BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

255 related articles for article (PubMed ID: 31561108)

  • 1. Novel pyridazinone derivatives as butyrylcholinesterase inhibitors.
    Dundar Y; Kuyrukcu O; Eren G; Senol Deniz FS; Onkol T; Orhan IE
    Bioorg Chem; 2019 Nov; 92():103304. PubMed ID: 31561108
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Cyanobiphenyls: Novel H
    Godyń J; Zaręba P; Łażewska D; Stary D; Reiner-Link D; Frank A; Latacz G; Mogilski S; Kaleta M; Doroz-Płonka A; Lubelska A; Honkisz-Orzechowska E; Olejarz-Maciej A; Handzlik J; Stark H; Kieć-Kononowicz K; Malawska B; Bajda M
    Bioorg Chem; 2021 Sep; 114():105129. PubMed ID: 34217977
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Phenoxyethyl Piperidine/Morpholine Derivatives as PAS and CAS Inhibitors of Cholinesterases: Insights for Future Drug Design.
    Pourshojaei Y; Abiri A; Eskandari K; Haghighijoo Z; Edraki N; Asadipour A
    Sci Rep; 2019 Dec; 9(1):19855. PubMed ID: 31882733
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Synthesis and evaluation of multi-target-directed ligands for the treatment of Alzheimer's disease based on the fusion of donepezil and melatonin.
    Wang J; Wang ZM; Li XM; Li F; Wu JJ; Kong LY; Wang XB
    Bioorg Med Chem; 2016 Sep; 24(18):4324-4338. PubMed ID: 27460699
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Design and synthesis of some new carboxamide and propanamide derivatives bearing phenylpyridazine as a core ring and the investigation of their inhibitory potential on in-vitro acetylcholinesterase and butyrylcholinesterase.
    Kilic B; Gulcan HO; Aksakal F; Ercetin T; Oruklu N; Umit Bagriacik E; Dogruer DS
    Bioorg Chem; 2018 Sep; 79():235-249. PubMed ID: 29775949
    [TBL] [Abstract][Full Text] [Related]  

  • 6. New cholinesterase inhibitors for Alzheimer's disease: Structure Activity Studies (SARs) and molecular docking of isoquinolone and azepanone derivatives.
    Bacalhau P; San Juan AA; Marques CS; Peixoto D; Goth A; Guarda C; Silva M; Arantes S; Caldeira AT; Martins R; Burke AJ
    Bioorg Chem; 2016 Aug; 67():1-8. PubMed ID: 27231829
    [TBL] [Abstract][Full Text] [Related]  

  • 7. 7-MEOTA-donepezil like compounds as cholinesterase inhibitors: Synthesis, pharmacological evaluation, molecular modeling and QSAR studies.
    Korabecny J; Dolezal R; Cabelova P; Horova A; Hruba E; Ricny J; Sedlacek L; Nepovimova E; Spilovska K; Andrs M; Musilek K; Opletalova V; Sepsova V; Ripova D; Kuca K
    Eur J Med Chem; 2014 Jul; 82():426-38. PubMed ID: 24929293
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Design, Synthesis and Investigation of New Diphenyl Substituted Pyridazinone Derivatives as Both Cholinesterase and Aβ-Aggregation Inhibitors.
    Kilic B; Erdogan M; Gulcan HO; Aksakal F; Oruklu N; Bagriacik EU; Dogruer DS
    Med Chem; 2019; 15(1):59-76. PubMed ID: 29792155
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Multipotent cholinesterase/monoamine oxidase inhibitors for the treatment of Alzheimer's disease: design, synthesis, biochemical evaluation, ADMET, molecular modeling, and QSAR analysis of novel donepezil-pyridyl hybrids.
    Bautista-Aguilera OM; Esteban G; Chioua M; Nikolic K; Agbaba D; Moraleda I; Iriepa I; Soriano E; Samadi A; Unzeta M; Marco-Contelles J
    Drug Des Devel Ther; 2014; 8():1893-910. PubMed ID: 25378907
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Active compounds from a diverse library of triazolothiadiazole and triazolothiadiazine scaffolds: synthesis, crystal structure determination, cytotoxicity, cholinesterase inhibitory activity, and binding mode analysis.
    Khan I; Ibrar A; Zaib S; Ahmad S; Furtmann N; Hameed S; Simpson J; Bajorath J; Iqbal J
    Bioorg Med Chem; 2014 Nov; 22(21):6163-73. PubMed ID: 25257911
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Synthesis of novel 6-substituted-3(2H)-pyridazinone-2-acetyl-2-(substituted/-nonsubstituted benzal)hydrazone derivatives and acetylcholinesterase and butyrylcholinesterase inhibitory activities in vitro.
    Utku S; Gökçe M; Orhan I; Sahin MF
    Arzneimittelforschung; 2011; 61(1):1-7. PubMed ID: 21355440
    [TBL] [Abstract][Full Text] [Related]  

