354 related articles for article (PubMed ID: 31594641)
21. Combined BET bromodomain and CDK2 inhibition in MYC-driven medulloblastoma.
Bolin S; Borgenvik A; Persson CU; Sundström A; Qi J; Bradner JE; Weiss WA; Cho YJ; Weishaupt H; Swartling FJ
Oncogene; 2018 May; 37(21):2850-2862. PubMed ID: 29511348
[TBL] [Abstract][Full Text] [Related]
22. PP2A inhibition with LB100 enhances cisplatin cytotoxicity and overcomes cisplatin resistance in medulloblastoma cells.
Ho WS; Feldman MJ; Maric D; Amable L; Hall MD; Feldman GM; Ray-Chaudhury A; Lizak MJ; Vera JC; Robison RA; Zhuang Z; Heiss JD
Oncotarget; 2016 Mar; 7(11):12447-63. PubMed ID: 26799670
[TBL] [Abstract][Full Text] [Related]
23. PI-3K Inhibitors Preferentially Target CD15+ Cancer Stem Cell Population in SHH Driven Medulloblastoma.
Singh AR; Joshi S; Zulcic M; Alcaraz M; Garlich JR; Morales GA; Cho YJ; Bao L; Levy ML; Newbury R; Malicki D; Messer K; Crawford J; Durden DL
PLoS One; 2016; 11(3):e0150836. PubMed ID: 26938241
[TBL] [Abstract][Full Text] [Related]
24. The bromodomain protein Brd4 is a positive regulatory component of P-TEFb and stimulates RNA polymerase II-dependent transcription.
Jang MK; Mochizuki K; Zhou M; Jeong HS; Brady JN; Ozato K
Mol Cell; 2005 Aug; 19(4):523-34. PubMed ID: 16109376
[TBL] [Abstract][Full Text] [Related]
25. Cross-talk among RNA polymerase II kinases modulates C-terminal domain phosphorylation.
Devaiah BN; Singer DS
J Biol Chem; 2012 Nov; 287(46):38755-66. PubMed ID: 23027873
[TBL] [Abstract][Full Text] [Related]
26. Flavopiridol induces phosphorylation of AKT in a human glioblastoma cell line, in contrast to siRNA-mediated silencing of Cdk9: Implications for drug design and development.
Caracciolo V; Laurenti G; Romano G; Carnevale V; Cimini AM; Crozier-Fitzgerald C; Gentile Warschauer E; Russo G; Giordano A
Cell Cycle; 2012 Mar; 11(6):1202-16. PubMed ID: 22391209
[TBL] [Abstract][Full Text] [Related]
27. EBV EBNA 2 stimulates CDK9-dependent transcription and RNA polymerase II phosphorylation on serine 5.
Bark-Jones SJ; Webb HM; West MJ
Oncogene; 2006 Mar; 25(12):1775-85. PubMed ID: 16314842
[TBL] [Abstract][Full Text] [Related]
28. BRD4 Couples NF-κB/RelA with Airway Inflammation and the IRF-RIG-I Amplification Loop in Respiratory Syncytial Virus Infection.
Tian B; Yang J; Zhao Y; Ivanciuc T; Sun H; Garofalo RP; Brasier AR
J Virol; 2017 Mar; 91(6):. PubMed ID: 28077651
[TBL] [Abstract][Full Text] [Related]
29. CDK9-dependent transcriptional elongation in the innate interferon-stimulated gene response to respiratory syncytial virus infection in airway epithelial cells.
Tian B; Zhao Y; Kalita M; Edeh CB; Paessler S; Casola A; Teng MN; Garofalo RP; Brasier AR
J Virol; 2013 Jun; 87(12):7075-92. PubMed ID: 23596302
[TBL] [Abstract][Full Text] [Related]
30. Suppression of STAT3 NH
Ray S; Coulter DW; Gray SD; Sughroue JA; Roychoudhury S; McIntyre EM; Chaturvedi NK; Bhakat KK; Joshi SS; McGuire TR; Sharp JG
Mol Carcinog; 2018 Apr; 57(4):536-548. PubMed ID: 29280516
[TBL] [Abstract][Full Text] [Related]
31. Regulation of P-TEFb elongation complex activity by CDK9 acetylation.
Fu J; Yoon HG; Qin J; Wong J
Mol Cell Biol; 2007 Jul; 27(13):4641-51. PubMed ID: 17452463
[TBL] [Abstract][Full Text] [Related]
32. A Novel Combination Approach Targeting an Enhanced Protein Synthesis Pathway in MYC-driven (Group 3) Medulloblastoma.
