166 related articles for article (PubMed ID: 31528692)
1. Designing and repurposing drugs to target intrinsically disordered proteins for cancer treatment: using NUPR1 as a paradigm.
Santofimia-Castaño P; Rizzuti B; Xia Y; Abian O; Peng L; Velázquez-Campoy A; Iovanna JL; Neira JL
Mol Cell Oncol; 2019; 6(5):e1612678. PubMed ID: 31528692
[TBL] [Abstract][Full Text] [Related]
2. Design of Inhibitors of the Intrinsically Disordered Protein NUPR1: Balance between Drug Affinity and Target Function.
Rizzuti B; Lan W; Santofimia-Castaño P; Zhou Z; Velázquez-Campoy A; Abián O; Peng L; Neira JL; Xia Y; Iovanna JL
Biomolecules; 2021 Oct; 11(10):. PubMed ID: 34680086
[TBL] [Abstract][Full Text] [Related]
3. Targeting intrinsically disordered proteins involved in cancer.
Santofimia-Castaño P; Rizzuti B; Xia Y; Abian O; Peng L; Velázquez-Campoy A; Neira JL; Iovanna J
Cell Mol Life Sci; 2020 May; 77(9):1695-1707. PubMed ID: 31667555
[TBL] [Abstract][Full Text] [Related]
4. Amphipathic helical peptides hamper protein-protein interactions of the intrinsically disordered chromatin nuclear protein 1 (NUPR1).
Santofimia-Castaño P; Rizzuti B; Abián O; Velázquez-Campoy A; Iovanna JL; Neira JL
Biochim Biophys Acta Gen Subj; 2018 Jun; 1862(6):1283-1295. PubMed ID: 29530795
[TBL] [Abstract][Full Text] [Related]
5. Identification of a Drug Targeting an Intrinsically Disordered Protein Involved in Pancreatic Adenocarcinoma.
Neira JL; Bintz J; Arruebo M; Rizzuti B; Bonacci T; Vega S; Lanas A; Velázquez-Campoy A; Iovanna JL; Abián O
Sci Rep; 2017 Jan; 7():39732. PubMed ID: 28054562
[TBL] [Abstract][Full Text] [Related]
6. Dynamics of the intrinsically disordered protein NUPR1 in isolation and in its fuzzy complexes with DNA and prothymosin α.
Neira JL; Palomino-Schätzlein M; Ricci C; Ortore MG; Rizzuti B; Iovanna JL
Biochim Biophys Acta Proteins Proteom; 2019 Nov; 1867(11):140252. PubMed ID: 31325636
[TBL] [Abstract][Full Text] [Related]
7. Targeting the Stress-Induced Protein NUPR1 to Treat Pancreatic Adenocarcinoma.
Santofimia-Castaño P; Xia Y; Peng L; Velázquez-Campoy A; Abián O; Lan W; Lomberk G; Urrutia R; Rizzuti B; Soubeyran P; Neira JL; Iovanna J
Cells; 2019 Nov; 8(11):. PubMed ID: 31744261
[TBL] [Abstract][Full Text] [Related]
8. Crowding Effects on the Structure and Dynamics of the Intrinsically Disordered Nuclear Chromatin Protein NUPR1.
Bonucci A; Palomino-Schätzlein M; Malo de Molina P; Arbe A; Pierattelli R; Rizzuti B; Iovanna JL; Neira JL
Front Mol Biosci; 2021; 8():684622. PubMed ID: 34291085
[TBL] [Abstract][Full Text] [Related]
9. The chromatin nuclear protein NUPR1L is intrinsically disordered and binds to the same proteins as its paralogue.
Neira JL; López MB; Sevilla P; Rizzuti B; Cámara-Artigas A; Vidal M; Iovanna JL
Biochem J; 2018 Jul; 475(14):2271-2291. PubMed ID: 29925531
[TBL] [Abstract][Full Text] [Related]