  • 12. N-1,2,3-triazole-isatin derivatives for cholinesterase and β-amyloid aggregation inhibition: A comprehensive bioassay study.
    Marques CS; López Ó; Bagetta D; Carreiro EP; Petralla S; Bartolini M; Hoffmann M; Alcaro S; Monti B; Bolognesi ML; Decker M; Fernández-Bolaños JG; Burke AJ
    Bioorg Chem; 2020 May; 98():103753. PubMed ID: 32200328
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Discovery of novel 2,6-disubstituted pyridazinone derivatives as acetylcholinesterase inhibitors.
    Xing W; Fu Y; Shi Z; Lu D; Zhang H; Hu Y
    Eur J Med Chem; 2013 May; 63():95-103. PubMed ID: 23466605
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Synthesis and pharmacological evaluation of donepezil-based agents as new cholinesterase/monoamine oxidase inhibitors for the potential application against Alzheimer's disease.
    Li F; Wang ZM; Wu JJ; Wang J; Xie SS; Lan JS; Xu W; Kong LY; Wang XB
    J Enzyme Inhib Med Chem; 2016; 31(sup3):41-53. PubMed ID: 27384289
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Novel chromanone-dithiocarbamate hybrids as multifunctional AChE inhibitors with β-amyloid anti-aggregation properties for the treatment of Alzheimer's disease.
    Jiang N; Ding J; Liu J; Sun X; Zhang Z; Mo Z; Li X; Yin H; Tang W; Xie SS
    Bioorg Chem; 2019 Aug; 89():103027. PubMed ID: 31176237
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Synthesis, pharmacology and molecular docking on multifunctional tacrine-ferulic acid hybrids as cholinesterase inhibitors against Alzheimer's disease.
    Zhu J; Yang H; Chen Y; Lin H; Li Q; Mo J; Bian Y; Pei Y; Sun H
    J Enzyme Inhib Med Chem; 2018 Dec; 33(1):496-506. PubMed ID: 29405075
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Synthesis and evaluation of 4-substituted coumarins as novel acetylcholinesterase inhibitors.
    Razavi SF; Khoobi M; Nadri H; Sakhteman A; Moradi A; Emami S; Foroumadi A; Shafiee A
    Eur J Med Chem; 2013 Jun; 64():252-9. PubMed ID: 23644208
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Tricyclic pyrazolo[1,5-d][1,4]benzoxazepin-5(6H)-one scaffold derivatives: Synthesis and biological evaluation as selective BuChE inhibitors.
    Chen SC; Qiu GL; Li B; Shi JB; Liu XH; Tang WJ
    Eur J Med Chem; 2018 Mar; 147():194-204. PubMed ID: 29438888
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Design, synthesis and biological activity of novel tacrine-isatin Schiff base hybrid derivatives.
    Riazimontazer E; Sadeghpour H; Nadri H; Sakhteman A; Tüylü Küçükkılınç T; Miri R; Edraki N
    Bioorg Chem; 2019 Aug; 89():103006. PubMed ID: 31158577
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Synthesis and characterization of new inhibitors of cholinesterases based on N-phenylcarbamates: In vitro study of inhibitory effect, type of inhibition, lipophilicity and molecular docking.
    Vorčáková K; Májeková M; Horáková E; Drabina P; Sedlák M; Štěpánková Š
    Bioorg Chem; 2018 Aug; 78():280-289. PubMed ID: 29621640
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.