 13(10):. PubMed ID: 34678967
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Interactions of human organic anion as well as cation transporters with indoxyl sulfate.
    Enomoto A; Takeda M; Taki K; Takayama F; Noshiro R; Niwa T; Endou H
    Eur J Pharmacol; 2003 Apr; 466(1-2):13-20. PubMed ID: 12679137
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Identification and Quantitative Assessment of Uremic Solutes as Inhibitors of Renal Organic Anion Transporters, OAT1 and OAT3.
    Hsueh CH; Yoshida K; Zhao P; Meyer TW; Zhang L; Huang SM; Giacomini KM
    Mol Pharm; 2016 Sep; 13(9):3130-40. PubMed ID: 27467266
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Incorporating Uremic Solute-mediated Inhibition of OAT1/3 Improves PBPK Prediction of Tenofovir Renal and Systemic Disposition in Patients with Severe Kidney Disease.
    Chang SY; Huang W; Chapron A; Quiñones AJL; Wang J; Isoherranen N; Shen DD; Kelly EJ; Himmelfarb J; Yeung CK
    Pharm Res; 2023 Nov; 40(11):2597-2606. PubMed ID: 37704895
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Accumulation of indoxyl sulfate in OAT1/3-positive tubular cells in kidneys of patients with chronic renal failure.
    Taki K; Nakamura S; Miglinas M; Enomoto A; Niwa T
    J Ren Nutr; 2006 Jul; 16(3):199-203. PubMed ID: 16825019
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Bioengineered kidney tubules efficiently excrete uremic toxins.
    Jansen J; Fedecostante M; Wilmer MJ; Peters JG; Kreuser UM; van den Broek PH; Mensink RA; Boltje TJ; Stamatialis D; Wetzels JF; van den Heuvel LP; Hoenderop JG; Masereeuw R
    Sci Rep; 2016 May; 6():26715. PubMed ID: 27242131
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Interaction between two sulfate-conjugated uremic toxins, p-cresyl sulfate and indoxyl sulfate, during binding with human serum albumin.
    Watanabe H; Noguchi T; Miyamoto Y; Kadowaki D; Kotani S; Nakajima M; Miyamura S; Ishima Y; Otagiri M; Maruyama T
    Drug Metab Dispos; 2012 Jul; 40(7):1423-8. PubMed ID: 22513409
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Drugs Commonly Applied to Kidney Patients May Compromise Renal Tubular Uremic Toxins Excretion.
    Mihaila SM; Faria J; Stefens MFJ; Stamatialis D; Verhaar MC; Gerritsen KGF; Masereeuw R
    Toxins (Basel); 2020 Jun; 12(6):. PubMed ID: 32545617
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Extrapolation of In Vivo Hepatic Clearance from In Vitro Uptake Clearance by Suspended Human Hepatocytes for Anionic Drugs with High Binding to Human Albumin: Improvement of In Vitro-to-In Vivo Extrapolation by Considering the "Albumin-Mediated" Hepatic Uptake Mechanism on the Basis of the "Facilitated-Dissociation Model".
    Kim SJ; Lee KR; Miyauchi S; Sugiyama Y
    Drug Metab Dispos; 2019 Feb; 47(2):94-103. PubMed ID: 30504137
    [TBL] [Abstract][Full Text] [Related]  

  • 11. SLC22A11 Inserts the Uremic Toxins Indoxyl Sulfate and P-Cresol Sulfate into the Plasma Membrane.
    Tust M; Müller JP; Fischer D; Gründemann D
    Int J Mol Sci; 2023 Oct; 24(20):. PubMed ID: 37894870
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Key Role for the Organic Anion Transporters, OAT1 and OAT3, in the in vivo Handling of Uremic Toxins and Solutes.
    Wu W; Bush KT; Nigam SK
    Sci Rep; 2017 Jul; 7(1):4939. PubMed ID: 28694431
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Effect of Chronic Kidney Disease on the Renal Secretion via Organic Anion Transporters 1/3: Implications for Physiologically-Based Pharmacokinetic Modeling and Dose Adjustment.
    Tan SPF; Scotcher D; Rostami-Hodjegan A; Galetin A
    Clin Pharmacol Ther; 2022 Sep; 112(3):643-652. PubMed ID: 35569107
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Intestinal secretion of indoxyl sulfate as a possible compensatory excretion pathway in chronic kidney disease.
    Morimoto K; Tominaga Y; Agatsuma Y; Miyamoto M; Kashiwagura S; Takahashi A; Sano Y; Yano K; Kakinuma C; Ogihara T; Tomita M
    Biopharm Drug Dispos; 2018 Jul; 39(7):328-334. PubMed ID: 29975986
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Screening of Drug-Transporter Interactions in a 3D Microfluidic Renal Proximal Tubule on a Chip.
    Vriend J; Nieskens TTG; Vormann MK; van den Berge BT; van den Heuvel A; Russel FGM; Suter-Dick L; Lanz HL; Vulto P; Masereeuw R; Wilmer MJ
    AAPS J; 2018 Jul; 20(5):87. PubMed ID: 30051196
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Action of EGF and PGE2 on basolateral organic anion uptake in rabbit proximal renal tubules and hOAT1 expressed in human kidney epithelial cells.
    Sauvant C; Hesse D; Holzinger H; Evans KK; Dantzler WH; Gekle M
    Am J Physiol Renal Physiol; 2004 Apr; 286(4):F774-83. PubMed ID: 14644751
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Role of organic anion transporters in the tubular transport of indoxyl sulfate and the induction of its nephrotoxicity.
    Enomoto A; Takeda M; Tojo A; Sekine T; Cha SH; Khamdang S; Takayama F; Aoyama I; Nakamura S; Endou H; Niwa T
    J Am Soc Nephrol; 2002 Jul; 13(7):1711-20. PubMed ID: 12089366
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Hypouricemic agents reduce indoxyl sulfate excretion by inhibiting the renal transporters OAT1/3 and ABCG2.
    Taniguchi T; Omura K; Motoki K; Sakai M; Chikamatsu N; Ashizawa N; Takada T; Iwanaga T
    Sci Rep; 2021 Mar; 11(1):7232. PubMed ID: 33790363
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Improvement of Protein Expression Profile in Three-Dimensional Renal Proximal Tubular Epithelial Cell Spheroids Selected Based on OAT1 Gene Expression: A Potential In Vitro Tool for Evaluating Human Renal Proximal Tubular Toxicity and Drug Disposition.
    Ishiguro N; Takahashi E; Arakawa H; Saito A; Kitagawa F; Kondo M; Morinaga G; Takatani M; Takahashi R; Kudo T; Mae SI; Kadoguchi M; Higuchi D; Nakazono Y; Tamai I; Osafune K; Jimbo Y
    Drug Metab Dispos; 2023 Sep; 51(9):1177-1187. PubMed ID: 37385755
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Evolution of protein-bound uremic toxins indoxyl sulphate and p-cresyl sulphate in acute kidney injury.
    Veldeman L; Vanmassenhove J; Van Biesen W; Massy ZA; Liabeuf S; Glorieux G; Vanholder R
    Int Urol Nephrol; 2019 Feb; 51(2):293-302. PubMed ID: 30604232
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.