232 related articles for article (PubMed ID: 31581002)
1. Development of chalcone-O-alkylamine derivatives as multifunctional agents against Alzheimer's disease.
Bai P; Wang K; Zhang P; Shi J; Cheng X; Zhang Q; Zheng C; Cheng Y; Yang J; Lu X; Sang Z
Eur J Med Chem; 2019 Dec; 183():111737. PubMed ID: 31581002
[TBL] [Abstract][Full Text] [Related]
2. Design, synthesis and evaluation of novel ferulic acid-O-alkylamine derivatives as potential multifunctional agents for the treatment of Alzheimer's disease.
Sang Z; Pan W; Wang K; Ma Q; Yu L; Yang Y; Bai P; Leng C; Xu Q; Li X; Tan Z; Liu W
Eur J Med Chem; 2017 Apr; 130():379-392. PubMed ID: 28279845
[TBL] [Abstract][Full Text] [Related]
3. Design, synthesis and biological evaluation of 4'-aminochalcone-rivastigmine hybrids as multifunctional agents for the treatment of Alzheimer's disease.
Xiao G; Li Y; Qiang X; Xu R; Zheng Y; Cao Z; Luo L; Yang X; Sang Z; Su F; Deng Y
Bioorg Med Chem; 2017 Feb; 25(3):1030-1041. PubMed ID: 28011206
[TBL] [Abstract][Full Text] [Related]
4. Discovery of novel propargylamine-modified 4-aminoalkyl imidazole substituted pyrimidinylthiourea derivatives as multifunctional agents for the treatment of Alzheimer's disease.
Xu YX; Wang H; Li XK; Dong SN; Liu WW; Gong Q; Wang TD; Tang Y; Zhu J; Li J; Zhang HY; Mao F
Eur J Med Chem; 2018 Jan; 143():33-47. PubMed ID: 29172081
[TBL] [Abstract][Full Text] [Related]
5. Multifunctional 5,6-dimethoxybenzo[d]isothiazol-3(2H)-one-N-alkylbenzylamine derivatives with acetylcholinesterase, monoamine oxidases and β-amyloid aggregation inhibitory activities as potential agents against Alzheimer's disease.
Xu R; Xiao G; Li Y; Liu H; Song Q; Zhang X; Yang Z; Zheng Y; Tan Z; Deng Y
Bioorg Med Chem; 2018 May; 26(8):1885-1895. PubMed ID: 29500132
[TBL] [Abstract][Full Text] [Related]
6. Design, synthesis and evaluation of 4'-OH-flurbiprofen-chalcone hybrids as potential multifunctional agents for Alzheimer's disease treatment.
Cao Z; Yang J; Xu R; Song Q; Zhang X; Liu H; Qiang X; Li Y; Tan Z; Deng Y
Bioorg Med Chem; 2018 Mar; 26(5):1102-1115. PubMed ID: 29409707
[TBL] [Abstract][Full Text] [Related]
7. Design, synthesis and biological evaluation of 3,4-dihydro-2(1H)-quinoline-O-alkylamine derivatives as new multipotent cholinesterase/monoamine oxidase inhibitors for the treatment of Alzheimer's disease.
Sang Z; Pan W; Wang K; Ma Q; Yu L; Liu W
Bioorg Med Chem; 2017 Jun; 25(12):3006-3017. PubMed ID: 28487125
[TBL] [Abstract][Full Text] [Related]
8. Rational Design and Multibiological Profiling of Novel Donepezil-Trolox Hybrids against Alzheimer's Disease, with Cholinergic, Antioxidant, Neuroprotective, and Cognition Enhancing Properties.
Cai P; Fang SQ; Yang XL; Wu JJ; Liu QH; Hong H; Wang XB; Kong LY
ACS Chem Neurosci; 2017 Nov; 8(11):2496-2511. PubMed ID: 28806057
[TBL] [Abstract][Full Text] [Related]
9. Multifunctional scutellarin-rivastigmine hybrids with cholinergic, antioxidant, biometal chelating and neuroprotective properties for the treatment of Alzheimer's disease.
Sang Z; Li Y; Qiang X; Xiao G; Liu Q; Tan Z; Deng Y
Bioorg Med Chem; 2015 Feb; 23(4):668-80. PubMed ID: 25614117
[TBL] [Abstract][Full Text] [Related]
10. Design, synthesis and evaluation of novel tacrine-(β-carboline) hybrids as multifunctional agents for the treatment of Alzheimer's disease.
