BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

630 related articles for article (PubMed ID: 31527908)

  • 1. Neutralization-guided design of HIV-1 envelope trimers with high affinity for the unmutated common ancestor of CH235 lineage CD4bs broadly neutralizing antibodies.
    LaBranche CC; Henderson R; Hsu A; Behrens S; Chen X; Zhou T; Wiehe K; Saunders KO; Alam SM; Bonsignori M; Borgnia MJ; Sattentau QJ; Eaton A; Greene K; Gao H; Liao HX; Williams WB; Peacock J; Tang H; Perez LG; Edwards RJ; Kepler TB; Korber BT; Kwong PD; Mascola JR; Acharya P; Haynes BF; Montefiori DC
    PLoS Pathog; 2019 Sep; 15(9):e1008026. PubMed ID: 31527908
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Murine Antibody Responses to Cleaved Soluble HIV-1 Envelope Trimers Are Highly Restricted in Specificity.
    Hu JK; Crampton JC; Cupo A; Ketas T; van Gils MJ; Sliepen K; de Taeye SW; Sok D; Ozorowski G; Deresa I; Stanfield R; Ward AB; Burton DR; Klasse PJ; Sanders RW; Moore JP; Crotty S
    J Virol; 2015 Oct; 89(20):10383-98. PubMed ID: 26246566
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Antigenicity and Immunogenicity of HIV-1 Envelope Trimers Complexed to a Small-Molecule Viral Entry Inhibitor.
    Alam SM; Cronin K; Parks R; Anasti K; Ding H; Go EP; Desaire H; Eaton A; Montefiori D; Sodroski J; Kappes J; Haynes BF; Saunders KO
    J Virol; 2020 Oct; 94(21):. PubMed ID: 32817216
    [TBL] [Abstract][Full Text] [Related]  

  • 4. HIV-1 envelope glycan modifications that permit neutralization by germline-reverted VRC01-class broadly neutralizing antibodies.
    LaBranche CC; McGuire AT; Gray MD; Behrens S; Kwong PDK; Chen X; Zhou T; Sattentau QJ; Peacock J; Eaton A; Greene K; Gao H; Tang H; Perez LG; Chen X; Saunders KO; Kwong PD; Mascola JR; Haynes BF; Stamatatos L; Montefiori DC
    PLoS Pathog; 2018 Nov; 14(11):e1007431. PubMed ID: 30395637
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Well-ordered trimeric HIV-1 subtype B and C soluble spike mimetics generated by negative selection display native-like properties.
    Guenaga J; de Val N; Tran K; Feng Y; Satchwell K; Ward AB; Wyatt RT
    PLoS Pathog; 2015 Jan; 11(1):e1004570. PubMed ID: 25569572
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Improving the Expression and Purification of Soluble, Recombinant Native-Like HIV-1 Envelope Glycoprotein Trimers by Targeted Sequence Changes.
    Ringe RP; Ozorowski G; Yasmeen A; Cupo A; Cruz Portillo VM; Pugach P; Golabek M; Rantalainen K; Holden LG; Cottrell CA; Wilson IA; Sanders RW; Ward AB; Klasse PJ; Moore JP
    J Virol; 2017 Jun; 91(12):. PubMed ID: 28381572
    [TBL] [Abstract][Full Text] [Related]  

  • 7. A VRC13-like bNAb response is associated with complex escape pathways in HIV-1 envelope.
    Joshi VR; Claiborne DT; Pack ML; Power KA; Newman RM; Batorsky R; Bean DJ; Goroff MS; Lingwood D; Seaman MS; Rosenberg E; Allen TM
    J Virol; 2024 Mar; 98(3):e0172023. PubMed ID: 38412036
    [TBL] [Abstract][Full Text] [Related]  

