BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

212 related articles for article (PubMed ID: 31573509)

  • 1. Interplay of disordered and ordered regions of a human small heat shock protein yields an ensemble of 'quasi-ordered' states.
    Clouser AF; Baughman HE; Basanta B; Guttman M; Nath A; Klevit RE
    Elife; 2019 Oct; 8():. PubMed ID: 31573509
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Release of a disordered domain enhances HspB1 chaperone activity toward tau.
    Baughman HER; Pham TT; Adams CS; Nath A; Klevit RE
    Proc Natl Acad Sci U S A; 2020 Feb; 117(6):2923-2929. PubMed ID: 31974309
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Chaperone-like activity of the N-terminal region of a human small heat shock protein and chaperone-functionalized nanoparticles.
    Gliniewicz EF; Chambers KM; De Leon ER; Sibai D; Campbell HC; McMenimen KA
    Proteins; 2019 May; 87(5):401-415. PubMed ID: 30684363
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Specific sequences in the N-terminal domain of human small heat-shock protein HSPB6 dictate preferential hetero-oligomerization with the orthologue HSPB1.
    Heirbaut M; Lermyte F; Martin EM; Beelen S; Sobott F; Strelkov SV; Weeks SD
    J Biol Chem; 2017 Jun; 292(24):9944-9957. PubMed ID: 28487364
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Chaperone activity of human small heat shock protein-GST fusion proteins.
    Arbach H; Butler C; McMenimen KA
    Cell Stress Chaperones; 2017 Jul; 22(4):503-515. PubMed ID: 28130664
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Peeking from behind the veil of enigma: emerging insights on small heat shock protein structure and function.
    Klevit RE
    Cell Stress Chaperones; 2020 Jul; 25(4):573-580. PubMed ID: 32270443
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Substrate binding site flexibility of the small heat shock protein molecular chaperones.
    Jaya N; Garcia V; Vierling E
    Proc Natl Acad Sci U S A; 2009 Sep; 106(37):15604-9. PubMed ID: 19717454
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Engineering of a Polydisperse Small Heat-Shock Protein Reveals Conserved Motifs of Oligomer Plasticity.
    Mishra S; Chandler SA; Williams D; Claxton DP; Koteiche HA; Stewart PL; Benesch JLP; Mchaourab HS
    Structure; 2018 Aug; 26(8):1116-1126.e4. PubMed ID: 29983375
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The Role of the Arginine in the Conserved N-Terminal Domain RLFDQxFG Motif of Human Small Heat Shock Proteins HspB1, HspB4, HspB5, HspB6, and HspB8.
    Shatov VM; Weeks SD; Strelkov SV; Gusev NB
    Int J Mol Sci; 2018 Jul; 19(7):. PubMed ID: 30036999
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Terminal Regions Confer Plasticity to the Tetrameric Assembly of Human HspB2 and HspB3.
    Clark AR; Vree Egberts W; Kondrat FDL; Hilton GR; Ray NJ; Cole AR; Carver JA; Benesch JLP; Keep NH; Boelens WC; Slingsby C
    J Mol Biol; 2018 Sep; 430(18 Pt B):3297-3310. PubMed ID: 29969581
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Three-dimensional structure of α-crystallin domain dimers of human small heat shock proteins HSPB1 and HSPB6.
    Baranova EV; Weeks SD; Beelen S; Bukach OV; Gusev NB; Strelkov SV
    J Mol Biol; 2011 Aug; 411(1):110-22. PubMed ID: 21641913
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Disordered region encodes α-crystallin chaperone activity toward lens client γD-crystallin.
    Woods CN; Ulmer LD; Guttman M; Bush MF; Klevit RE
    Proc Natl Acad Sci U S A; 2023 Feb; 120(6):e2213765120. PubMed ID: 36719917
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The Diverse Functions of Small Heat Shock Proteins in the Proteostasis Network.
    Reinle K; Mogk A; Bukau B
    J Mol Biol; 2022 Jan; 434(1):167157. PubMed ID: 34271010
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The functional roles of the unstructured N- and C-terminal regions in αB-crystallin and other mammalian small heat-shock proteins.
    Carver JA; Grosas AB; Ecroyd H; Quinlan RA
    Cell Stress Chaperones; 2017 Jul; 22(4):627-638. PubMed ID: 28391594
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Human HspB1, HspB3, HspB5 and HspB8: Shaping these disease factors during vertebrate evolution.
    Benndorf R; Velazquez R; Zehr JD; Pond SLK; Martin JL; Lucaci AG
    Cell Stress Chaperones; 2022 Jul; 27(4):309-323. PubMed ID: 35678958
    [TBL] [Abstract][Full Text] [Related]  

  • 16. A Mechanism of Subunit Recruitment in Human Small Heat Shock Protein Oligomers.
    Delbecq SP; Rosenbaum JC; Klevit RE
    Biochemistry; 2015 Jul; 54(28):4276-84. PubMed ID: 26098708
    [TBL] [Abstract][Full Text] [Related]  

  • 17. NMR spectroscopy of alpha-crystallin. Insights into the structure, interactions and chaperone action of small heat-shock proteins.
    Carver JA; Lindner RA
    Int J Biol Macromol; 1998; 22(3-4):197-209. PubMed ID: 9650074
    [TBL] [Abstract][Full Text] [Related]  

  • 18. An unusual dimeric small heat shock protein provides insight into the mechanism of this class of chaperones.
    Basha E; Jones C; Blackwell AE; Cheng G; Waters ER; Samsel KA; Siddique M; Pett V; Wysocki V; Vierling E
    J Mol Biol; 2013 May; 425(10):1683-96. PubMed ID: 23416558
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Crystal structures of Xanthomonas small heat shock protein provide a structural basis for an active molecular chaperone oligomer.
    Hilario E; Martin FJ; Bertolini MC; Fan L
    J Mol Biol; 2011 Apr; 408(1):74-86. PubMed ID: 21315085
    [TBL] [Abstract][Full Text] [Related]  

  • 20. HspB1 and Hsc70 chaperones engage distinct tau species and have different inhibitory effects on amyloid formation.
    Baughman HER; Clouser AF; Klevit RE; Nath A
    J Biol Chem; 2018 Feb; 293(8):2687-2700. PubMed ID: 29298892
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.