These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

211 related articles for article (PubMed ID: 31543469)

  • 1. Pathological Progression Induced by the Frontotemporal Dementia-Associated R406W Tau Mutation in Patient-Derived iPSCs.
    Nakamura M; Shiozawa S; Tsuboi D; Amano M; Watanabe H; Maeda S; Kimura T; Yoshimatsu S; Kisa F; Karch CM; Miyasaka T; Takashima A; Sahara N; Hisanaga SI; Ikeuchi T; Kaibuchi K; Okano H
    Stem Cell Reports; 2019 Oct; 13(4):684-699. PubMed ID: 31543469
    [TBL] [Abstract][Full Text] [Related]  

  • 2. MMP-9 and MMP-2 Contribute to Neuronal Cell Death in iPSC Models of Frontotemporal Dementia with MAPT Mutations.
    Biswas MHU; Almeida S; Lopez-Gonzalez R; Mao W; Zhang Z; Karydas A; Geschwind MD; Biernat J; Mandelkow EM; Futai K; Miller BL; Gao FB
    Stem Cell Reports; 2016 Sep; 7(3):316-324. PubMed ID: 27594586
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Defective proteostasis in induced pluripotent stem cell models of frontotemporal lobar degeneration.
    Mahali S; Martinez R; King M; Verbeck A; Harari O; Benitez BA; Horie K; Sato C; Temple S; Karch CM
    Transl Psychiatry; 2022 Dec; 12(1):508. PubMed ID: 36494352
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Developmental regulation of tau splicing is disrupted in stem cell-derived neurons from frontotemporal dementia patients with the 10 + 16 splice-site mutation in MAPT.
    Sposito T; Preza E; Mahoney CJ; Setó-Salvia N; Ryan NS; Morris HR; Arber C; Devine MJ; Houlden H; Warner TT; Bushell TJ; Zagnoni M; Kunath T; Livesey FJ; Fox NC; Rossor MN; Hardy J; Wray S
    Hum Mol Genet; 2015 Sep; 24(18):5260-9. PubMed ID: 26136155
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Integrative system biology analyses of CRISPR-edited iPSC-derived neurons and human brains reveal deficiencies of presynaptic signaling in FTLD and PSP.
    Jiang S; Wen N; Li Z; Dube U; Del Aguila J; Budde J; Martinez R; Hsu S; Fernandez MV; Cairns NJ; ; ; Harari O; Cruchaga C; Karch CM
    Transl Psychiatry; 2018 Dec; 8(1):265. PubMed ID: 30546007
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Induced pluripotent stem cells (iPSCs) derived from a pre-symptomatic carrier of a R406W mutation in microtubule-associated protein tau (MAPT) causing frontotemporal dementia.
    Rasmussen MA; Hjermind LE; Hasholt LF; Waldemar G; Nielsen JE; Clausen C; Hyttel P; Holst B
    Stem Cell Res; 2016 Jan; 16(1):105-9. PubMed ID: 27345791
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Frontotemporal dementia-associated N279K tau mutant disrupts subcellular vesicle trafficking and induces cellular stress in iPSC-derived neural stem cells.
    Wren MC; Zhao J; Liu CC; Murray ME; Atagi Y; Davis MD; Fu Y; Okano HJ; Ogaki K; Strongosky AJ; Tacik P; Rademakers R; Ross OA; Dickson DW; Wszolek ZK; Kanekiyo T; Bu G
    Mol Neurodegener; 2015 Sep; 10():46. PubMed ID: 26373282
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Modelling frontotemporal dementia using patient-derived induced pluripotent stem cells.
    Lines G; Casey JM; Preza E; Wray S
    Mol Cell Neurosci; 2020 Dec; 109():103553. PubMed ID: 32956830
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Human iPSC-Derived Neuronal Model of Tau-A152T Frontotemporal Dementia Reveals Tau-Mediated Mechanisms of Neuronal Vulnerability.
    Silva MC; Cheng C; Mair W; Almeida S; Fong H; Biswas MHU; Zhang Z; Huang Y; Temple S; Coppola G; Geschwind DH; Karydas A; Miller BL; Kosik KS; Gao FB; Steen JA; Haggarty SJ
    Stem Cell Reports; 2016 Sep; 7(3):325-340. PubMed ID: 27594585
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Distinct Neurodegenerative Changes in an Induced Pluripotent Stem Cell Model of Frontotemporal Dementia Linked to Mutant TAU Protein.
    Ehrlich M; Hallmann AL; Reinhardt P; Araúzo-Bravo MJ; Korr S; Röpke A; Psathaki OE; Ehling P; Meuth SG; Oblak AL; Murrell JR; Ghetti B; Zaehres H; Schöler HR; Sterneckert J; Kuhlmann T; Hargus G
    Stem Cell Reports; 2015 Jul; 5(1):83-96. PubMed ID: 26143746
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Inhibition of p25/Cdk5 Attenuates Tauopathy in Mouse and iPSC Models of Frontotemporal Dementia.
    Seo J; Kritskiy O; Watson LA; Barker SJ; Dey D; Raja WK; Lin YT; Ko T; Cho S; Penney J; Silva MC; Sheridan SD; Lucente D; Gusella JF; Dickerson BC; Haggarty SJ; Tsai LH
    J Neurosci; 2017 Oct; 37(41):9917-9924. PubMed ID: 28912154
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Induced pluripotent stem cells (iPSCs) derived from a patient with frontotemporal dementia caused by a R406W mutation in microtubule-associated protein tau (MAPT).
    Rasmussen MA; Hjermind LE; Hasholt LF; Waldemar G; Nielsen JE; Clausen C; Hyttel P; Holst B
    Stem Cell Res; 2016 Jan; 16(1):75-8. PubMed ID: 27345789
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Generation of an isogenic, gene-corrected iPSC line from a symptomatic 59-year-old female patient with frontotemporal dementia caused by an R406W mutation in the microtubule associated protein tau (MAPT) gene.
    Nimsanor N; Poulsen U; Rasmussen MA; Clausen C; Mau-Holzmann UA; Nielsen JE; Nielsen TT; Hyttel P; Holst B; Schmid B
    Stem Cell Res; 2016 Nov; 17(3):576-579. PubMed ID: 27934586
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Astrocyte pathology in a human neural stem cell model of frontotemporal dementia caused by mutant TAU protein.
    Hallmann AL; Araúzo-Bravo MJ; Mavrommatis L; Ehrlich M; Röpke A; Brockhaus J; Missler M; Sterneckert J; Schöler HR; Kuhlmann T; Zaehres H; Hargus G
    Sci Rep; 2017 Mar; 7():42991. PubMed ID: 28256506
    [TBL] [Abstract][Full Text] [Related]  

