These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

164 related articles for article (PubMed ID: 31554935)

  • 1. Therapeutic targeting of the PI4K2A/PKR lysosome network is critical for misfolded protein clearance and survival in cancer cells.
    Pataer A; Ozpolat B; Shao R; Cashman NR; Plotkin SS; Samuel CE; Lin SH; Kabil NN; Wang J; Majidi M; Fang B; Roth JA; Vaporciyan AA; Wistuba II; Hung MC; Swisher SG
    Oncogene; 2020 Jan; 39(4):801-813. PubMed ID: 31554935
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Mouse models for hereditary spastic paraplegia uncover a role of PI4K2A in autophagic lysosome reformation.
    Khundadze M; Ribaudo F; Hussain A; Stahlberg H; Brocke-Ahmadinejad N; Franzka P; Varga RE; Zarkovic M; Pungsrinont T; Kokal M; Ganley IG; Beetz C; Sylvester M; Hübner CA
    Autophagy; 2021 Nov; 17(11):3690-3706. PubMed ID: 33618608
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Clinical and therapeutic potential of protein kinase PKR in cancer and metabolism.
    Garcia-Ortega MB; Lopez GJ; Jimenez G; Garcia-Garcia JA; Conde V; Boulaiz H; Carrillo E; Perán M; Marchal JA; Garcia MA
    Expert Rev Mol Med; 2017 Jul; 19():e9. PubMed ID: 28724458
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Foot-and-mouth disease virus induces lysosomal degradation of host protein kinase PKR by 3C proteinase to facilitate virus replication.
    Li C; Zhu Z; Du X; Cao W; Yang F; Zhang X; Feng H; Li D; Zhang K; Liu X; Zheng H
    Virology; 2017 Sep; 509():222-231. PubMed ID: 28662438
    [TBL] [Abstract][Full Text] [Related]  

  • 5. An integrated stress response via PKR suppresses HER2+ cancers and improves trastuzumab therapy.
    Darini C; Ghaddar N; Chabot C; Assaker G; Sabri S; Wang S; Krishnamoorthy J; Buchanan M; Aguilar-Mahecha A; Abdulkarim B; Deschenes J; Torres J; Ursini-Siegel J; Basik M; Koromilas AE
    Nat Commun; 2019 May; 10(1):2139. PubMed ID: 31086176
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Comobility of GABARAP and Phosphatidylinositol 4-Kinase 2A on Cytoplasmic Vesicles.
    Chen Y; Sun HQ; Eichorst JP; Albanesi JP; Yin H; Mueller JD
    Biochemistry; 2018 Jul; 57(26):3556-3559. PubMed ID: 29792687
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Enhanced Replication of Mouse Adenovirus Type 1 following Virus-Induced Degradation of Protein Kinase R (PKR).
    Goodman DE; Pretto CD; Krepostman TA; Carnahan KE; Spindler KR
    mBio; 2019 Apr; 10(2):. PubMed ID: 31015330
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Multifunctional TPP-PEG-biotin self-assembled nanoparticle drug delivery-based combination therapeutic approach for co-targeting of GRP78 and lysosome.
    Purushothaman B; Lee J; Hong S; Song JM
    J Nanobiotechnology; 2020 Jul; 18(1):102. PubMed ID: 32690101
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Expression of the double-stranded RNA-dependent kinase PKR influences osteosarcoma attachment independent growth, migration, and invasion.
    Piazzi M; Bavelloni A; Greco S; Focaccia E; Orsini A; Benini S; Gambarotti M; Faenza I; Blalock WL
    J Cell Physiol; 2020 Feb; 235(2):1103-1119. PubMed ID: 31240713
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Dual induction of PKR with E2F-1 and IFN-alpha to enhance gene therapy against hepatocellular carcinoma.
    Roh V; Laemmle A; Von Holzen U; Stroka D; Dufour JF; Hunt KK; Candinas D; Vorburger SA
    Cancer Gene Ther; 2008 Oct; 15(10):636-44. PubMed ID: 18535617
    [TBL] [Abstract][Full Text] [Related]  

  • 11. RNA-dependent protein kinase (PKR) depletes nutrients, inducing phosphorylation of AMP-activated kinase in lung cancer.
    Guo C; Hao C; Shao R; Fang B; Correa AM; Hofstetter WL; Roth JA; Behrens C; Kalhor N; Wistuba II; Swisher SG; Pataer A
    Oncotarget; 2015 May; 6(13):11114-24. PubMed ID: 25798539
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Inhibition of PKR protects against tunicamycin-induced apoptosis in neuroblastoma cells.
    Vaughn LS; Snee B; Patel RC
    Gene; 2014 Feb; 536(1):90-6. PubMed ID: 24334130
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The protein activator of protein kinase R, PACT/RAX, negatively regulates protein kinase R during mouse anterior pituitary development.
    Dickerman BK; White CL; Kessler PM; Sadler AJ; Williams BR; Sen GC
    FEBS J; 2015 Dec; 282(24):4766-81. PubMed ID: 26414443
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Therapeutic effects of the PKR inhibitor C16 suppressing tumor proliferation and angiogenesis in hepatocellular carcinoma in vitro and in vivo.
    Watanabe T; Ninomiya H; Saitou T; Takanezawa S; Yamamoto S; Imai Y; Yoshida O; Kawakami R; Hirooka M; Abe M; Imamura T; Hiasa Y
    Sci Rep; 2020 Mar; 10(1):5133. PubMed ID: 32198380
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Genetically targeted cancer therapy: tumor destruction by PKR activation.
    Vorburger SA; Pataer A; Swisher SG; Hunt KK
    Am J Pharmacogenomics; 2004; 4(3):189-98. PubMed ID: 15174900
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Bortezomib inhibits PKR-like endoplasmic reticulum (ER) kinase and induces apoptosis via ER stress in human pancreatic cancer cells.
    Nawrocki ST; Carew JS; Dunner K; Boise LH; Chiao PJ; Huang P; Abbruzzese JL; McConkey DJ
    Cancer Res; 2005 Dec; 65(24):11510-9. PubMed ID: 16357160
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Blockade of the LRP16-PKR-NF-κB signaling axis sensitizes colorectal carcinoma cells to DNA-damaging cytotoxic therapy.
    Li X; Wu Z; An X; Mei Q; Bai M; Hanski L; Li X; Ahola T; Han W
    Elife; 2017 Aug; 6():. PubMed ID: 28820388
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Accumulation of RNA-dependent protein kinase (PKR) in the nuclei of lung cancer cells mediates radiation resistance.
    Hao C; Shao R; Raju U; Fang B; Swisher SG; Pataer A
    Oncotarget; 2016 Jun; 7(25):38235-38242. PubMed ID: 27203671
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Influenza A Virus Virulence Depends on Two Amino Acids in the N-Terminal Domain of Its NS1 Protein To Facilitate Inhibition of the RNA-Dependent Protein Kinase PKR.
    Schierhorn KL; Jolmes F; Bespalowa J; Saenger S; Peteranderl C; Dzieciolowski J; Mielke M; Budt M; Pleschka S; Herrmann A; Herold S; Wolff T
    J Virol; 2017 May; 91(10):. PubMed ID: 28250123
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Heat Shock Protein 47 Maintains Cancer Cell Growth by Inhibiting the Unfolded Protein Response Transducer IRE1α.
    Yoneda A; Sakai-Sawada K; Minomi K; Tamura Y
    Mol Cancer Res; 2020 Jun; 18(6):847-858. PubMed ID: 32102897
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.