163 related articles for article (PubMed ID: 31554629)
1. Fluvastatin Inhibits HMG-CoA Reductase and Prevents Non-Small Cell Lung Carcinogenesis.
Zhang T; Bai R; Wang Q; Wang K; Li X; Liu K; Ryu J; Wang T; Chang X; Ma W; Bode AM; Xia Q; Song Y; Dong Z
Cancer Prev Res (Phila); 2019 Dec; 12(12):837-848. PubMed ID: 31554629
[TBL] [Abstract][Full Text] [Related]
2. An actionable sterol-regulated feedback loop modulates statin sensitivity in prostate cancer.
Longo J; Mullen PJ; Yu R; van Leeuwen JE; Masoomian M; Woon DTS; Wang Y; Chen EX; Hamilton RJ; Sweet JM; van der Kwast TH; Fleshner NE; Penn LZ
Mol Metab; 2019 Jul; 25():119-130. PubMed ID: 31023626
[TBL] [Abstract][Full Text] [Related]
3. The isomiR-140-3p-regulated mevalonic acid pathway as a potential target for prevention of triple negative breast cancer.
Bhardwaj A; Singh H; Trinidad CM; Albarracin CT; Hunt KK; Bedrosian I
Breast Cancer Res; 2018 Dec; 20(1):150. PubMed ID: 30537987
[TBL] [Abstract][Full Text] [Related]
4. Fluvastatin is effective against thymic carcinoma.
Hayashi K; Nakazato Y; Morito N; Sagi M; Fujita T; Anzai N; Chida M
Life Sci; 2020 Jan; 240():117110. PubMed ID: 31786191
[TBL] [Abstract][Full Text] [Related]
5. Genome-wide RNAi analysis reveals that simultaneous inhibition of specific mevalonate pathway genes potentiates tumor cell death.
Pandyra AA; Mullen PJ; Goard CA; Ericson E; Sharma P; Kalkat M; Yu R; Pong JT; Brown KR; Hart T; Gebbia M; Lang KS; Giaever G; Nislow C; Moffat J; Penn LZ
Oncotarget; 2015 Sep; 6(29):26909-21. PubMed ID: 26353928
[TBL] [Abstract][Full Text] [Related]
6. 3-hydroxy-3-methylglutaryl-coenzyme a reductase inhibitor, fluvastatin, as a novel agent for prophylaxis of renal cancer metastasis.
Horiguchi A; Sumitomo M; Asakuma J; Asano T; Asano T; Hayakawa M
Clin Cancer Res; 2004 Dec; 10(24):8648-55. PubMed ID: 15623649
[TBL] [Abstract][Full Text] [Related]
7. 3-hydroxy-3-methylglutaryl-coenzyme a reductase inhibitors reduce human pancreatic cancer cell invasion and metastasis.
Kusama T; Mukai M; Iwasaki T; Tatsuta M; Matsumoto Y; Akedo H; Inoue M; Nakamura H
Gastroenterology; 2002 Feb; 122(2):308-17. PubMed ID: 11832446
[TBL] [Abstract][Full Text] [Related]
8. Inhibition of Orbivirus Replication by Fluvastatin and Identification of the Key Elements of the Mevalonate Pathway Involved.
Mohd Jaafar F; Monsion B; Belhouchet M; Mertens PPC; Attoui H
Viruses; 2021 Jul; 13(8):. PubMed ID: 34452303
[TBL] [Abstract][Full Text] [Related]
9. Delineation of cell death mechanisms induced by synergistic effects of statins and erlotinib in non-small cell lung cancer cell (NSCLC) lines.
