BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

231 related articles for article (PubMed ID: 31572371)

  • 1. Lovastatin Inhibits HIV-1-Induced MHC-I Downregulation by Targeting Nef-AP-1 Complex Formation: A New Strategy to Boost Immune Eradication of HIV-1 Infected Cells.
    Liu B; Zhang X; Zhang W; Wu L; Jing S; Liu W; Xia B; Zou F; Lu L; Ma X; He D; Hu Q; Zhang Y; Deng K; Cai W; Tang X; Peng T; Zhang H; Li L
    Front Immunol; 2019; 10():2151. PubMed ID: 31572371
    [TBL] [Abstract][Full Text] [Related]  

  • 2. An Amino Acid Polymorphism within the HIV-1 Nef Dileucine Motif Functionally Uncouples Cell Surface CD4 and SERINC5 Downregulation.
    Mumby MJ; Johnson AL; Trothen SM; Edgar CR; Gibson R; Stathopulos PB; Arts EJ; Dikeakos JD
    J Virol; 2021 Jul; 95(16):e0058821. PubMed ID: 34037423
    [TBL] [Abstract][Full Text] [Related]  

  • 3. HIV-1 Nef Antagonizes SERINC5 Restriction by Downregulation of SERINC5 via the Endosome/Lysosome System.
    Shi J; Xiong R; Zhou T; Su P; Zhang X; Qiu X; Li H; Li S; Yu C; Wang B; Ding C; Smithgall TE; Zheng YH
    J Virol; 2018 Jun; 92(11):. PubMed ID: 29514909
    [TBL] [Abstract][Full Text] [Related]  

  • 4. HIV Subtype and Nef-Mediated Immune Evasion Function Correlate with Viral Reservoir Size in Early-Treated Individuals.
    Omondi FH; Chandrarathna S; Mujib S; Brumme CJ; Jin SW; Sudderuddin H; Miller RL; Rahimi A; Laeyendecker O; Bonner P; Yue FY; Benko E; Kovacs CM; Brockman MA; Ostrowski M; Brumme ZL
    J Virol; 2019 Mar; 93(6):. PubMed ID: 30602611
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The Antagonism of HIV-1 Nef to SERINC5 Particle Infectivity Restriction Involves the Counteraction of Virion-Associated Pools of the Restriction Factor.
    Trautz B; Pierini V; Wombacher R; Stolp B; Chase AJ; Pizzato M; Fackler OT
    J Virol; 2016 Dec; 90(23):10915-10927. PubMed ID: 27681140
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Resistance of Major Histocompatibility Complex Class B (MHC-B) to Nef-Mediated Downregulation Relative to that of MHC-A Is Conserved among Primate Lentiviruses and Influences Antiviral T Cell Responses in HIV-1-Infected Individuals.
    Mwimanzi F; Toyoda M; Mahiti M; Mann JK; Martin JN; Bangsberg D; Brockman MA; Goulder P; Kirchhoff F; Brumme ZL; Ndung'u T; Ueno T
    J Virol; 2018 Jan; 92(1):. PubMed ID: 29046444
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Simian and human immunodeficiency virus Nef proteins use different surfaces to downregulate class I major histocompatibility complex antigen expression.
    Swigut T; Iafrate AJ; Muench J; Kirchhoff F; Skowronski J
    J Virol; 2000 Jun; 74(12):5691-701. PubMed ID: 10823877
    [TBL] [Abstract][Full Text] [Related]  

