BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

259 related articles for article (PubMed ID: 31577957)

  • 1. Liver-Type Glutaminase GLS2 Is a Druggable Metabolic Node in Luminal-Subtype Breast Cancer.
    Lukey MJ; Cluntun AA; Katt WP; Lin MJ; Druso JE; Ramachandran S; Erickson JW; Le HH; Wang ZE; Blank B; Greene KS; Cerione RA
    Cell Rep; 2019 Oct; 29(1):76-88.e7. PubMed ID: 31577957
    [TBL] [Abstract][Full Text] [Related]  

  • 2. GLS2 is protumorigenic in breast cancers.
    Dias MM; Adamoski D; Dos Reis LM; Ascenção CFR; de Oliveira KRS; Mafra ACP; da Silva Bastos AC; Quintero M; de G Cassago C; Ferreira IM; Fidelis CHV; Rocco SA; Bajgelman MC; Stine Z; Berindan-Neagoe I; Calin GA; Ambrosio ALB; Dias SMG
    Oncogene; 2020 Jan; 39(3):690-702. PubMed ID: 31541193
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Structure and activation mechanism of the human liver-type glutaminase GLS2.
    Ferreira IM; Quesñay JEN; Bastos AC; Rodrigues CT; Vollmar M; Krojer T; Strain-Damerell C; Burgess-Brown NA; von Delft F; Yue WW; Dias SM; Ambrosio AL
    Biochimie; 2021 Jun; 185():96-104. PubMed ID: 33746066
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Glutamine to proline conversion is associated with response to glutaminase inhibition in breast cancer.
    Grinde MT; Hilmarsdottir B; Tunset HM; Henriksen IM; Kim J; Haugen MH; Rye MB; Mælandsmo GM; Moestue SA
    Breast Cancer Res; 2019 May; 21(1):61. PubMed ID: 31088535
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Discovery of selective inhibitors of Glutaminase-2, which inhibit mTORC1, activate autophagy and inhibit proliferation in cancer cells.
    Lee YZ; Yang CW; Chang HY; Hsu HY; Chen IS; Chang HS; Lee CH; Lee JC; Kumar CR; Qiu YQ; Chao YS; Lee SJ
    Oncotarget; 2014 Aug; 5(15):6087-101. PubMed ID: 25026281
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Epigenetic silencing of glutaminase 2 in human liver and colon cancers.
    Zhang J; Wang C; Chen M; Cao J; Zhong Y; Chen L; Shen HM; Xia D
    BMC Cancer; 2013 Dec; 13():601. PubMed ID: 24330717
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Phosphate-activated glutaminase (GLS2), a p53-inducible regulator of glutamine metabolism and reactive oxygen species.
    Suzuki S; Tanaka T; Poyurovsky MV; Nagano H; Mayama T; Ohkubo S; Lokshin M; Hosokawa H; Nakayama T; Suzuki Y; Sugano S; Sato E; Nagao T; Yokote K; Tatsuno I; Prives C
    Proc Natl Acad Sci U S A; 2010 Apr; 107(16):7461-6. PubMed ID: 20351271
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Transcription factor GATA3 expression is induced by GLS2 overexpression in a glioblastoma cell line but is GLS2-independent in patient-derived glioblastoma.
    Majewska E; Rola R; Barczewska M; Marquez J; Albrecht J; Szeliga M
    J Physiol Pharmacol; 2017 Apr; 68(2):209-214. PubMed ID: 28614770
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The role of glutaminase in cancer.
    Masisi BK; El Ansari R; Alfarsi L; Rakha EA; Green AR; Craze ML
    Histopathology; 2020 Mar; 76(4):498-508. PubMed ID: 31596504
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Glutamine synthetase is a genetic determinant of cell type-specific glutamine independence in breast epithelia.
    Kung HN; Marks JR; Chi JT
    PLoS Genet; 2011 Aug; 7(8):e1002229. PubMed ID: 21852960
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The oncogenic transcription factor c-Jun regulates glutaminase expression and sensitizes cells to glutaminase-targeted therapy.
    Lukey MJ; Greene KS; Erickson JW; Wilson KF; Cerione RA
    Nat Commun; 2016 Apr; 7():11321. PubMed ID: 27089238
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Two Faces of Glutaminase GLS2 in Carcinogenesis.
    Buczkowska J; Szeliga M
    Cancers (Basel); 2023 Nov; 15(23):. PubMed ID: 38067269
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Glutaminase 2 is a novel negative regulator of small GTPase Rac1 and mediates p53 function in suppressing metastasis.
    Zhang C; Liu J; Zhao Y; Yue X; Zhu Y; Wang X; Wu H; Blanco F; Li S; Bhanot G; Haffty BG; Hu W; Feng Z
    Elife; 2016 Jan; 5():e10727. PubMed ID: 26751560
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Glutaminase is essential for the growth of triple-negative breast cancer cells with a deregulated glutamine metabolism pathway and its suppression synergizes with mTOR inhibition.
    Lampa M; Arlt H; He T; Ospina B; Reeves J; Zhang B; Murtie J; Deng G; Barberis C; Hoffmann D; Cheng H; Pollard J; Winter C; Richon V; Garcia-Escheverria C; Adrian F; Wiederschain D; Srinivasan L
    PLoS One; 2017; 12(9):e0185092. PubMed ID: 28950000
    [TBL] [Abstract][Full Text] [Related]  

  • 15. A tale of two glutaminases: homologous enzymes with distinct roles in tumorigenesis.
    Katt WP; Lukey MJ; Cerione RA
    Future Med Chem; 2017 Jan; 9(2):223-243. PubMed ID: 28111979
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Glutaminase isoenzymes in the metabolic therapy of cancer.
    Matés JM; Campos-Sandoval JA; Márquez J
    Biochim Biophys Acta Rev Cancer; 2018 Dec; 1870(2):158-164. PubMed ID: 30053497
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Nuclear Translocation of Glutaminase GLS2 in Human Cancer Cells Associates with Proliferation Arrest and Differentiation.
    López de la Oliva AR; Campos-Sandoval JA; Gómez-García MC; Cardona C; Martín-Rufián M; Sialana FJ; Castilla L; Bae N; Lobo C; Peñalver A; García-Frutos M; Carro D; Enrique V; Paz JC; Mirmira RG; Gutiérrez A; Alonso FJ; Segura JA; Matés JM; Lubec G; Márquez J
    Sci Rep; 2020 Feb; 10(1):2259. PubMed ID: 32042057
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Metabolic Reprogramming of Cancer by Chemicals that Target Glutaminase Isoenzymes.
    Matés JM; Campos-Sandoval JA; de Los Santos-Jiménez J; Segura JA; Alonso FJ; Márquez J
    Curr Med Chem; 2020; 27(32):5317-5339. PubMed ID: 31038055
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Myc promotes glutaminolysis in human neuroblastoma through direct activation of glutaminase 2.
    Xiao D; Ren P; Su H; Yue M; Xiu R; Hu Y; Liu H; Qing G
    Oncotarget; 2015 Dec; 6(38):40655-66. PubMed ID: 26528759
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Knock-down of glutaminase 2 expression decreases glutathione, NADH, and sensitizes cervical cancer to ionizing radiation.
    Xiang L; Xie G; Liu C; Zhou J; Chen J; Yu S; Li J; Pang X; Shi H; Liang H
    Biochim Biophys Acta; 2013 Dec; 1833(12):2996-3005. PubMed ID: 23954443
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.