Otahal A; Aydemir D; Tomasich E; Minichsdorfer C
Sci Rep; 2020 Jan; 10(1):959. PubMed ID: 31969600
[TBL] [Abstract][Full Text] [Related]
10. Early embryonic lethality caused by targeted disruption of the 3-hydroxy-3-methylglutaryl-CoA reductase gene.
Ohashi K; Osuga J; Tozawa R; Kitamine T; Yagyu H; Sekiya M; Tomita S; Okazaki H; Tamura Y; Yahagi N; Iizuka Y; Harada K; Gotoda T; Shimano H; Yamada N; Ishibashi S
J Biol Chem; 2003 Oct; 278(44):42936-41. PubMed ID: 12920113
[TBL] [Abstract][Full Text] [Related]
11. Cucurbitacin B Alters the Expression of Tumor-Related Genes by Epigenetic Modifications in NSCLC and Inhibits NNK-Induced Lung Tumorigenesis.
Shukla S; Khan S; Kumar S; Sinha S; Farhan M; Bora HK; Maurya R; Meeran SM
Cancer Prev Res (Phila); 2015 Jun; 8(6):552-62. PubMed ID: 25813524
[TBL] [Abstract][Full Text] [Related]
12. BAI1 acts as a tumor suppressor in lung cancer A549 cells by inducing metabolic reprogramming via the SCD1/HMGCR module.
Liu L; Chai L; Ran J; Yang Y; Zhang L
Carcinogenesis; 2020 Dec; 41(12):1724-1734. PubMed ID: 32255478
[TBL] [Abstract][Full Text] [Related]
13. Overcoming statin resistance in prostate cancer cells by targeting the 3-hydroxy-3-methylglutaryl-CoA-reductase.
Göbel A; Pählig S; Motz A; Breining D; Traikov S; Hofbauer LC; Rachner TD
Biochem Biophys Res Commun; 2024 May; 710():149841. PubMed ID: 38588613
[TBL] [Abstract][Full Text] [Related]
14. The Mevalonate Pathway and Innate Immune Hyper-Responsiveness in the Pathogenesis of COPD and Lung Cancer: Potential for Chemoprevention.
Young RP; Hopkins RJ
Curr Mol Pharmacol; 2017; 10(1):46-59. PubMed ID: 26758944
[TBL] [Abstract][Full Text] [Related]
15. Proto oncogene/eukaryotic translation initiation factor (eIF) 4E attenuates mevalonate-mediated regulation of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase synthesis.
Buechler RD; Peffley DM
Mol Carcinog; 2004 Sep; 41(1):39-53. PubMed ID: 15352124
[TBL] [Abstract][Full Text] [Related]
16. The HMG-CoA reductase inhibitor, simvastatin, exhibits anti-metastatic and anti-tumorigenic effects in ovarian cancer.
Stine JE; Guo H; Sheng X; Han X; Schointuch MN; Gilliam TP; Gehrig PA; Zhou C; Bae-Jump VL
Oncotarget; 2016 Jan; 7(1):946-60. PubMed ID: 26503475
[TBL] [Abstract][Full Text] [Related]
17. Explication of interactions between HMGCR isoform 2 and various statins through In silico modeling and docking.
Karthik MV; Satya Deepak MV; Shukla P
Comput Biol Med; 2012 Feb; 42(2):156-63. PubMed ID: 22177940
[TBL] [Abstract][Full Text] [Related]
18. Mesenchymal subtype neuroblastomas are addicted to TGF-βR2/HMGCR-driven protein geranylgeranylation.
Stokes ME; Small JC; Vasciaveo A; Shimada K; Hirschhorn T; Califano A; Stockwell BR
Sci Rep; 2020 Jul; 10(1):10748. PubMed ID: 32612149
[TBL] [Abstract][Full Text] [Related]
19. Suppression by geraniol of the growth of A549 human lung adenocarcinoma cells and inhibition of the mevalonate pathway in culture and in vivo: potential use in cancer chemotherapy.
Galle M; Crespo R; Kladniew BR; Villegas SM; Polo M; de Bravo MG
Nutr Cancer; 2014; 66(5):888-95. PubMed ID: 24875281
[TBL] [Abstract][Full Text] [Related]
20. Induction of 3-hydroxy-3-methylglutaryl-CoA reductase mediates statin resistance in breast cancer cells.
Göbel A; Breining D; Rauner M; Hofbauer LC; Rachner TD
Cell Death Dis; 2019 Jan; 10(2):91. PubMed ID: 30692522
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
