BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

223 related articles for article (PubMed ID: 31590180)

  • 1. Reversal of peripheral nerve injury-induced neuropathic pain and cognitive dysfunction via genetic and tomivosertib targeting of MNK.
    Shiers S; Mwirigi J; Pradhan G; Kume M; Black B; Barragan-Iglesias P; Moy JK; Dussor G; Pancrazio JJ; Kroener S; Price TJ
    Neuropsychopharmacology; 2020 Feb; 45(3):524-533. PubMed ID: 31590180
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Neuropathic Pain Creates an Enduring Prefrontal Cortex Dysfunction Corrected by the Type II Diabetic Drug Metformin But Not by Gabapentin.
    Shiers S; Pradhan G; Mwirigi J; Mejia G; Ahmad A; Kroener S; Price T
    J Neurosci; 2018 Aug; 38(33):7337-7350. PubMed ID: 30030404
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Nociceptor Translational Profiling Reveals the Ragulator-Rag GTPase Complex as a Critical Generator of Neuropathic Pain.
    Megat S; Ray PR; Moy JK; Lou TF; Barragán-Iglesias P; Li Y; Pradhan G; Wanghzou A; Ahmad A; Burton MD; North RY; Dougherty PM; Khoutorsky A; Sonenberg N; Webster KR; Dussor G; Campbell ZT; Price TJ
    J Neurosci; 2019 Jan; 39(3):393-411. PubMed ID: 30459229
    [TBL] [Abstract][Full Text] [Related]  

  • 4. IL-6 induced upregulation of T-type Ca
    Jeevakumar V; Al Sardar AK; Mohamed F; Smithhart CM; Price T; Dussor G
    J Neurophysiol; 2020 Jul; 124(1):274-283. PubMed ID: 32519575
    [TBL] [Abstract][Full Text] [Related]  

  • 5. MNK inhibitor eFT508 (Tomivosertib) suppresses ectopic activity in human dorsal root ganglion neurons from dermatomes with radicular neuropathic pain.
    Li Y; Uhelski ML; North RY; Mwirigi JM; Tatsui CE; Cata JP; Corrales G; Price TJ; Dougherty PM
    bioRxiv; 2023 Jun; ():. PubMed ID: 37398249
    [TBL] [Abstract][Full Text] [Related]  

