BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

403 related articles for article (PubMed ID: 31533039)

  • 1. Dual Processing of R-Loops and Topoisomerase I Induces Transcription-Dependent DNA Double-Strand Breaks.
    Cristini A; Ricci G; Britton S; Salimbeni S; Huang SN; Marinello J; Calsou P; Pommier Y; Favre G; Capranico G; Gromak N; Sordet O
    Cell Rep; 2019 Sep; 28(12):3167-3181.e6. PubMed ID: 31533039
    [TBL] [Abstract][Full Text] [Related]  

  • 2. TDP1 mutation causing SCAN1 neurodegenerative syndrome hampers the repair of transcriptional DNA double-strand breaks.
    Geraud M; Cristini A; Salimbeni S; Bery N; Jouffret V; Russo M; Ajello AC; Fernandez Martinez L; Marinello J; Cordelier P; Trouche D; Favre G; Nicolas E; Capranico G; Sordet O
    Cell Rep; 2024 May; 43(5):114214. PubMed ID: 38761375
    [TBL] [Abstract][Full Text] [Related]  

  • 3. DNA-PK triggers histone ubiquitination and signaling in response to DNA double-strand breaks produced during the repair of transcription-blocking topoisomerase I lesions.
    Cristini A; Park JH; Capranico G; Legube G; Favre G; Sordet O
    Nucleic Acids Res; 2016 Feb; 44(3):1161-78. PubMed ID: 26578593
    [TBL] [Abstract][Full Text] [Related]  

  • 4. FEN1 participates in repair of the 5'-phosphotyrosyl terminus of DNA single-strand breaks.
    Kametani Y; Takahata C; Narita T; Tanaka K; Iwai S; Kuraoka I
    Carcinogenesis; 2016 Jan; 37(1):56-62. PubMed ID: 26581212
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Transcription-dependent DNA double-strand breaks and human disease.
    Cristini A; Gromak N; Sordet O
    Mol Cell Oncol; 2020; 7(2):1691905. PubMed ID: 32158914
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Transcription-coupled nucleotide excision repair factors promote R-loop-induced genome instability.
    Sollier J; Stork CT; García-Rubio ML; Paulsen RD; Aguilera A; Cimprich KA
    Mol Cell; 2014 Dec; 56(6):777-85. PubMed ID: 25435140
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Human Rad52 Promotes XPG-Mediated R-loop Processing to Initiate Transcription-Associated Homologous Recombination Repair.
    Yasuhara T; Kato R; Hagiwara Y; Shiotani B; Yamauchi M; Nakada S; Shibata A; Miyagawa K
    Cell; 2018 Oct; 175(2):558-570.e11. PubMed ID: 30245011
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Ataxia telangiectasia mutated activation by transcription- and topoisomerase I-induced DNA double-strand breaks.
    Sordet O; Redon CE; Guirouilh-Barbat J; Smith S; Solier S; Douarre C; Conti C; Nakamura AJ; Das BB; Nicolas E; Kohn KW; Bonner WM; Pommier Y
    EMBO Rep; 2009 Aug; 10(8):887-93. PubMed ID: 19557000
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Human DNA topoisomerase I poisoning causes R loop-mediated genome instability attenuated by transcription factor IIS.
    Duardo RC; Marinello J; Russo M; Morelli S; Pepe S; Guerra F; Gómez-González B; Aguilera A; Capranico G
    Sci Adv; 2024 May; 10(21):eadm8196. PubMed ID: 38787953
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Tdp1 processes chromate-induced single-strand DNA breaks that collapse replication forks.
    Ganguly A; Guo L; Sun L; Suo F; Du LL; Russell P
    PLoS Genet; 2018 Aug; 14(8):e1007595. PubMed ID: 30148840
    [TBL] [Abstract][Full Text] [Related]  

  • 11. DNA double-strand breaks and ATM activation by transcription-blocking DNA lesions.
    Sordet O; Nakamura AJ; Redon CE; Pommier Y
    Cell Cycle; 2010 Jan; 9(2):274-8. PubMed ID: 20023421
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The distinctive cellular responses to DNA strand breaks caused by a DNA topoisomerase I poison in conjunction with DNA replication and RNA transcription.
    Sakasai R; Iwabuchi K
    Genes Genet Syst; 2016; 90(4):187-94. PubMed ID: 26616758
    [TBL] [Abstract][Full Text] [Related]  

  • 13. H. pylori-Induced DNA Strand Breaks Are Introduced by Nucleotide Excision Repair Endonucleases and Promote NF-κB Target Gene Expression.
    Hartung ML; Gruber DC; Koch KN; Grüter L; Rehrauer H; Tegtmeyer N; Backert S; Müller A
    Cell Rep; 2015 Oct; 13(1):70-79. PubMed ID: 26411687
    [TBL] [Abstract][Full Text] [Related]  

  • 14. A human 5'-tyrosyl DNA phosphodiesterase that repairs topoisomerase-mediated DNA damage.
    Cortes Ledesma F; El Khamisy SF; Zuma MC; Osborn K; Caldecott KW
    Nature; 2009 Oct; 461(7264):674-8. PubMed ID: 19794497
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Synergistic decrease of DNA single-strand break repair rates in mouse neural cells lacking both Tdp1 and aprataxin.
    El-Khamisy SF; Katyal S; Patel P; Ju L; McKinnon PJ; Caldecott KW
    DNA Repair (Amst); 2009 Jun; 8(6):760-6. PubMed ID: 19303373
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Flap Endonuclease 1 Endonucleolytically Processes RNA to Resolve R-Loops through DNA Base Excision Repair.
    Laverde EE; Polyzos AA; Tsegay PP; Shaver M; Hutcheson JD; Balakrishnan L; McMurray CT; Liu Y
    Genes (Basel); 2022 Dec; 14(1):. PubMed ID: 36672839
    [TBL] [Abstract][Full Text] [Related]  

  • 17. RAP80 suppresses the vulnerability of R-loops during DNA double-strand break repair.
    Yasuhara T; Kato R; Yamauchi M; Uchihara Y; Zou L; Miyagawa K; Shibata A
    Cell Rep; 2022 Feb; 38(5):110335. PubMed ID: 35108530
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.
    Kim JJ; Lee SY; Gong F; Battenhouse AM; Boutz DR; Bashyal A; Refvik ST; Chiang CM; Xhemalce B; Paull TT; Brodbelt JS; Marcotte EM; Miller KM
    Genes Dev; 2019 Dec; 33(23-24):1751-1774. PubMed ID: 31753913
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Topoisomerase 1 prevents replication stress at R-loop-enriched transcription termination sites.
    Promonet A; Padioleau I; Liu Y; Sanz L; Biernacka A; Schmitz AL; Skrzypczak M; Sarrazin A; Mettling C; Rowicka M; Ginalski K; Chedin F; Chen CL; Lin YL; Pasero P
    Nat Commun; 2020 Aug; 11(1):3940. PubMed ID: 32769985
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Transcriptional Stress Induces Chromatin Relocation of the Nucleotide Excision Repair Factor XPG.
    Scalera C; Ticli G; Dutto I; Cazzalini O; Stivala LA; Prosperi E
    Int J Mol Sci; 2021 Jun; 22(12):. PubMed ID: 34205418
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 21.