10. Intrinsically disordered chromatin protein NUPR1 binds to the C-terminal region of Polycomb RING1B.
Santofimia-Castaño P; Rizzuti B; Pey ÁL; Soubeyran P; Vidal M; Urrutia R; Iovanna JL; Neira JL
Proc Natl Acad Sci U S A; 2017 Aug; 114(31):E6332-E6341. PubMed ID: 28720707
[TBL] [Abstract][Full Text] [Related]
11. Determinants of the pKa values of ionizable residues in an intrinsically disordered protein.
Neira JL; Rizzuti B; Iovanna JL
Arch Biochem Biophys; 2016 May; 598():18-27. PubMed ID: 27046343
[TBL] [Abstract][Full Text] [Related]
12. Intrinsically Disordered Chromatin Protein NUPR1 Binds to the Enzyme PADI4.
Araujo-Abad S; Neira JL; Rizzuti B; García-Morales P; de Juan Romero C; Santofimia-Castaño P; Iovanna J
J Mol Biol; 2023 Apr; 435(8):168033. PubMed ID: 36858171
[TBL] [Abstract][Full Text] [Related]
13. Development of Charge-Augmented Three-Point Water Model (CAIPi3P) for Accurate Simulations of Intrinsically Disordered Proteins.
de Souza JV; Zariquiey FS; Bronowska AK
Int J Mol Sci; 2020 Aug; 21(17):. PubMed ID: 32859072
[TBL] [Abstract][Full Text] [Related]
14. A Phosphorylation-Induced Switch in the Nuclear Localization Sequence of the Intrinsically Disordered NUPR1 Hampers Binding to Importin.
Neira JL; Rizzuti B; Jiménez-Alesanco A; Palomino-Schätzlein M; Abián O; Velázquez-Campoy A; Iovanna JL
Biomolecules; 2020 Sep; 10(9):. PubMed ID: 32933064
[TBL] [Abstract][Full Text] [Related]
15. Druggability of Intrinsically Disordered Proteins.
Joshi P; Vendruscolo M
Adv Exp Med Biol; 2015; 870():383-400. PubMed ID: 26387110
[TBL] [Abstract][Full Text] [Related]
16. Features of molecular recognition of intrinsically disordered proteins via coupled folding and binding.
Yang J; Gao M; Xiong J; Su Z; Huang Y
Protein Sci; 2019 Nov; 28(11):1952-1965. PubMed ID: 31441158
[TBL] [Abstract][Full Text] [Related]
17. Novel strategies for drug discovery based on Intrinsically Disordered Proteins (IDPs).
Wang J; Cao Z; Zhao L; Li S
Int J Mol Sci; 2011; 12(5):3205-19. PubMed ID: 21686180
[TBL] [Abstract][Full Text] [Related]
18. Genetic inactivation of Nupr1 acts as a dominant suppressor event in a two-hit model of pancreatic carcinogenesis.
Cano CE; Hamidi T; Garcia MN; Grasso D; Loncle C; Garcia S; Calvo E; Lomberk G; Dusetti N; Bartholin L; Urrutia R; Iovanna JL
Gut; 2014 Jun; 63(6):984-95. PubMed ID: 24026351
[TBL] [Abstract][Full Text] [Related]
19. Dendrimers as Competitors of Protein-Protein Interactions of the Intrinsically Disordered Nuclear Chromatin Protein NUPR1.
Neira JL; Correa J; Rizzuti B; Santofimia-Castaño P; Abian O; Velázquez-Campoy A; Fernandez-Megia E; Iovanna JL
Biomacromolecules; 2019 Jul; 20(7):2567-2576. PubMed ID: 31181156
[TBL] [Abstract][Full Text] [Related]
20. On the Potential of Machine Learning to Examine the Relationship Between Sequence, Structure, Dynamics and Function of Intrinsically Disordered Proteins.
Lindorff-Larsen K; Kragelund BB
J Mol Biol; 2021 Oct; 433(20):167196. PubMed ID: 34390736
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]