BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

188 related articles for article (PubMed ID: 31569370)

  • 21. Finding significance: New perspectives in variant classification of the RAD51 regulators, BRCA2 and beyond.
    Rein HL; Bernstein KA
    DNA Repair (Amst); 2023 Oct; 130():103563. PubMed ID: 37651978
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Two Missense Variants Detected in Breast Cancer Probands Preventing BRCA2-PALB2 Protein Interaction.
    Caleca L; Catucci I; Figlioli G; De Cecco L; Pesaran T; Ward M; Volorio S; Falanga A; Marchetti M; Iascone M; Tondini C; Zambelli A; Azzollini J; Manoukian S; Radice P; Peterlongo P
    Front Oncol; 2018; 8():480. PubMed ID: 30410870
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Distinct roles of BRCA2 in replication fork protection in response to hydroxyurea and DNA interstrand cross-links.
    Rickman KA; Noonan RJ; Lach FP; Sridhar S; Wang AT; Abhyankar A; Huang A; Kelly M; Auerbach AD; Smogorzewska A
    Genes Dev; 2020 Jun; 34(11-12):832-846. PubMed ID: 32354836
    [TBL] [Abstract][Full Text] [Related]  

  • 24. DNA repair-related functional assays for the classification of BRCA1 and BRCA2 variants: a critical review and needs assessment.
    Toland AE; Andreassen PR
    J Med Genet; 2017 Nov; 54(11):721-731. PubMed ID: 28866612
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Evaluation of conformational transitions of h-BRCA2 functional domain and unclassified variant Arg2502Cys using multimodal approach.
    Khan MA; Siddiqui MQ; Kuligina E; Varma AK
    Int J Biol Macromol; 2022 Jun; 209(Pt A):716-724. PubMed ID: 35413318
    [TBL] [Abstract][Full Text] [Related]  

  • 26. The RAD52 S346X variant reduces risk of developing breast cancer in carriers of pathogenic germline BRCA2 mutations.
    Adamson AW; Ding YC; Mendez-Dorantes C; Bailis AM; Stark JM; Neuhausen SL
    Mol Oncol; 2020 Jun; 14(6):1124-1133. PubMed ID: 32175645
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Next Generation Sequencing Reveals High Prevalence of BRCA1 and BRCA2 Variants of Unknown Significance in Early-Onset Breast Cancer in African American Women.
    Ricks-Santi L; McDonald JT; Gold B; Dean M; Thompson N; Abbas M; Wilson B; Kanaan Y; Naab TJ; Dunston G
    Ethn Dis; 2017; 27(2):169-178. PubMed ID: 28439188
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Functional analyses of rare germline BRCA1 variants by transcriptional activation and homologous recombination repair assays.
    Bassi N; Hovland HN; Rasheed K; Jarhelle E; Pedersen N; Mchaina EK; Bakkan SME; Iversen N; Høberg-Vetti H; Haukanes BI; Knappskog PM; Aukrust I; Ognedal E; Van Ghelue M
    BMC Cancer; 2023 Apr; 23(1):368. PubMed ID: 37085799
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Functional evaluation of BRCA2 variants mapping to the PALB2-binding and C-terminal DNA-binding domains using a mouse ES cell-based assay.
    Biswas K; Das R; Eggington JM; Qiao H; North SL; Stauffer S; Burkett SS; Martin BK; Southon E; Sizemore SC; Pruss D; Bowles KR; Roa BB; Hunter N; Tessarollo L; Wenstrup RJ; Byrd RA; Sharan SK
    Hum Mol Genet; 2012 Sep; 21(18):3993-4006. PubMed ID: 22678057
    [TBL] [Abstract][Full Text] [Related]  

  • 30. RAD51C germline mutations in breast and ovarian cancer cases from high-risk families.
    Clague J; Wilhoite G; Adamson A; Bailis A; Weitzel JN; Neuhausen SL
    PLoS One; 2011; 6(9):e25632. PubMed ID: 21980511
    [TBL] [Abstract][Full Text] [Related]  