Lan JS; Xie SS; Li SY; Pan LF; Wang XB; Kong LY
Bioorg Med Chem; 2014 Nov; 22(21):6089-104. PubMed ID: 25282654
[TBL] [Abstract][Full Text] [Related]
11. Multifunctional novel Diallyl disulfide (DADS) derivatives with β-amyloid-reducing, cholinergic, antioxidant and metal chelating properties for the treatment of Alzheimer's disease.
Manral A; Saini V; Meena P; Tiwari M
Bioorg Med Chem; 2015 Oct; 23(19):6389-403. PubMed ID: 26337018
[TBL] [Abstract][Full Text] [Related]
12. Design, synthesis, and biological evaluation of scutellarein carbamate derivatives as potential multifunctional agents for the treatment of Alzheimer's disease.
Sang ZP; Qiang XM; Li Y; Wu B; Zhang H; Zhao MG; Deng Y
Chem Biol Drug Des; 2015 Nov; 86(5):1168-77. PubMed ID: 25941042
[TBL] [Abstract][Full Text] [Related]
13. Pyridoxine-resveratrol hybrids Mannich base derivatives as novel dual inhibitors of AChE and MAO-B with antioxidant and metal-chelating properties for the treatment of Alzheimer's disease.
Yang X; Qiang X; Li Y; Luo L; Xu R; Zheng Y; Cao Z; Tan Z; Deng Y
Bioorg Chem; 2017 Apr; 71():305-314. PubMed ID: 28267984
[TBL] [Abstract][Full Text] [Related]
14. Design, synthesis and evaluation of scutellarein-O-alkylamines as multifunctional agents for the treatment of Alzheimer's disease.
Sang Z; Qiang X; Li Y; Yuan W; Liu Q; Shi Y; Ang W; Luo Y; Tan Z; Deng Y
Eur J Med Chem; 2015 Apr; 94():348-66. PubMed ID: 25778991
[TBL] [Abstract][Full Text] [Related]
15. Design, synthesis and biological evaluation of 2-acetyl-5-O-(amino-alkyl)phenol derivatives as multifunctional agents for the treatment of Alzheimer's disease.
Sang Z; Wang K; Wang H; Wang H; Ma Q; Han X; Ye M; Yu L; Liu W
Bioorg Med Chem Lett; 2017 Nov; 27(22):5046-5052. PubMed ID: 29033233
[TBL] [Abstract][Full Text] [Related]
16. Multifunctional thioxanthone derivatives with acetylcholinesterase, monoamine oxidases and β-amyloid aggregation inhibitory activities as potential agents against Alzheimer's disease.
Luo L; Li Y; Qiang X; Cao Z; Xu R; Yang X; Xiao G; Song Q; Tan Z; Deng Y
Bioorg Med Chem; 2017 Mar; 25(6):1997-2009. PubMed ID: 28237559
[TBL] [Abstract][Full Text] [Related]
17. Multitarget drug design strategy against Alzheimer's disease: Homoisoflavonoid Mannich base derivatives serve as acetylcholinesterase and monoamine oxidase B dual inhibitors with multifunctional properties.
Li Y; Qiang X; Luo L; Yang X; Xiao G; Zheng Y; Cao Z; Sang Z; Su F; Deng Y
Bioorg Med Chem; 2017 Jan; 25(2):714-726. PubMed ID: 27923535
[TBL] [Abstract][Full Text] [Related]
18. Multifunctional coumarin derivatives: monoamine oxidase B (MAO-B) inhibition, anti-β-amyloid (Aβ) aggregation and metal chelation properties against Alzheimer's disease.
Huang M; Xie SS; Jiang N; Lan JS; Kong LY; Wang XB
Bioorg Med Chem Lett; 2015 Feb; 25(3):508-13. PubMed ID: 25542589
[TBL] [Abstract][Full Text] [Related]
19. Design, synthesis and biological activity of novel donepezil derivatives bearing N-benzyl pyridinium moiety as potent and dual binding site acetylcholinesterase inhibitors.
Lan JS; Zhang T; Liu Y; Yang J; Xie SS; Liu J; Miao ZY; Ding Y
Eur J Med Chem; 2017 Jun; 133():184-196. PubMed ID: 28388521
[TBL] [Abstract][Full Text] [Related]
20. Synthesis and pharmacological evaluation of donepezil-based agents as new cholinesterase/monoamine oxidase inhibitors for the potential application against Alzheimer's disease.
Li F; Wang ZM; Wu JJ; Wang J; Xie SS; Lan JS; Xu W; Kong LY; Wang XB
J Enzyme Inhib Med Chem; 2016; 31(sup3):41-53. PubMed ID: 27384289
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
