BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

122 related articles for article (PubMed ID: 31541801)

  • 1. Rational design of some substituted phenyl azanediyl (bis) methylene phosphonic acid derivatives as potential anticancer agents and imaging probes: Computational inputs, chemical synthesis, radiolabeling, biodistribution and gamma scintigraphy.
    Khedr MA; Rashed HM; Farag H; Sakr TM
    Bioorg Chem; 2019 Nov; 92():103282. PubMed ID: 31541801
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Oxiranylmethyloxy or thiiranylmethyloxy-azaxanthones and -acridone analogues as potential topoisomerase I inhibitors.
    Cho HJ; Jung MJ; Kwon Y; Na Y
    Bioorg Med Chem Lett; 2009 Dec; 19(23):6766-9. PubMed ID: 19836231
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Antifolate and antiproliferative activity of 6,8,10-triazaspiro[4.5]deca-6,8-dienes and 1,3,5-triazaspiro[5.5]undeca-1,3-dienes.
    Ma X; Chui WK
    Bioorg Med Chem; 2010 Jan; 18(2):737-43. PubMed ID: 20036565
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Design, synthesis, and biological evaluation of novel substituted thiourea derivatives as potential anticancer agents for NSCLC by blocking K-Ras protein-effectors interactions.
    Zhang Y; Meng X; Tang H; Cheng M; Yang F; Xu W
    J Enzyme Inhib Med Chem; 2020 Dec; 35(1):344-353. PubMed ID: 31851852
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Design, Synthesis, In Vitro Anti-cancer Activity, ADMET Profile and Molecular Docking of Novel Triazolo[3,4-a]phthalazine Derivatives Targeting VEGFR-2 Enzyme.
    El-Helby AA; Sakr H; Ayyad RRA; El-Adl K; Ali MM; Khedr F
    Anticancer Agents Med Chem; 2018; 18(8):1184-1196. PubMed ID: 29651967
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Structure-based virtual screening and biological evaluation of novel non-bisphosphonate farnesyl pyrophosphate synthase inhibitors.
    Liu Q; Miao Y; Wang X; Lv G; Peng Y; Li K; Li M; Qiu L; Lin J
    Eur J Med Chem; 2020 Jan; 186():111905. PubMed ID: 31785819
    [TBL] [Abstract][Full Text] [Related]  