  • 31. In silico, in vitro and case-control analyses as an effective combination for analyzing BRCA1 and BRCA2 unclassified variants in a population-based sample.
    Rodríguez-Balada M; Roig B; Martorell L; Melé M; Salvat M; Vilella E; Borràs J; Gumà J
    Cancer Genet; 2016 Nov; 209(11):487-492. PubMed ID: 27886673
    [TBL] [Abstract][Full Text] [Related]  

  • 32.
    Concolino P; Gelli G; Rizza R; Costella A; Scambia G; Capoluongo E
    Int J Mol Sci; 2019 Jul; 20(14):. PubMed ID: 31336956
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Systematic misclassification of missense variants in BRCA1 and BRCA2 "coldspots".
    Dines JN; Shirts BH; Slavin TP; Walsh T; King MC; Fowler DM; Pritchard CC
    Genet Med; 2020 May; 22(5):825-830. PubMed ID: 31911673
    [TBL] [Abstract][Full Text] [Related]  

  • 34. ABRAXAS1 orchestrates BRCA1 activities to counter genome destabilizing repair pathways-lessons from breast cancer patients.
    Sachsenweger J; Jansche R; Merk T; Heitmeir B; Deniz M; Faust U; Roggia C; Tzschach A; Schroeder C; Riess A; Pospiech H; Peltoketo H; Pylkäs K; Winqvist R; Wiesmüller L
    Cell Death Dis; 2023 May; 14(5):328. PubMed ID: 37198153
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Analysis of BRCA1/2 variants of unknown significance in the prospective Korean Hereditary Breast Cancer study.
    Kim JH; Park S; Park HS; Park JS; Lee ST; Kim SW; Lee JW; Lee MH; Park SK; Noh WC; Choi DH; Han W; Jung SH
    Sci Rep; 2021 Apr; 11(1):8485. PubMed ID: 33875706
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Mis-splicing in breast cancer: identification of pathogenic BRCA2 variants by systematic minigene assays.
    Fraile-Bethencourt E; Valenzuela-Palomo A; Díez-Gómez B; Goina E; Acedo A; Buratti E; Velasco EA
    J Pathol; 2019 Aug; 248(4):409-420. PubMed ID: 30883759
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Prevalence and Spectrum of
    Foglietta J; Ludovini V; Bianconi F; Pistola L; Reda MS; Al-Refaie A; Tofanetti FR; Mosconi A; Minenza E; Anastasi P; Molica C; Stracci F; Roila F
    Genes (Basel); 2020 Aug; 11(8):. PubMed ID: 32806537
    [TBL] [Abstract][Full Text] [Related]  

  • 38. The BRCA2 homologue Brh2 nucleates RAD51 filament formation at a dsDNA-ssDNA junction.
    Yang H; Li Q; Fan J; Holloman WK; Pavletich NP
    Nature; 2005 Feb; 433(7026):653-7. PubMed ID: 15703751
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Challenges in periodic revision of genetic testing results: Comparison of the main classification guidelines and report of a retrospective analysis involving BRCA1/BRCA2 variants of uncertain significance.
    Andreis TF; de Souza KIW; Vieira IA; Alemar B; Sinigaglia M; de Araújo Rocha YM; Artigalás O; Bittar C; Oliveira Netto CB; Ashton-Prolla P; Rosset C
    Gene; 2023 Apr; 862():147281. PubMed ID: 36775216
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Hereditary breast and ovarian cancer: assessment of point mutations and copy number variations in Brazilian patients.
    Silva FC; Lisboa BC; Figueiredo MC; Torrezan GT; Santos EM; Krepischi AC; Rossi BM; Achatz MI; Carraro DM
    BMC Med Genet; 2014 May; 15():55. PubMed ID: 24884479
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 10.