  • 8. VSV-Displayed HIV-1 Envelope Identifies Broadly Neutralizing Antibodies Class-Switched to IgG and IgA.
    Jia M; Liberatore RA; Guo Y; Chan KW; Pan R; Lu H; Waltari E; Mittler E; Chandran K; Finzi A; Kaufmann DE; Seaman MS; Ho DD; Shapiro L; Sheng Z; Kong XP; Bieniasz PD; Wu X
    Cell Host Microbe; 2020 Jun; 27(6):963-975.e5. PubMed ID: 32315598
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Neutralizing Antibody Responses Induced by HIV-1 Envelope Glycoprotein SOSIP Trimers Derived from Elite Neutralizers.
    Schorcht A; van den Kerkhof TLGM; Cottrell CA; Allen JD; Torres JL; Behrens AJ; Schermer EE; Burger JA; de Taeye SW; Torrents de la Peña A; Bontjer I; Gumbs S; Ozorowski G; LaBranche CC; de Val N; Yasmeen A; Klasse PJ; Montefiori DC; Moore JP; Schuitemaker H; Crispin M; van Gils MJ; Ward AB; Sanders RW
    J Virol; 2020 Nov; 94(24):. PubMed ID: 32999024
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Structure-based design of native-like HIV-1 envelope trimers to silence non-neutralizing epitopes and eliminate CD4 binding.
    Kulp DW; Steichen JM; Pauthner M; Hu X; Schiffner T; Liguori A; Cottrell CA; Havenar-Daughton C; Ozorowski G; Georgeson E; Kalyuzhniy O; Willis JR; Kubitz M; Adachi Y; Reiss SM; Shin M; de Val N; Ward AB; Crotty S; Burton DR; Schief WR
    Nat Commun; 2017 Nov; 8(1):1655. PubMed ID: 29162799
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Rational Engraftment of Quaternary-Interactive Acidic Loops for Anti-HIV-1 Antibody Improvement.
    Liu Q; Zhang P; Miao H; Lin Y; Kwon YD; Kwong PD; Rikhtegaran-Tehrani Z; Seaman MS; DeVico AL; Sajadi MM; Lusso P
    J Virol; 2021 May; 95(12):. PubMed ID: 33827946
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Elicitation of Neutralizing Antibodies Targeting the V2 Apex of the HIV Envelope Trimer in a Wild-Type Animal Model.
    Voss JE; Andrabi R; McCoy LE; de Val N; Fuller RP; Messmer T; Su CY; Sok D; Khan SN; Garces F; Pritchard LK; Wyatt RT; Ward AB; Crispin M; Wilson IA; Burton DR
    Cell Rep; 2017 Oct; 21(1):222-235. PubMed ID: 28978475
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Recombinant HIV envelope proteins fail to engage germline versions of anti-CD4bs bNAbs.
    Hoot S; McGuire AT; Cohen KW; Strong RK; Hangartner L; Klein F; Diskin R; Scheid JF; Sather DN; Burton DR; Stamatatos L
    PLoS Pathog; 2013 Jan; 9(1):e1003106. PubMed ID: 23300456
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Structure-Based Design of a Soluble Prefusion-Closed HIV-1 Env Trimer with Reduced CD4 Affinity and Improved Immunogenicity.
    Chuang GY; Geng H; Pancera M; Xu K; Cheng C; Acharya P; Chambers M; Druz A; Tsybovsky Y; Wanninger TG; Yang Y; Doria-Rose NA; Georgiev IS; Gorman J; Joyce MG; O'Dell S; Zhou T; McDermott AB; Mascola JR; Kwong PD
    J Virol; 2017 May; 91(10):. PubMed ID: 28275193
    [TBL] [Abstract][Full Text] [Related]  

  • 15. A Rare Mutation in an Infant-Derived HIV-1 Envelope Glycoprotein Alters Interprotomer Stability and Susceptibility to Broadly Neutralizing Antibodies Targeting the Trimer Apex.
    Mishra N; Sharma S; Dobhal A; Kumar S; Chawla H; Singh R; Das BK; Kabra SK; Lodha R; Luthra K
    J Virol; 2020 Sep; 94(19):. PubMed ID: 32669335
    [TBL] [Abstract][Full Text] [Related]  

  • 16. A native-like SOSIP.664 trimer based on an HIV-1 subtype B env gene.
    Pugach P; Ozorowski G; Cupo A; Ringe R; Yasmeen A; de Val N; Derking R; Kim HJ; Korzun J; Golabek M; de Los Reyes K; Ketas TJ; Julien JP; Burton DR; Wilson IA; Sanders RW; Klasse PJ; Ward AB; Moore JP
    J Virol; 2015 Mar; 89(6):3380-95. PubMed ID: 25589637
    [TBL] [Abstract][Full Text] [Related]  

  • 17. A next-generation cleaved, soluble HIV-1 Env trimer, BG505 SOSIP.664 gp140, expresses multiple epitopes for broadly neutralizing but not non-neutralizing antibodies.
    Sanders RW; Derking R; Cupo A; Julien JP; Yasmeen A; de Val N; Kim HJ; Blattner C; de la Peña AT; Korzun J; Golabek M; de Los Reyes K; Ketas TJ; van Gils MJ; King CR; Wilson IA; Ward AB; Klasse PJ; Moore JP
    PLoS Pathog; 2013 Sep; 9(9):e1003618. PubMed ID: 24068931
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Co-evolution of HIV Envelope and Apex-Targeting Neutralizing Antibody Lineage Provides Benchmarks for Vaccine Design.
    Rantalainen K; Berndsen ZT; Murrell S; Cao L; Omorodion O; Torres JL; Wu M; Umotoy J; Copps J; Poignard P; Landais E; Paulson JC; Wilson IA; Ward AB
    Cell Rep; 2018 Jun; 23(11):3249-3261. PubMed ID: 29898396
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Changes in Structure and Antigenicity of HIV-1 Env Trimers Resulting from Removal of a Conserved CD4 Binding Site-Proximal Glycan.
    Liang Y; Guttman M; Williams JA; Verkerke H; Alvarado D; Hu SL; Lee KK
    J Virol; 2016 Oct; 90(20):9224-36. PubMed ID: 27489265
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Characterization of a stable HIV-1 B/C recombinant, soluble, and trimeric envelope glycoprotein (Env) highly resistant to CD4-induced conformational changes.
    Kumar R; Ozorowski G; Kumar V; Holden LG; Shrivastava T; Patil S; Deshpande S; Ward AB; Bhattacharya J
    J Biol Chem; 2017 Sep; 292(38):15849-15858. PubMed ID: 28743743
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 32.