BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

319 related articles for article (PubMed ID: 31560342)

  • 1. A new class of disordered elements controls DNA replication through initiator self-assembly.
    Parker MW; Bell M; Mir M; Kao JA; Darzacq X; Botchan MR; Berger JM
    Elife; 2019 Sep; 8():. PubMed ID: 31560342
    [TBL] [Abstract][Full Text] [Related]  

  • 2. A helicase-tethered ORC flip enables bidirectional helicase loading.
    Gupta S; Friedman LJ; Gelles J; Bell SP
    Elife; 2021 Dec; 10():. PubMed ID: 34882090
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Structural mechanism of helicase loading onto replication origin DNA by ORC-Cdc6.
    Yuan Z; Schneider S; Dodd T; Riera A; Bai L; Yan C; Magdalou I; Ivanov I; Stillman B; Li H; Speck C
    Proc Natl Acad Sci U S A; 2020 Jul; 117(30):17747-17756. PubMed ID: 32669428
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Regulation of replication origin licensing by ORC phosphorylation reveals a two-step mechanism for Mcm2-7 ring closing.
    Amasino AL; Gupta S; Friedman LJ; Gelles J; Bell SP
    Proc Natl Acad Sci U S A; 2023 Jul; 120(29):e2221484120. PubMed ID: 37428921
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Structural mechanism for replication origin binding and remodeling by a metazoan origin recognition complex and its co-loader Cdc6.
    Schmidt JM; Bleichert F
    Nat Commun; 2020 Aug; 11(1):4263. PubMed ID: 32848132
    [TBL] [Abstract][Full Text] [Related]  

  • 6. An ORC/Cdc6/MCM2-7 complex is formed in a multistep reaction to serve as a platform for MCM double-hexamer assembly.
    Fernández-Cid A; Riera A; Tognetti S; Herrera MC; Samel S; Evrin C; Winkler C; Gardenal E; Uhle S; Speck C
    Mol Cell; 2013 May; 50(4):577-88. PubMed ID: 23603117
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Mechanisms and regulation of DNA replication initiation in eukaryotes.
    Parker MW; Botchan MR; Berger JM
    Crit Rev Biochem Mol Biol; 2017 Apr; 52(2):107-144. PubMed ID: 28094588
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The ORC/Cdc6/MCM2-7 complex facilitates MCM2-7 dimerization during prereplicative complex formation.
    Evrin C; Fernández-Cid A; Riera A; Zech J; Clarke P; Herrera MC; Tognetti S; Lurz R; Speck C
    Nucleic Acids Res; 2014 Feb; 42(4):2257-69. PubMed ID: 24234446
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Sequential ATP hydrolysis by Cdc6 and ORC directs loading of the Mcm2-7 helicase.
    Randell JC; Bowers JL; Rodríguez HK; Bell SP
    Mol Cell; 2006 Jan; 21(1):29-39. PubMed ID: 16387651
    [TBL] [Abstract][Full Text] [Related]  

  • 10. A mechanism of origin licensing control through autoinhibition of S. cerevisiae ORC·DNA·Cdc6.
    Schmidt JM; Yang R; Kumar A; Hunker O; Seebacher J; Bleichert F
    Nat Commun; 2022 Feb; 13(1):1059. PubMed ID: 35217664
    [TBL] [Abstract][Full Text] [Related]  

  • 11. In the absence of ATPase activity, pre-RC formation is blocked prior to MCM2-7 hexamer dimerization.
    Evrin C; Fernández-Cid A; Zech J; Herrera MC; Riera A; Clarke P; Brill S; Lurz R; Speck C
    Nucleic Acids Res; 2013 Mar; 41(5):3162-72. PubMed ID: 23376927
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Structural basis of Mcm2-7 replicative helicase loading by ORC-Cdc6 and Cdt1.
    Yuan Z; Riera A; Bai L; Sun J; Nandi S; Spanos C; Chen ZA; Barbon M; Rappsilber J; Stillman B; Speck C; Li H
    Nat Struct Mol Biol; 2017 Mar; 24(3):316-324. PubMed ID: 28191893
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Molecular determinants of phase separation for
    Parker MW; Kao JA; Huang A; Berger JM; Botchan MR
    Elife; 2021 Dec; 10():. PubMed ID: 34951585
    [TBL] [Abstract][Full Text] [Related]  

  • 14. MCM interference during licensing of DNA replication in Xenopus egg extracts-Possible Role of a C-terminal region of MCM3.
    Mimura S; Kubota Y; Takisawa H
    Cell Cycle; 2018; 17(4):492-505. PubMed ID: 29261034
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Conformational control and DNA-binding mechanism of the metazoan origin recognition complex.
    Bleichert F; Leitner A; Aebersold R; Botchan MR; Berger JM
    Proc Natl Acad Sci U S A; 2018 Jun; 115(26):E5906-E5915. PubMed ID: 29899147
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Dynamics of DNA binding of replication initiation proteins during de novo formation of pre-replicative complexes in Xenopus egg extracts.
    Waga S; Zembutsu A
    J Biol Chem; 2006 Apr; 281(16):10926-34. PubMed ID: 16497662
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The structure of ORC-Cdc6 on an origin DNA reveals the mechanism of ORC activation by the replication initiator Cdc6.
    Feng X; Noguchi Y; Barbon M; Stillman B; Speck C; Li H
    Nat Commun; 2021 Jun; 12(1):3883. PubMed ID: 34162887
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Cryo-EM structure of a helicase loading intermediate containing ORC-Cdc6-Cdt1-MCM2-7 bound to DNA.
    Sun J; Evrin C; Samel SA; Fernández-Cid A; Riera A; Kawakami H; Stillman B; Speck C; Li H
    Nat Struct Mol Biol; 2013 Aug; 20(8):944-51. PubMed ID: 23851460
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Changing protein-DNA interactions promote ORC binding-site exchange during replication origin licensing.
    Zhang A; Friedman LJ; Gelles J; Bell SP
    Proc Natl Acad Sci U S A; 2023 Jul; 120(30):e2305556120. PubMed ID: 37463200
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Single-Molecule Visualization of MCM2-7 DNA Loading: Seeing Is Believing.
    Chistol G; Walter JC
    Cell; 2015 Apr; 161(3):429-430. PubMed ID: 25910200
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 16.