  • 7. NMR for screening and a biochemical assay: Identification of new FPPS inhibitors exerting anticancer activity.
    Grimaldi M; Randino R; Ciaglia E; Scrima M; Buonocore M; Stillitano I; Abate M; Covelli V; Tosco A; Gazzerro P; Bifulco M; Rodriquez M; D'Ursi AM
    Bioorg Chem; 2020 May; 98():103449. PubMed ID: 32057422
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Synthesis, Characterization and Evaluation of Cytotoxic Activities of Novel Aziridinyl Phosphonic Acid Derivatives.
    Khan R; Ulusan S; Banerjee S; Dogan Ö
    Chem Biodivers; 2019 Nov; 16(11):e1900375. PubMed ID: 31512351
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Design, Synthesis, and Preliminary Bioactivity Evaluation of 2,7-Substituted Carbazole Derivatives as Potent Autotaxin Inhibitors and Antitumor Agents†.
    Wang W; Zhao F; Zhao Y; Pan W; Cao P; Wu L; Wang Z; Zhao X; Zhao Y; Wang H
    Anticancer Agents Med Chem; 2019; 19(2):256-264. PubMed ID: 30173652
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Dual functionality of phosphonic-acid-appended phthalocyanines: inhibitors of urokinase plasminogen activator and anticancer photodynamic agents.
    Venkatramaiah N; Pereira PM; Almeida Paz FA; Ribeiro CA; Fernandes R; Tomé JP
    Chem Commun (Camb); 2015 Nov; 51(85):15550-3. PubMed ID: 26352730
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Novel 5-azaindolocarbazoles as cytotoxic agents and Chk1 inhibitors.
    Lefoix M; Coudert G; Routier S; Pfeiffer B; Caignard DH; Hickman J; Pierré A; Golsteyn RM; Léonce S; Bossard C; Mérour JY
    Bioorg Med Chem; 2008 May; 16(9):5303-21. PubMed ID: 18342518
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Novel 3-(2-(3-methyl-5-substituted-phenyl-4,5-dihydropyrazol-1-yl)-2-oxoethoxy)-2-substituted-phenyl-4H-chromen-4-one: synthesis and anticancer activity.
    Liu XH; Li J; Wu FR; Song BA; Bhadury PS; Shi L
    Med Chem; 2011 Nov; 7(6):605-10. PubMed ID: 22313300
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Regioselective synthesis and in vitro anticancer activity of 4-aza-podophyllotoxin derivatives catalyzed by L-proline.
    Shi C; Wang J; Chen H; Shi D
    J Comb Chem; 2010 Jul; 12(4):430-4. PubMed ID: 20503973
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Azacoccone E inhibits cancer cell growth by targeting 3-phosphoglycerate dehydrogenase.
    Guo J; Gu X; Zheng M; Zhang Y; Chen L; Li H
    Bioorg Chem; 2019 Jun; 87():16-22. PubMed ID: 30852233
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Synthesis and evaluation of anticancer and antiobesity activity of 1-ethoxy carbonyl-3,5-bis (3'-indolyl methylene)-4-pyperidone analogs.
    Buduma K; Chinde S; Dommati AK; Sharma P; Shukla A; Srinivas KVNS; Arigari NK; Khan F; Tiwari AK; Grover P; Jonnala KK
    Bioorg Med Chem Lett; 2016 Mar; 26(6):1633-1638. PubMed ID: 26873414
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Diethylalkylsulfonamido(4-methoxyphenyl)methyl)phosphonate/phosphonic acid derivatives act as acid phosphatase inhibitors: synthesis accompanied by experimental and molecular modeling assessments.
    Alimoradi N; Ashrafi-Kooshk MR; Shahlaei M; Maghsoudi S; Adibi H; McGeary RP; Khodarahmi R
    J Enzyme Inhib Med Chem; 2017 Dec; 32(1):20-28. PubMed ID: 27766897
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Structure-Based Design: Synthesis, X-ray Crystallography, and Biological Evaluation of N-Substituted-4-Hydroxy-2-Quinolone-3-Carboxamides as Potential Cytotoxic Agents.
    Sabbah DA; Hishmah B; Sweidan K; Bardaweel S; AlDamen M; Zhong HA; Abu Khalaf R; Hasan Ibrahim A; Al-Qirim T; Abu Sheikha G; Mubarak MS
    Anticancer Agents Med Chem; 2018; 18(2):263-276. PubMed ID: 28901259
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Ethenesulfonyl fluoride derivatives as telomerase inhibitors: structure-based design, SAR, and anticancer evaluation in vitro.
    Chen X; Zha GF; Wang JQ; Liu XH
    J Enzyme Inhib Med Chem; 2018 Dec; 33(1):1266-1270. PubMed ID: 30139286
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Mechanism-based design, synthesis and biological studies of N⁵-substituted tetrahydrofolate analogs as inhibitors of cobalamin-dependent methionine synthase and potential anticancer agents.
    Zhang Z; Tian C; Zhou S; Wang W; Guo Y; Xia J; Liu Z; Wang B; Wang X; Golding BT; Griff RJ; Du Y; Liu J
    Eur J Med Chem; 2012 Dec; 58():228-36. PubMed ID: 23124219
    [TBL] [Abstract][Full Text] [Related]  

  • 20. One-Pot Three-Component Synthesis of Novel Diethyl((2-oxo-1,2-dihydroquinolin-3-yl)(arylamino)methyl)phosphonate as Potential Anticancer Agents.
    Fang YL; Wu ZL; Xiao MW; Tang YT; Li KM; Ye J; Xiang JN; Hu AX
    Int J Mol Sci; 2016 Apr; 17(5):. PubMed ID: 27136538
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.