  • 8. AP-2 Adaptor Complex-Dependent Enhancement of HIV-1 Replication by Nef in the Absence of the Nef/AP-2 Targets SERINC5 and CD4.
    Olety B; Usami Y; Wu Y; Peters P; Göttlinger H
    mBio; 2023 Feb; 14(1):e0338222. PubMed ID: 36622146
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Two Functional Variants of AP-1 Complexes Composed of either γ2 or γ1 Subunits Are Independently Required for Major Histocompatibility Complex Class I Downregulation by HIV-1 Nef.
    Tavares LA; de Carvalho JV; Costa CS; Silveira RM; de Carvalho AN; Donadi EA; daSilva LLP
    J Virol; 2020 Mar; 94(7):. PubMed ID: 31915283
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Tight-Binding Hydroxypyrazole HIV-1 Nef Inhibitors Suppress Viral Replication in Donor Mononuclear Cells and Reverse Nef-Mediated MHC-I Downregulation.
    Shi H; Tice CM; Emert-Sedlak L; Chen L; Li WF; Carlsen M; Wrobel JE; Reitz AB; Smithgall TE
    ACS Infect Dis; 2020 Feb; 6(2):302-312. PubMed ID: 31775511
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Concanamycin A counteracts HIV-1 Nef to enhance immune clearance of infected primary cells by cytotoxic T lymphocytes.
    Painter MM; Zimmerman GE; Merlino MS; Robertson AW; Terry VH; Ren X; McLeod MR; Gomez-Rodriguez L; Garcia KA; Leonard JA; Leopold KE; Neevel AJ; Lubow J; Olson E; Piechocka-Trocha A; Collins DR; Tripathi A; Raghavan M; Walker BD; Hurley JH; Sherman DH; Collins KL
    Proc Natl Acad Sci U S A; 2020 Sep; 117(38):23835-23846. PubMed ID: 32900948
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Maintenance of AP-2-Dependent Functional Activities of Nef Restricts Pathways of Immune Escape from CD8 T Lymphocyte Responses.
    Schouest B; Weiler AM; Janaka SK; Myers TA; Das A; Wilder SC; Furlott J; Baddoo M; Flemington EK; Rakasz EG; Evans DT; Friedrich TC; Maness NJ
    J Virol; 2018 Mar; 92(5):. PubMed ID: 29237831
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Human immunodeficiency virus type 1 Nef-mediated downregulation of CD4 correlates with Nef enhancement of viral pathogenesis.
    Stoddart CA; Geleziunas R; Ferrell S; Linquist-Stepps V; Moreno ME; Bare C; Xu W; Yonemoto W; Bresnahan PA; McCune JM; Greene WC
    J Virol; 2003 Feb; 77(3):2124-33. PubMed ID: 12525647
    [TBL] [Abstract][Full Text] [Related]  

  • 14. CD4 and major histocompatibility complex class I downregulation by the human immunodeficiency virus type 1 nef protein in pediatric AIDS progression.
    Casartelli N; Di Matteo G; Potestà M; Rossi P; Doria M
    J Virol; 2003 Nov; 77(21):11536-45. PubMed ID: 14557639
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Downregulation of major histocompatibility class I on human dendritic cells by HIV Nef impairs antigen presentation to HIV-specific CD8+ T lymphocytes.
    Andrieu M; Chassin D; Desoutter JF; Bouchaert I; Baillet M; Hanau D; Guillet JG; Hosmalin A
    AIDS Res Hum Retroviruses; 2001 Sep; 17(14):1365-70. PubMed ID: 11602047
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Natural HIV-1 Nef Polymorphisms Impair SERINC5 Downregulation Activity.
    Jin SW; Alsahafi N; Kuang XT; Swann SA; Toyoda M; Göttlinger H; Walker BD; Ueno T; Finzi A; Brumme ZL; Brockman MA
    Cell Rep; 2019 Nov; 29(6):1449-1457.e5. PubMed ID: 31693887
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Differential Ability of Primary HIV-1 Nef Isolates To Downregulate HIV-1 Entry Receptors.
    Toyoda M; Ogata Y; Mahiti M; Maeda Y; Kuang XT; Miura T; Jessen H; Walker BD; Brockman MA; Brumme ZL; Ueno T
    J Virol; 2015 Sep; 89(18):9639-52. PubMed ID: 26178998
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Nef homodimers down-regulate SERINC5 by AP-2-mediated endocytosis to promote HIV-1 infectivity.
    Staudt RP; Smithgall TE
    J Biol Chem; 2020 Nov; 295(46):15540-15552. PubMed ID: 32873704
    [TBL] [Abstract][Full Text] [Related]  

  • 19. A Conserved Acidic Residue in the C-Terminal Flexible Loop of HIV-1 Nef Contributes to the Activity of SERINC5 and CD4 Downregulation.
    Firrito C; Bertelli C; Rosa A; Chande A; Ananth S; van Dijk H; Fackler OT; Stoneham C; Singh R; Guatelli J; Pizzato M
    Viruses; 2023 Feb; 15(3):. PubMed ID: 36992361
    [TBL] [Abstract][Full Text] [Related]  

  • 20. HIV-1 Nef sequence and functional compartmentalization in the gut is not due to differential cytotoxic T lymphocyte selective pressure.
    Lewis MJ; Frohnen P; Ibarrondo FJ; Reed D; Iyer V; Ng HL; Elliott J; Yang OO; Anton P
    PLoS One; 2013; 8(9):e75620. PubMed ID: 24058696
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.