  • 6. A Highly Selective MNK Inhibitor Rescues Deficits Associated with Fragile X Syndrome in Mice.
    Shukla T; de la Peña JB; Perish JM; Ploski JE; Stumpf CR; Webster KR; Thorn CA; Campbell ZT
    Neurotherapeutics; 2021 Jan; 18(1):624-639. PubMed ID: 33006091
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The MNK-eIF4E Signaling Axis Contributes to Injury-Induced Nociceptive Plasticity and the Development of Chronic Pain.
    Moy JK; Khoutorsky A; Asiedu MN; Black BJ; Kuhn JL; Barragán-Iglesias P; Megat S; Burton MD; Burgos-Vega CC; Melemedjian OK; Boitano S; Vagner J; Gkogkas CG; Pancrazio JJ; Mogil JS; Dussor G; Sonenberg N; Price TJ
    J Neurosci; 2017 Aug; 37(31):7481-7499. PubMed ID: 28674170
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Delayed inhibition of ERK and p38 attenuates neuropathic pain without affecting motor function recovery after peripheral nerve injury.
    Huang S; Chen Y; Jia Y; Yang T; Su W; Zhu Z; Xue P; Feng F; Zhao Y; Chen G
    Neuropharmacology; 2022 Jan; 202():108835. PubMed ID: 34648772
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Dual leucine zipper kinase is required for mechanical allodynia and microgliosis after nerve injury.
    Wlaschin JJ; Gluski JM; Nguyen E; Silberberg H; Thompson JH; Chesler AT; Le Pichon CE
    Elife; 2018 Jul; 7():. PubMed ID: 29968565
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Peripheral Neuropathy Induces HCN Channel Dysfunction in Pyramidal Neurons of the Medial Prefrontal Cortex.
    Cordeiro Matos S; Zhang Z; Séguéla P
    J Neurosci; 2015 Sep; 35(38):13244-56. PubMed ID: 26400952
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Inhibition MNK-eIF4E-β-catenin preferentially sensitizes gastric cancer to chemotherapy.
    Yang X; Liu Z; Yin X; Zeng Y; Guo G
    Fundam Clin Pharmacol; 2022 Aug; 36(4):712-720. PubMed ID: 35048413
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Role of lipocalin-2-chemokine axis in the development of neuropathic pain following peripheral nerve injury.
    Jeon S; Jha MK; Ock J; Seo J; Jin M; Cho H; Lee WH; Suk K
    J Biol Chem; 2013 Aug; 288(33):24116-27. PubMed ID: 23836894
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Interleukin-1β overproduction is a common cause for neuropathic pain, memory deficit, and depression following peripheral nerve injury in rodents.
    Gui WS; Wei X; Mai CL; Murugan M; Wu LJ; Xin WJ; Zhou LJ; Liu XG
    Mol Pain; 2016; 12():. PubMed ID: 27175012
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Targeting aurora kinase B alleviates spinal microgliosis and neuropathic pain in a rat model of peripheral nerve injury.
    Shen Y; Ding Z; Ma S; Zou Y; Yang X; Ding Z; Zhang Y; Zhu X; Schäfer MKE; Guo Q; Huang C
    J Neurochem; 2020 Jan; 152(1):72-91. PubMed ID: 31563141
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Inhibition of eukaryotic initiation factor 4E by tomivosertib suppresses angiogenesis, growth, and survival of glioblastoma and enhances chemotherapy's efficacy.
    Zhang Q; Zhao J; Xu T
    Fundam Clin Pharmacol; 2023 Aug; 37(4):807-815. PubMed ID: 36691859
    [TBL] [Abstract][Full Text] [Related]  

  • 16. MNK as a potential pharmacological target for suppressing LPS-induced acute lung injury in mice.
    Gao J; Teng L; Yang S; Huang S; Li L; Zhou L; Liu G; Tang H
    Biochem Pharmacol; 2021 Apr; 186():114499. PubMed ID: 33675774
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Electroacupuncture ameliorates mechanical hypersensitivity by down-regulating spinal Janus kinase 2/signal transducer and activation of transcription 3 and interleukin 6 in rats with spared nerve injury.
    Wang Y; Xia YY; Xue M; Jiang Q; Huang Z; Huang C
    Acupunct Med; 2021 Aug; 39(4):358-366. PubMed ID: 32744065
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Inhibition of the protein kinase IKKepsilon attenuates neuropathic pain in mice.
    Möser CV; Möller M; Fleck SC; Thomas D; Geisslinger G; Niederberger E
    Neuropharmacology; 2019 Mar; 146():198-211. PubMed ID: 30528326
    [TBL] [Abstract][Full Text] [Related]  

  • 19. TNF-α Differentially Regulates Synaptic Plasticity in the Hippocampus and Spinal Cord by Microglia-Dependent Mechanisms after Peripheral Nerve Injury.
    Liu Y; Zhou LJ; Wang J; Li D; Ren WJ; Peng J; Wei X; Xu T; Xin WJ; Pang RP; Li YY; Qin ZH; Murugan M; Mattson MP; Wu LJ; Liu XG
    J Neurosci; 2017 Jan; 37(4):871-881. PubMed ID: 28123022
    [TBL] [Abstract][Full Text] [Related]  

  • 20. eIF4E phosphorylation regulates ongoing pain, independently of inflammation, and hyperalgesic priming in the mouse CFA model.
    Moy JK; Kuhn JL; Szabo-Pardi TA; Pradhan G; Price TJ
    Neurobiol Pain; 2018; 4():45-50. PubMed ID: 30211343
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.