  • 15. iPSC-induced neurons with the V337M MAPT mutation are selectively vulnerable to caspase-mediated cleavage of tau and apoptotic cell death.
    Theofilas P; Wang C; Butler D; Morales DO; Petersen C; Ambrose A; Chin B; Yang T; Khan S; Ng R; Kayed R; Karch CM; Miller BL; Gestwicki JE; Gan L; Temple S; Arkin MR; Grinberg LT
    Mol Cell Neurosci; 2024 Sep; 130():103954. PubMed ID: 39032719
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Induced pluripotent stem cells (iPSCs) derived from a patient with frontotemporal dementia caused by a P301L mutation in microtubule-associated protein tau (MAPT).
    Rasmussen MA; Hjermind LE; Hasholt LF; Waldemar G; Nielsen JE; Clausen C; Hyttel P; Holst B
    Stem Cell Res; 2016 Jan; 16(1):70-4. PubMed ID: 27345788
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Patients carrying the mutation p.R406W in MAPT present with non-conforming phenotypic spectrum.
    Gossye H; Van Mossevelde S; Sieben A; Bjerke M; Hendrickx Van de Craen E; van der Zee J; De Deyn PP; De Bleecker J; Versijpt J; van den Ende J; Deryck O; Bourgeois P; Bier JC; Goethals M; Vandenberghe R; Engelborghs S; Van Broeckhoven C
    Brain; 2023 Apr; 146(4):1624-1636. PubMed ID: 36171642
    [TBL] [Abstract][Full Text] [Related]  

  • 18. 18F-MK-6240 tau-PET in genetic frontotemporal dementia.
    Levy JP; Bezgin G; Savard M; Pascoal TA; Finger E; Laforce R; Sonnen JA; Soucy JP; Gauthier S; Rosa-Neto P; Ducharme S
    Brain; 2022 Jun; 145(5):1763-1772. PubMed ID: 34664612
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Tau inhibits mitochondrial calcium efflux and makes neurons vulnerable to calcium-induced cell death.
    Britti E; Ros J; Esteras N; Abramov AY
    Cell Calcium; 2020 Mar; 86():102150. PubMed ID: 31918031
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Modeling of Frontotemporal Dementia Using iPSC Technology.
    Kim M; Kim HJ; Koh W; Li L; Heo H; Cho H; Lyoo CH; Seo SW; Kim EJ; Nakanishi M; Na DL; Song J
    Int J Mol Sci; 2020 Jul; 21(15):. PubMed ID: 32727073
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.