BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

307 related articles for article (PubMed ID: 31586207)

  • 1. Tissue-specific autoimmunity controlled by Aire in thymic and peripheral tolerance mechanisms.
    Matsumoto M; Tsuneyama K; Morimoto J; Hosomichi K; Matsumoto M; Nishijima H
    Int Immunol; 2020 Feb; 32(2):117-131. PubMed ID: 31586207
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Paradoxical development of polymyositis-like autoimmunity through augmented expression of autoimmune regulator (AIRE).
    Nishijima H; Kajimoto T; Matsuoka Y; Mouri Y; Morimoto J; Matsumoto M; Kawano H; Nishioka Y; Uehara H; Izumi K; Tsuneyama K; Okazaki IM; Okazaki T; Hosomichi K; Shiraki A; Shibutani M; Mitsumori K; Matsumoto M
    J Autoimmun; 2018 Jan; 86():75-92. PubMed ID: 28931462
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Thymic development of autoreactive T cells in NOD mice is regulated in an age-dependent manner.
    He Q; Morillon YM; Spidale NA; Kroger CJ; Liu B; Sartor RB; Wang B; Tisch R
    J Immunol; 2013 Dec; 191(12):5858-66. PubMed ID: 24198282
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Breakdown in peripheral tolerance in type 1 diabetes in mice and humans.
    Jeker LT; Bour-Jordan H; Bluestone JA
    Cold Spring Harb Perspect Med; 2012 Mar; 2(3):a007807. PubMed ID: 22393537
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Complete diabetes protection despite delayed thymic tolerance in NOD8.3 TCR transgenic mice due to antigen-induced extrathymic deletion of T cells.
    Krishnamurthy B; Chee J; Jhala G; Fynch S; Graham KL; Santamaria P; Morahan G; Allison J; Izon D; Thomas HE; Kay TW
    Diabetes; 2012 Feb; 61(2):425-35. PubMed ID: 22190647
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Medullary thymic epithelial cells and CD8α
    Herbin O; Bonito AJ; Jeong S; Weinstein EG; Rahman AH; Xiong H; Merad M; Alexandropoulos K
    J Autoimmun; 2016 Dec; 75():141-149. PubMed ID: 27543048
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Age-related deregulation of Aire and peripheral tissue antigen genes in the thymic stroma of non-obese diabetic (NOD) mice is associated with autoimmune type 1 diabetes mellitus (DM-1).
    Fornari TA; Donate PB; Macedo C; Marques MM; Magalhães DA; Passos GA
    Mol Cell Biochem; 2010 Sep; 342(1-2):21-8. PubMed ID: 20414703
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Essential roles of insulin expression in Aire+ tolerogenic dendritic cells in maintaining peripheral self-tolerance of islet β-cells.
    Grupillo M; Gualtierotti G; He J; Sisino G; Bottino R; Rudert WA; Trucco M; Fan Y
    Cell Immunol; 2012; 273(2):115-23. PubMed ID: 22297234
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Thymic B Cell-Mediated Attack of Thymic Stroma Precedes Type 1 Diabetes Development.
    Pinto AI; Smith J; Kissack MR; Hogg KG; Green EA
    Front Immunol; 2018; 9():1281. PubMed ID: 29930554
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Mode of Tolerance Induction and Requirement for Aire Are Governed by the Cell Types That Express Self-Antigen and Those That Present Antigen.
    Mouri Y; Ueda Y; Yamano T; Matsumoto M; Tsuneyama K; Kinashi T; Matsumoto M
    J Immunol; 2017 Dec; 199(12):3959-3971. PubMed ID: 29101311
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Control of central and peripheral tolerance by Aire.
    Metzger TC; Anderson MS
    Immunol Rev; 2011 May; 241(1):89-103. PubMed ID: 21488892
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Development of autoimmunity against transcriptionally unrepressed target antigen in the thymus of Aire-deficient mice.
    Kuroda N; Mitani T; Takeda N; Ishimaru N; Arakaki R; Hayashi Y; Bando Y; Izumi K; Takahashi T; Nomura T; Sakaguchi S; Ueno T; Takahama Y; Uchida D; Sun S; Kajiura F; Mouri Y; Han H; Matsushima A; Yamada G; Matsumoto M
    J Immunol; 2005 Feb; 174(4):1862-70. PubMed ID: 15699112
    [TBL] [Abstract][Full Text] [Related]  

  • 13. MHC-mismatched mixed chimerism restores peripheral tolerance of noncross-reactive autoreactive T cells in NOD mice.
    Zhang M; Racine JJ; Lin Q; Liu Y; Tang S; Qin Q; Qi T; Riggs AD; Zeng D
    Proc Natl Acad Sci U S A; 2018 Mar; 115(10):E2329-E2337. PubMed ID: 29463744
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Neonatal tolerance revisited: a perinatal window for Aire control of autoimmunity.
    Guerau-de-Arellano M; Martinic M; Benoist C; Mathis D
    J Exp Med; 2009 Jun; 206(6):1245-52. PubMed ID: 19487417
    [TBL] [Abstract][Full Text] [Related]  

  • 15. T-cell receptor-transgenic NOD mice: a reductionist approach to understand autoimmune diabetes.
    Yang Y; Santamaria P
    J Autoimmun; 2004 Mar; 22(2):121-9. PubMed ID: 14987740
    [No Abstract]   [Full Text] [Related]  

  • 16. Genetic basis of altered central tolerance and autoimmune diseases: a lesson from AIRE mutations.
    Capalbo D; Giardino G; Martino LD; Palamaro L; Romano R; Gallo V; Cirillo E; Salerno M; Pignata C
    Int Rev Immunol; 2012 Oct; 31(5):344-62. PubMed ID: 23083345
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Alteration of intra-pancreatic target-organ specificity by abrogation of Aire in NOD mice.
    Niki S; Oshikawa K; Mouri Y; Hirota F; Matsushima A; Yano M; Han H; Bando Y; Izumi K; Matsumoto M; Nakayama KI; Kuroda N; Matsumoto M
    J Clin Invest; 2006 May; 116(5):1292-301. PubMed ID: 16628255
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Images of self: a model for tonic peripheral tolerance.
    Rudy G; Lew AM
    Immunol Cell Biol; 1993 Aug; 71 ( Pt 4)():327-36. PubMed ID: 7901151
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Ectopic Aire Expression in the Thymic Cortex Reveals Inherent Properties of Aire as a Tolerogenic Factor within the Medulla.
    Nishijima H; Kitano S; Miyachi H; Morimoto J; Kawano H; Hirota F; Morita R; Mouri Y; Masuda K; Imoto I; Ikuta K; Matsumoto M
    J Immunol; 2015 Nov; 195(10):4641-9. PubMed ID: 26453754
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Recent insights into the role and molecular mechanisms of the autoimmune regulator (AIRE) gene in autoimmunity.
    Fierabracci A
    Autoimmun Rev; 2011 Jan; 10(3):137-43. PubMed ID: 20850570
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 16.