BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

158 related articles for article (PubMed ID: 31569643)

  • 1. Promutagenicity of 8-Chloroguanine, A Major Inflammation-Induced Halogenated DNA Lesion.
    Kou Y; Koag MC; Lee S
    Molecules; 2019 Sep; 24(19):. PubMed ID: 31569643
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Structural basis for promutagenicity of 8-halogenated guanine.
    Koag MC; Min K; Lee S
    J Biol Chem; 2014 Feb; 289(9):6289-98. PubMed ID: 24425881
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Uncovering the polymerase-induced cytotoxicity of an oxidized nucleotide.
    Freudenthal BD; Beard WA; Perera L; Shock DD; Kim T; Schlick T; Wilson SH
    Nature; 2015 Jan; 517(7536):635-9. PubMed ID: 25409153
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Metal-dependent conformational activation explains highly promutagenic replication across O6-methylguanine by human DNA polymerase β.
    Koag MC; Lee S
    J Am Chem Soc; 2014 Apr; 136(15):5709-21. PubMed ID: 24694247
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Evading the proofreading machinery of a replicative DNA polymerase: induction of a mutation by an environmental carcinogen.
    Perlow RA; Broyde S
    J Mol Biol; 2001 Jun; 309(2):519-36. PubMed ID: 11371169
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Mutagenic Replication of the Major Oxidative Adenine Lesion 7,8-Dihydro-8-oxoadenine by Human DNA Polymerases.
    Koag MC; Jung H; Lee S
    J Am Chem Soc; 2019 Mar; 141(11):4584-4596. PubMed ID: 30817143
    [TBL] [Abstract][Full Text] [Related]  

  • 7. DNA polymerase minor groove interactions modulate mutagenic bypass of a templating 8-oxoguanine lesion.
    Freudenthal BD; Beard WA; Wilson SH
    Nucleic Acids Res; 2013 Feb; 41(3):1848-58. PubMed ID: 23267011
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Structural basis for proficient incorporation of dTTP opposite O6-methylguanine by human DNA polymerase iota.
    Pence MG; Choi JY; Egli M; Guengerich FP
    J Biol Chem; 2010 Dec; 285(52):40666-72. PubMed ID: 20961860
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Promutagenic bypass of 7,8-dihydro-8-oxoadenine by translesion synthesis DNA polymerase Dpo4.
    Jung H; Lee S
    Biochem J; 2020 Aug; 477(15):2859-2871. PubMed ID: 32686822
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Structural and Kinetic Studies of the Effect of Guanine N7 Alkylation and Metal Cofactors on DNA Replication.
    Kou Y; Koag MC; Lee S
    Biochemistry; 2018 Aug; 57(34):5105-5116. PubMed ID: 29957995
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Binary complex crystal structure of DNA polymerase β reveals multiple conformations of the templating 8-oxoguanine lesion.
    Batra VK; Shock DD; Beard WA; McKenna CE; Wilson SH
    Proc Natl Acad Sci U S A; 2012 Jan; 109(1):113-8. PubMed ID: 22178760
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Transition-state destabilization reveals how human DNA polymerase β proceeds across the chemically unstable lesion N7-methylguanine.
    Koag MC; Kou Y; Ouzon-Shubeita H; Lee S
    Nucleic Acids Res; 2014 Jul; 42(13):8755-66. PubMed ID: 24966350
    [TBL] [Abstract][Full Text] [Related]  

  • 13. DNA polymerase structure-based insight on the mutagenic properties of 8-oxoguanine.
    Beard WA; Batra VK; Wilson SH
    Mutat Res; 2010 Nov; 703(1):18-23. PubMed ID: 20696268
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Unique active site promotes error-free replication opposite an 8-oxo-guanine lesion by human DNA polymerase iota.
    Kirouac KN; Ling H
    Proc Natl Acad Sci U S A; 2011 Feb; 108(8):3210-5. PubMed ID: 21300901
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Structure of DNA polymerase beta with the mutagenic DNA lesion 8-oxodeoxyguanine reveals structural insights into its coding potential.
    Krahn JM; Beard WA; Miller H; Grollman AP; Wilson SH
    Structure; 2003 Jan; 11(1):121-7. PubMed ID: 12517346
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Toward understanding the mutagenicity of an environmental carcinogen: structural insights into nucleotide incorporation preferences.
    Perlow RA; Broyde S
    J Mol Biol; 2002 Sep; 322(2):291-309. PubMed ID: 12217692
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Role of hoogsteen edge hydrogen bonding at template purines in nucleotide incorporation by human DNA polymerase iota.
    Johnson RE; Haracska L; Prakash L; Prakash S
    Mol Cell Biol; 2006 Sep; 26(17):6435-41. PubMed ID: 16914729
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Structural basis for the inefficient nucleotide incorporation opposite cisplatin-DNA lesion by human DNA polymerase β.
    Koag MC; Lai L; Lee S
    J Biol Chem; 2014 Nov; 289(45):31341-8. PubMed ID: 25237188
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Structural insights into the bypass of the major deaminated purines by translesion synthesis DNA polymerase.
    Jung H; Hawkins M; Lee S
    Biochem J; 2020 Dec; 477(24):4797-4810. PubMed ID: 33258913
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Mutagenic conformation of 8-oxo-7,8-dihydro-2'-dGTP in the confines of a DNA polymerase active site.
    Batra VK; Beard WA; Hou EW; Pedersen LC; Prasad R; Wilson SH
    Nat Struct Mol Biol; 2010 Jul; 17(7):889-90. PubMed ID: 20526335
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.