These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

179 related articles for article (PubMed ID: 31541869)

  • 1. Identification of highly potent and selective Cdc25 protein phosphatases inhibitors from miniaturization click-chemistry-based combinatorial libraries.
    Jing L; Wu G; Hao X; Olotu FA; Kang D; Chen CH; Lee KH; Soliman MES; Liu X; Song Y; Zhan P
    Eur J Med Chem; 2019 Dec; 183():111696. PubMed ID: 31541869
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Discovery of potent and selective Cdc25 phosphatase inhibitors via rapid assembly and in situ screening of Quinonoid-focused libraries.
    Tao Y; Hao X; Jing L; Sun L; Cherukupalli S; Liu S; Wu G; Xu S; Zhang X; Shi X; Song Y; Liu X; Zhan P
    Bioorg Chem; 2021 Oct; 115():105254. PubMed ID: 34426152
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Discovery and biological evaluation of a new family of potent inhibitors of the dual specificity protein phosphatase Cdc25.
    Lazo JS; Aslan DC; Southwick EC; Cooley KA; Ducruet AP; Joo B; Vogt A; Wipf P
    J Med Chem; 2001 Nov; 44(24):4042-9. PubMed ID: 11708908
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Ligand-based chemoinformatic discovery of a novel small molecule inhibitor targeting CDC25 dual specificity phosphatases and displaying in vitro efficacy against melanoma cells.
    Capasso A; Cerchia C; Di Giovanni C; Granato G; Albano F; Romano S; De Vendittis E; Ruocco MR; Lavecchia A
    Oncotarget; 2015 Nov; 6(37):40202-22. PubMed ID: 26474275
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Effective Pharmacophore for CDC25 Phosphatases Enzyme Inhibitors: Newly Synthesized Bromothiazolopyrimidine Derivatives.
    El-Shahat M; Salama MAM; El-Farargy AF; Ali MM; Ahmed DM
    Mini Rev Med Chem; 2021; 21(1):118-131. PubMed ID: 32560601
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Structure-based development of novel triazoles and related thiazolotriazoles as anticancer agents and Cdc25A/B phosphatase inhibitors. Synthesis, in vitro biological evaluation, molecular docking and in silico ADME-T studies.
    Rostom SAF; Badr MH; Abd El Razik HA; Ashour HMA
    Eur J Med Chem; 2017 Oct; 139():263-279. PubMed ID: 28803043
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Synthesis, anticancer activity, and molecular modeling of 1,4-naphthoquinones that inhibit MKK7 and Cdc25.
    Schepetkin IA; Karpenko AS; Khlebnikov AI; Shibinska MO; Levandovskiy IA; Kirpotina LN; Danilenko NV; Quinn MT
    Eur J Med Chem; 2019 Dec; 183():111719. PubMed ID: 31563013
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Synthesis and biological evaluation of novel coumarin-based inhibitors of Cdc25 phosphatases.
    Valente S; Bana E; Viry E; Bagrel D; Kirsch G
    Bioorg Med Chem Lett; 2010 Oct; 20(19):5827-30. PubMed ID: 20800482
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Discovery and characterization of novel imidazopyridine derivative CHEQ-2 as a potent CDC25 inhibitor and promising anticancer drug candidate.
    Song Y; Lin X; Kang D; Li X; Zhan P; Liu X; Zhang Q
    Eur J Med Chem; 2014 Jul; 82():293-307. PubMed ID: 24922544
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Discovery of new inhibitors of Cdc25B dual specificity phosphatases by structure-based virtual screening.
    Lavecchia A; Di Giovanni C; Pesapane A; Montuori N; Ragno P; Martucci NM; Masullo M; De Vendittis E; Novellino E
    J Med Chem; 2012 May; 55(9):4142-58. PubMed ID: 22524450
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Rapid discovery of triazolobenzylidene-thiazolopyrimidines (TBTP) as CDC25 phosphatase inhibitors by parallel click chemistry and in situ screening.
    Duval R; Kolb S; Braud E; Genest D; Garbay C
    J Comb Chem; 2009; 11(6):947-50. PubMed ID: 19835352
    [No Abstract]   [Full Text] [Related]  

  • 12. Design and synthesis of novel bis-thiazolone derivatives as micromolar CDC25 phosphatase inhibitors: effect of dimerisation on phosphatase inhibition.
    Sarkis M; Tran DN; Kolb S; Miteva MA; Villoutreix BO; Garbay C; Braud E
    Bioorg Med Chem Lett; 2012 Dec; 22(24):7345-50. PubMed ID: 23141909
    [TBL] [Abstract][Full Text] [Related]  

  • 13. 3D QSAR Pharmacophore Based Virtual Screening for Identification of Potential Inhibitors for CDC25B.
    Ma Y; Li HL; Chen XB; Jin WY; Zhou H; Ma Y; Wang RL
    Comput Biol Chem; 2018 Apr; 73():1-12. PubMed ID: 29413811
    [TBL] [Abstract][Full Text] [Related]  

  • 14. A novel synthetic inhibitor of CDC25 phosphatases: BN82002.
    Brezak MC; Quaranta M; Mondésert O; Galcera MO; Lavergne O; Alby F; Cazales M; Baldin V; Thurieau C; Harnett J; Lanco C; Kasprzyk PG; Prevost GP; Ducommun B
    Cancer Res; 2004 May; 64(9):3320-5. PubMed ID: 15126376
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Cdc25B dual-specificity phosphatase inhibitors identified in a high-throughput screen of the NIH compound library.
    Johnston PA; Foster CA; Tierno MB; Shun TY; Shinde SN; Paquette WD; Brummond KM; Wipf P; Lazo JS
    Assay Drug Dev Technol; 2009 Jun; 7(3):250-65. PubMed ID: 19530895
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Medicinal chemistry insights into novel CDC25 inhibitors.
    Tao Y; Hao X; Ding X; Cherukupalli S; Song Y; Liu X; Zhan P
    Eur J Med Chem; 2020 Sep; 201():112374. PubMed ID: 32603979
    [TBL] [Abstract][Full Text] [Related]  

  • 17. CDC25A and B dual-specificity phosphatase inhibitors: potential agents for cancer therapy.
    Lavecchia A; Di Giovanni C; Novellino E
    Curr Med Chem; 2009; 16(15):1831-49. PubMed ID: 19442149
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Synthesis, biological evaluation and molecular modeling studies on novel quinonoid inhibitors of CDC25 phosphatases.
    Evain-Bana E; Schiavo L; Bour C; Lanfranchi DA; Berardozzi S; Ghirga F; Bagrel D; Botta B; Hanquet G; Mori M
    J Enzyme Inhib Med Chem; 2017 Dec; 32(1):113-118. PubMed ID: 27774816
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Identification of a potent and selective pharmacophore for Cdc25 dual specificity phosphatase inhibitors.
    Lazo JS; Nemoto K; Pestell KE; Cooley K; Southwick EC; Mitchell DA; Furey W; Gussio R; Zaharevitz DW; Joo B; Wipf P
    Mol Pharmacol; 2002 Apr; 61(4):720-8. PubMed ID: 11901209
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Cdc25B phosphatase inhibitors in cancer therapy: latest developments, trends and medicinal chemistry perspective.
    Lavecchia A; Coluccia A; Di Giovanni C; Novellino E
    Anticancer Agents Med Chem; 2008 Dec; 8(8):843-56. PubMed ID: 19075567
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.