381 related articles for article (PubMed ID: 31588569)
1. AcrB: a mean, keen, drug efflux machine.
Kobylka J; Kuth MS; Müller RT; Geertsma ER; Pos KM
Ann N Y Acad Sci; 2020 Jan; 1459(1):38-68. PubMed ID: 31588569
[TBL] [Abstract][Full Text] [Related]
2. Molecular basis for inhibition of AcrB multidrug efflux pump by novel and powerful pyranopyridine derivatives.
Sjuts H; Vargiu AV; Kwasny SM; Nguyen ST; Kim HS; Ding X; Ornik AR; Ruggerone P; Bowlin TL; Nikaido H; Pos KM; Opperman TJ
Proc Natl Acad Sci U S A; 2016 Mar; 113(13):3509-14. PubMed ID: 26976576
[TBL] [Abstract][Full Text] [Related]
3. The AcrB efflux pump: conformational cycling and peristalsis lead to multidrug resistance.
Seeger MA; Diederichs K; Eicher T; Brandstätter L; Schiefner A; Verrey F; Pos KM
Curr Drug Targets; 2008 Sep; 9(9):729-49. PubMed ID: 18781920
[TBL] [Abstract][Full Text] [Related]
4. RND efflux pumps: structural information translated into function and inhibition mechanisms.
Ruggerone P; Murakami S; Pos KM; Vargiu AV
Curr Top Med Chem; 2013; 13(24):3079-100. PubMed ID: 24200360
[TBL] [Abstract][Full Text] [Related]
5. Computer simulations suggest direct and stable tip to tip interaction between the outer membrane channel TolC and the isolated docking domain of the multidrug RND efflux transporter AcrB.
Schmidt TH; Raunest M; Fischer N; Reith D; Kandt C
Biochim Biophys Acta; 2016 Jul; 1858(7 Pt A):1419-26. PubMed ID: 27045078
[TBL] [Abstract][Full Text] [Related]
6. Chlorpromazine and Amitriptyline Are Substrates and Inhibitors of the AcrB Multidrug Efflux Pump.
Grimsey EM; Fais C; Marshall RL; Ricci V; Ciusa ML; Stone JW; Ivens A; Malloci G; Ruggerone P; Vargiu AV; Piddock LJV
mBio; 2020 Jun; 11(3):. PubMed ID: 32487753
[TBL] [Abstract][Full Text] [Related]
7. Drug transport mechanism of the AcrB efflux pump.
Pos KM
Biochim Biophys Acta; 2009 May; 1794(5):782-93. PubMed ID: 19166984
[TBL] [Abstract][Full Text] [Related]
8. The pseudo-atomic structure of an RND-type tripartite multidrug efflux pump.
Du D; Voss J; Wang Z; Chiu W; Luisi BF
Biol Chem; 2015 Sep; 396(9-10):1073-82. PubMed ID: 25803077
[TBL] [Abstract][Full Text] [Related]
9. Kinetic analysis of the inhibition of the drug efflux protein AcrB using surface plasmon resonance.
Mowla R; Wang Y; Ma S; Venter H
Biochim Biophys Acta Biomembr; 2018 Apr; 1860(4):878-886. PubMed ID: 28890187
[TBL] [Abstract][Full Text] [Related]
10. Pyridylpiperazine-based allosteric inhibitors of RND-type multidrug efflux pumps.
Plé C; Tam HK; Vieira Da Cruz A; Compagne N; Jiménez-Castellanos JC; Müller RT; Pradel E; Foong WE; Malloci G; Ballée A; Kirchner MA; Moshfegh P; Herledan A; Herrmann A; Deprez B; Willand N; Vargiu AV; Pos KM; Flipo M; Hartkoorn RC
Nat Commun; 2022 Jan; 13(1):115. PubMed ID: 35013254
[TBL] [Abstract][Full Text] [Related]
11. AcrB drug-binding pocket substitution confers clinically relevant resistance and altered substrate specificity.
Blair JM; Bavro VN; Ricci V; Modi N; Cacciotto P; Kleinekathӧfer U; Ruggerone P; Vargiu AV; Baylay AJ; Smith HE; Brandon Y; Galloway D; Piddock LJ
Proc Natl Acad Sci U S A; 2015 Mar; 112(11):3511-6. PubMed ID: 25737552
[TBL] [Abstract][Full Text] [Related]
12. Metabolomics Reveal Potential Natural Substrates of AcrB in Escherichia coli and Salmonella enterica Serovar Typhimurium.
Wang-Kan X; Rodríguez-Blanco G; Southam AD; Winder CL; Dunn WB; Ivens A; Piddock LJV
mBio; 2021 Mar; 12(2):. PubMed ID: 33785633
[TBL] [Abstract][Full Text] [Related]
13. Substrate specificity of the RND-type multidrug efflux pumps AcrB and AcrD of Escherichia coli is determined predominantly by two large periplasmic loops.
Elkins CA; Nikaido H
J Bacteriol; 2002 Dec; 184(23):6490-8. PubMed ID: 12426336
[TBL] [Abstract][Full Text] [Related]
14. Structural and functional aspects of the multidrug efflux pump AcrB.
Eicher T; Brandstätter L; Pos KM
Biol Chem; 2009 Aug; 390(8):693-9. PubMed ID: 19453279
[TBL] [Abstract][Full Text] [Related]
15. Evaluation of a series of 2-napthamide derivatives as inhibitors of the drug efflux pump AcrB for the reversal of antimicrobial resistance.
Wang Y; Mowla R; Guo L; Ogunniyi AD; Rahman T; De Barros Lopes MA; Ma S; Venter H
Bioorg Med Chem Lett; 2017 Feb; 27(4):733-739. PubMed ID: 28129976
[TBL] [Abstract][Full Text] [Related]
16. Allosteric drug transport mechanism of multidrug transporter AcrB.
Tam HK; Foong WE; Oswald C; Herrmann A; Zeng H; Pos KM
Nat Commun; 2021 Jun; 12(1):3889. PubMed ID: 34188038
[TBL] [Abstract][Full Text] [Related]
17. Molecular Interactions of Carbapenem Antibiotics with the Multidrug Efflux Transporter AcrB of
Atzori A; Malloci G; Cardamone F; Bosin A; Vargiu AV; Ruggerone P
Int J Mol Sci; 2020 Jan; 21(3):. PubMed ID: 32013182
[TBL] [Abstract][Full Text] [Related]
18. AcrB-AcrA Fusion Proteins That Act as Multidrug Efflux Transporters.
Hayashi K; Nakashima R; Sakurai K; Kitagawa K; Yamasaki S; Nishino K; Yamaguchi A
J Bacteriol; 2016 Jan; 198(2):332-42. PubMed ID: 26527645
[TBL] [Abstract][Full Text] [Related]
19. Structure of the AcrAB-TolC multidrug efflux pump.
Du D; Wang Z; James NR; Voss JE; Klimont E; Ohene-Agyei T; Venter H; Chiu W; Luisi BF
Nature; 2014 May; 509(7501):512-5. PubMed ID: 24747401
[TBL] [Abstract][Full Text] [Related]
20. Structures of Gate Loop Variants of the AcrB Drug Efflux Pump Bound by Erythromycin Substrate.
Ababou A; Koronakis V
PLoS One; 2016; 11(7):e0159154. PubMed ID: 27403665
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]