Chaturvedi NK; Kling MJ; Griggs CN; Kesherwani V; Shukla M; McIntyre EM; Ray S; Liu Y; McGuire TR; Sharp JG; Band H; Joshi SS; Coulter DW
Mol Cancer Ther; 2020 Jun; 19(6):1351-1362. PubMed ID: 32371591
[TBL] [Abstract][Full Text] [Related]
33. Systematic Kinase Inhibitor Profiling Identifies CDK9 as a Synthetic Lethal Target in NUT Midline Carcinoma.
Brägelmann J; Dammert MA; Dietlein F; Heuckmann JM; Choidas A; Böhm S; Richters A; Basu D; Tischler V; Lorenz C; Habenberger P; Fang Z; Ortiz-Cuaran S; Leenders F; Eickhoff J; Koch U; Getlik M; Termathe M; Sallouh M; Greff Z; Varga Z; Balke-Want H; French CA; Peifer M; Reinhardt HC; Örfi L; Kéri G; Ansén S; Heukamp LC; Büttner R; Rauh D; Klebl BM; Thomas RK; Sos ML
Cell Rep; 2017 Sep; 20(12):2833-2845. PubMed ID: 28930680
[TBL] [Abstract][Full Text] [Related]
34. Cyclin-dependent kinase 9 (CDK9) is a novel prognostic marker and therapeutic target in osteosarcoma.
Ma H; Seebacher NA; Hornicek FJ; Duan Z
EBioMedicine; 2019 Jan; 39():182-193. PubMed ID: 30579871
[TBL] [Abstract][Full Text] [Related]
35. Cdk9 is an essential kinase in Drosophila that is required for heat shock gene expression, histone methylation and elongation factor recruitment.
Eissenberg JC; Shilatifard A; Dorokhov N; Michener DE
Mol Genet Genomics; 2007 Feb; 277(2):101-14. PubMed ID: 17001490
[TBL] [Abstract][Full Text] [Related]
36. Phosphorylation by cyclin-dependent kinase-9 controls ubiquitin-conjugating enzyme-2A function.
Shchebet A; Karpiuk O; Kremmer E; Eick D; Johnsen SA
Cell Cycle; 2012 Jun; 11(11):2122-7. PubMed ID: 22592529
[TBL] [Abstract][Full Text] [Related]
37. The Establishment of a Hyperactive Structure Allows the Tumour Suppressor Protein p53 to Function through P-TEFb during Limited CDK9 Kinase Inhibition.
Albert TK; Antrecht C; Kremmer E; Meisterernst M
PLoS One; 2016; 11(1):e0146648. PubMed ID: 26745862
[TBL] [Abstract][Full Text] [Related]
38. JMJD5 couples with CDK9 to release the paused RNA polymerase II.
Liu H; Ramachandran S; Fong N; Phang T; Lee S; Parsa P; Liu X; Harmacek L; Danhorn T; Song T; Oh S; Zhang Q; Chen Z; Zhang Q; Tu TH; Happoldt C; O'Conner B; Janknecht R; Li CY; Marrack P; Kappler J; Leach S; Zhang G
Proc Natl Acad Sci U S A; 2020 Aug; 117(33):19888-19895. PubMed ID: 32747552
[TBL] [Abstract][Full Text] [Related]
39. Cdk9 phosphorylates p53 on serine 392 independently of CKII.
Claudio PP; Cui J; Ghafouri M; Mariano C; White MK; Safak M; Sheffield JB; Giordano A; Khalili K; Amini S; Sawaya BE
J Cell Physiol; 2006 Sep; 208(3):602-12. PubMed ID: 16741955
[TBL] [Abstract][Full Text] [Related]
40. Discovery and SAR of novel pyrazolo[1,5-a]pyrimidines as inhibitors of CDK9.
Phillipson LJ; Segal DH; Nero TL; Parker MW; Wan SS; de Silva M; Guthridge MA; Wei AH; Burns CJ
Bioorg Med Chem; 2015 Oct; 23(19):6280-96. PubMed ID: 26349627
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]