BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

293 related articles for article (PubMed ID: 31560043)

  • 1. Tofacitinib Reprograms Human Monocytes of IBD Patients and Healthy Controls Toward a More Regulatory Phenotype.
    Cordes F; Lenker E; Spille LJ; Weinhage T; Bettenworth D; Kessel C; Schmidt HH; Foell D; Varga G
    Inflamm Bowel Dis; 2020 Feb; 26(3):391-406. PubMed ID: 31560043
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Impaired IFN-γ-dependent STAT3 Activation Is Associated With Dysregulation of Regulatory and Inflammatory Signaling in Monocytes of Ulcerative Colitis Patients.
    Cordes F; Lenker E; Weinhage T; Spille LJ; Bettenworth D; Varga G; Schmidt HH; Foell D
    Inflamm Bowel Dis; 2021 May; 27(6):887-901. PubMed ID: 33165509
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Tofacitinib inhibits granulocyte-macrophage colony-stimulating factor-induced NLRP3 inflammasome activation in human neutrophils.
    Furuya MY; Asano T; Sumichika Y; Sato S; Kobayashi H; Watanabe H; Suzuki E; Kozuru H; Yatsuhashi H; Koga T; Ohira H; Sekine H; Kawakami A; Migita K
    Arthritis Res Ther; 2018 Aug; 20(1):196. PubMed ID: 30157949
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Involvement of JAK/STAT signaling in the pathogenesis of inflammatory bowel disease.
    Coskun M; Salem M; Pedersen J; Nielsen OH
    Pharmacol Res; 2013 Oct; 76():1-8. PubMed ID: 23827161
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Comparison of baricitinib, upadacitinib, and tofacitinib mediated regulation of cytokine signaling in human leukocyte subpopulations.
    McInnes IB; Byers NL; Higgs RE; Lee J; Macias WL; Na S; Ortmann RA; Rocha G; Rooney TP; Wehrman T; Zhang X; Zuckerman SH; Taylor PC
    Arthritis Res Ther; 2019 Aug; 21(1):183. PubMed ID: 31375130
    [TBL] [Abstract][Full Text] [Related]  

  • 6. A JAK1 Selective Kinase Inhibitor and Tofacitinib Affect Macrophage Activation and Function.
    De Vries LCS; Duarte JM; De Krijger M; Welting O; Van Hamersveld PHP; Van Leeuwen-Hilbers FWM; Moerland PD; Jongejan A; D'Haens GR; De Jonge WJ; Wildenberg ME
    Inflamm Bowel Dis; 2019 Mar; 25(4):647-660. PubMed ID: 30668755
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Tofacitinib Suppresses Several JAK-STAT Pathways in Rheumatoid Arthritis
    Palmroth M; Kuuliala K; Peltomaa R; Virtanen A; Kuuliala A; Kurttila A; Kinnunen A; Leirisalo-Repo M; Silvennoinen O; Isomäki P
    Front Immunol; 2021; 12():738481. PubMed ID: 34630419
    [TBL] [Abstract][Full Text] [Related]  

  • 8. JAK inhibition using tofacitinib for inflammatory bowel disease treatment: a hub for multiple inflammatory cytokines.
    Danese S; Grisham M; Hodge J; Telliez JB
    Am J Physiol Gastrointest Liver Physiol; 2016 Feb; 310(3):G155-62. PubMed ID: 26608188
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Janus kinase inhibitors prevent migration of rheumatoid arthritis neutrophils towards interleukin-8, but do not inhibit priming of the respiratory burst or reactive oxygen species production.
    Mitchell TS; Moots RJ; Wright HL
    Clin Exp Immunol; 2017 Aug; 189(2):250-258. PubMed ID: 28369741
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Granulocyte Macrophage Colony-Stimulating Factor-Activated CD39
    Weinhage T; Däbritz J; Brockhausen A; Wirth T; Brückner M; Belz M; Foell D; Varga G
    Cell Mol Gastroenterol Hepatol; 2015 Jul; 1(4):433-449.e1. PubMed ID: 28210690
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Tofacitinib inhibits inflammatory cytokines from ulcerative colitis and healthy mucosal explants and is associated with pSTAT1/3 reduction in T-cells.
    Brand RM; Moore BA; Zyhowski A; Siegel A; Uttam S; Metter EJ; Engstrom J; Brand RE; Biswas N; Whitcomb DC; Binion DG; Schwartz M; McGowan I
    Am J Physiol Gastrointest Liver Physiol; 2021 Mar; 320(3):G396-G410. PubMed ID: 33355506
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The Janus Kinase inhibitor tofacitinib impacts human dendritic cell differentiation and favours M1 macrophage development.
    Stalder R; Zhang B; Jean Wrobel L; Boehncke WH; Brembilla NC
    Exp Dermatol; 2020 Jan; 29(1):71-78. PubMed ID: 31721311
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Tofacitinib Affects M1-like and M2-like Polarization and Tissue Factor Expression in Macrophages of Healthy Donors and IBD Patients.
    Lethen I; Lechner-Grimm K; Gabel M; Knauss A; Atreya R; Neurath MF; Weigmann B
    Inflamm Bowel Dis; 2023 Dec; ():. PubMed ID: 38142236
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Tofacitinib ameliorates inflammation in a rat model of airway neutrophilia induced by inhaled LPS.
    Calama E; Ramis I; Domènech A; Carreño C; De Alba J; Prats N; Miralpeix M
    Pulm Pharmacol Ther; 2017 Apr; 43():60-67. PubMed ID: 28087469
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Tofacitinib regulates synovial inflammation in psoriatic arthritis, inhibiting STAT activation and induction of negative feedback inhibitors.
    Gao W; McGarry T; Orr C; McCormick J; Veale DJ; Fearon U
    Ann Rheum Dis; 2016 Jan; 75(1):311-5. PubMed ID: 26353790
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Tofacitinib for the treatment of ulcerative colitis.
    Izzo R; Bevivino G; Monteleone G
    Expert Opin Investig Drugs; 2016 Aug; 25(8):991-7. PubMed ID: 27177233
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The JAK-Inhibitor Tofacitinib Rescues Human Intestinal Epithelial Cells and Colonoids from Cytokine-Induced Barrier Dysfunction.
    Sayoc-Becerra A; Krishnan M; Fan S; Jimenez J; Hernandez R; Gibson K; Preciado R; Butt G; McCole DF
    Inflamm Bowel Dis; 2020 Feb; 26(3):407-422. PubMed ID: 31751457
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Selective JAK/STAT3 signalling regulates transcription of colony stimulating factor-2 and -3 in Concanavalin-A-activated mesenchymal stromal cells.
    Zgheib A; Pelletier-Bonnier É; Levros LC; Annabi B
    Cytokine; 2013 Aug; 63(2):187-93. PubMed ID: 23688618
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The JAK inhibitor, tofacitinib, reduces the T cell stimulatory capacity of human monocyte-derived dendritic cells.
    Kubo S; Yamaoka K; Kondo M; Yamagata K; Zhao J; Iwata S; Tanaka Y
    Ann Rheum Dis; 2014 Dec; 73(12):2192-8. PubMed ID: 24013646
    [TBL] [Abstract][Full Text] [Related]  

  • 20. JAK inhibitors impair GM-CSF-mediated signaling in innate immune cells.
    Fujita Y; Matsuoka N; Temmoku J; Furuya-Yashiro M; Asano T; Sato S; Matsumoto H; Watanabe H; Kozuru H; Yatsuhashi H; Kawakami A; Migita K
    BMC Immunol; 2020 Jun; 21(1):35. PubMed ID: 32539713
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.