These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
2. A split-GFP tool reveals differences in the sub-mitochondrial distribution of wt and mutant alpha-synuclein. Vicario M; Cieri D; Vallese F; Catoni C; Barazzuol L; Berto P; Grinzato A; Barbieri L; Brini M; Calì T Cell Death Dis; 2019 Nov; 10(11):857. PubMed ID: 31719530 [TBL] [Abstract][Full Text] [Related]
3. Intracerebral Administration of a Ligand-ASO Conjugate Selectively Reduces α-Synuclein Accumulation in Monoamine Neurons of Double Mutant Human A30P*A53T*α-Synuclein Transgenic Mice. Pavia-Collado R; Cóppola-Segovia V; Miquel-Rio L; Alarcón-Aris D; Rodríguez-Aller R; Torres-López M; Paz V; Ruiz-Bronchal E; Campa L; Artigas F; Montefeltro A; Revilla R; Bortolozzi A Int J Mol Sci; 2021 Mar; 22(6):. PubMed ID: 33805843 [TBL] [Abstract][Full Text] [Related]
4. Involvement of mortalin/GRP75/mthsp70 in the mitochondrial impairments induced by A53T mutant α-synuclein. Liu FT; Chen Y; Yang YJ; Yang L; Yu M; Zhao J; Wu JJ; Huang F; Liu W; Ding ZT; Wang J Brain Res; 2015 Apr; 1604():52-61. PubMed ID: 25665531 [TBL] [Abstract][Full Text] [Related]
5. Overexpression of α-synuclein inhibits mitochondrial Ca Erustes AG; D'Eletto M; Guarache GC; Ureshino RP; Bincoletto C; da Silva Pereira GJ; Piacentini M; Smaili SS J Neurosci Res; 2021 Nov; 99(11):2932-2947. PubMed ID: 34510532 [TBL] [Abstract][Full Text] [Related]
6. Endoplasmic reticulum stress and mitochondrial cell death pathways mediate A53T mutant alpha-synuclein-induced toxicity. Smith WW; Jiang H; Pei Z; Tanaka Y; Morita H; Sawa A; Dawson VL; Dawson TM; Ross CA Hum Mol Genet; 2005 Dec; 14(24):3801-11. PubMed ID: 16239241 [TBL] [Abstract][Full Text] [Related]
8. α-Synuclein Overexpression Induces Lysosomal Dysfunction and Autophagy Impairment in Human Neuroblastoma SH-SY5Y. Nascimento AC; Erustes AG; Reckziegel P; Bincoletto C; Ureshino RP; Pereira GJS; Smaili SS Neurochem Res; 2020 Nov; 45(11):2749-2761. PubMed ID: 32915398 [TBL] [Abstract][Full Text] [Related]
9. Parkinson disease mutant E46K enhances α-synuclein phosphorylation in mammalian cell lines, in yeast, and in vivo. Mbefo MK; Fares MB; Paleologou K; Oueslati A; Yin G; Tenreiro S; Pinto M; Outeiro T; Zweckstetter M; Masliah E; Lashuel HA J Biol Chem; 2015 Apr; 290(15):9412-27. PubMed ID: 25657004 [TBL] [Abstract][Full Text] [Related]
10. Protective effect of TAT-delivered alpha-synuclein: relevance of the C-terminal domain and involvement of HSP70. Albani D; Peverelli E; Rametta R; Batelli S; Veschini L; Negro A; Forloni G FASEB J; 2004 Nov; 18(14):1713-5. PubMed ID: 15345691 [TBL] [Abstract][Full Text] [Related]
11. Differential regulation of wild-type and mutant alpha-synuclein binding to synaptic membranes by cytosolic factors. Wislet-Gendebien S; Visanji NP; Whitehead SN; Marsilio D; Hou W; Figeys D; Fraser PE; Bennett SA; Tandon A BMC Neurosci; 2008 Sep; 9():92. PubMed ID: 18808659 [TBL] [Abstract][Full Text] [Related]
12. α-Synuclein binds to the ER-mitochondria tethering protein VAPB to disrupt Ca Paillusson S; Gomez-Suaga P; Stoica R; Little D; Gissen P; Devine MJ; Noble W; Hanger DP; Miller CCJ Acta Neuropathol; 2017 Jul; 134(1):129-149. PubMed ID: 28337542 [TBL] [Abstract][Full Text] [Related]
13. Human A53T α-synuclein causes reversible deficits in mitochondrial function and dynamics in primary mouse cortical neurons. Li L; Nadanaciva S; Berger Z; Shen W; Paumier K; Schwartz J; Mou K; Loos P; Milici AJ; Dunlop J; Hirst WD PLoS One; 2013; 8(12):e85815. PubMed ID: 24392030 [TBL] [Abstract][Full Text] [Related]
14. A new role for α-synuclein in Parkinson's disease: Alteration of ER-mitochondrial communication. Guardia-Laguarta C; Area-Gomez E; Schon EA; Przedborski S Mov Disord; 2015 Jul; 30(8):1026-33. PubMed ID: 25952565 [TBL] [Abstract][Full Text] [Related]
15. Neuroprotection of α-synuclein under acute and chronic rotenone and maneb treatment is abolished by its familial Parkinson's disease mutations A30P, A53T and E46K. Choong CJ; Say YH Neurotoxicology; 2011 Dec; 32(6):857-63. PubMed ID: 21658409 [TBL] [Abstract][Full Text] [Related]
16. Alteration of Structure and Aggregation of α-Synuclein by Familial Parkinson's Disease Associated Mutations. Sahay S; Ghosh D; Singh PK; Maji SK Curr Protein Pept Sci; 2017; 18(7):656-676. PubMed ID: 26972727 [TBL] [Abstract][Full Text] [Related]
17. Defective membrane interactions of familial Parkinson's disease mutant A30P alpha-synuclein. Jo E; Fuller N; Rand RP; St George-Hyslop P; Fraser PE J Mol Biol; 2002 Jan; 315(4):799-807. PubMed ID: 11812148 [TBL] [Abstract][Full Text] [Related]
18. Impairment of mitochondria dynamics by human A53T α-synuclein and rescue by NAP (davunetide) in a cell model for Parkinson's disease. Melo TQ; van Zomeren KC; Ferrari MF; Boddeke HW; Copray JC Exp Brain Res; 2017 Mar; 235(3):731-742. PubMed ID: 27866262 [TBL] [Abstract][Full Text] [Related]
19. Generation of a alpha-synuclein-based rat model of Parkinson's disease. Recchia A; Rota D; Debetto P; Peroni D; Guidolin D; Negro A; Skaper SD; Giusti P Neurobiol Dis; 2008 Apr; 30(1):8-18. PubMed ID: 18313315 [TBL] [Abstract][Full Text] [Related]
20. Fibrillization of alpha-synuclein and tau in familial Parkinson's disease caused by the A53T alpha-synuclein mutation. Kotzbauer PT; Giasson BI; Kravitz AV; Golbe LI; Mark MH; Trojanowski JQ; Lee VM Exp Neurol; 2004 Jun; 187(2):279-88. PubMed ID: 15144854 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]