169 related articles for article (PubMed ID: 31598093)
1. Structure-Based Design, Synthesis and Biological Evaluation of Bis-Tetrahydropyran Furan Acetogenin Mimics Targeting the Trypanosomatid F1 Component of ATP Synthase.
Zacharova MK; Tulloch LB; Gould ER; Fraser AL; King EF; Menzies SK; Smith TK; Florence GJ
European J Org Chem; 2019 Sep; 2019(31-32):5434-5440. PubMed ID: 31598093
[TBL] [Abstract][Full Text] [Related]
2. Photo-affinity labelling and biochemical analyses identify the target of trypanocidal simplified natural product analogues.
Tulloch LB; Menzies SK; Fraser AL; Gould ER; King EF; Zacharova MK; Florence GJ; Smith TK
PLoS Negl Trop Dis; 2017 Sep; 11(9):e0005886. PubMed ID: 28873407
[TBL] [Abstract][Full Text] [Related]
3. Simplifying nature: Towards the design of broad spectrum kinetoplastid inhibitors, inspired by acetogenins.
Gould ER; King EFB; Menzies SK; Fraser AL; Tulloch LB; Zacharova MK; Smith TK; Florence GJ
Bioorg Med Chem; 2017 Nov; 25(22):6126-6136. PubMed ID: 28185724
[TBL] [Abstract][Full Text] [Related]
4. Non-natural acetogenin analogues as potent Trypanosoma brucei inhibitors.
Florence GJ; Fraser AL; Gould ER; King EF; Menzies SK; Morris JC; Tulloch LB; Smith TK
ChemMedChem; 2014 Nov; 9(11):2548-56. PubMed ID: 25145275
[TBL] [Abstract][Full Text] [Related]
5. New multifunctional Ru(II) organometallic compounds show activity against Trypanosoma brucei and Leishmania infantum.
Rivas F; Del Mármol C; Scalese G; Pérez-Díaz L; Machado I; Blacque O; Medeiros A; Comini M; Gambino D
J Inorg Biochem; 2022 Dec; 237():112016. PubMed ID: 36244312
[TBL] [Abstract][Full Text] [Related]
6. Multicomponent reaction-based synthesis and biological evaluation of tricyclic heterofused quinolines with multi-trypanosomatid activity.
Di Pietro O; Vicente-García E; Taylor MC; Berenguer D; Viayna E; Lanzoni A; Sola I; Sayago H; Riera C; Fisa R; Clos MV; Pérez B; Kelly JM; Lavilla R; Muñoz-Torrero D
Eur J Med Chem; 2015 Nov; 105():120-37. PubMed ID: 26479031
[TBL] [Abstract][Full Text] [Related]
7. Design and Synthesis of Broad Spectrum Trypanosomatid Selective Inhibitors.
Fraser AL; Menzies SK; King EFB; Tulloch LB; Gould ER; Zacharova MK; Smith TK; Florence GJ
ACS Infect Dis; 2018 Apr; 4(4):560-567. PubMed ID: 29313667
[TBL] [Abstract][Full Text] [Related]
8. In vitro evaluation of arylsubstituted imidazoles derivatives as antiprotozoal agents and docking studies on sterol 14α-demethylase (CYP51) from Trypanosoma cruzi, Leishmania infantum, and Trypanosoma brucei.
Rojas Vargas JA; López AG; Pérez Y; Cos P; Froeyen M
Parasitol Res; 2019 May; 118(5):1533-1548. PubMed ID: 30903349
[TBL] [Abstract][Full Text] [Related]
9. Chemical Cartography Approaches to Study Trypanosomatid Infection.
Dean DA; Haffner JJ; Katemauswa M; McCall LI
J Vis Exp; 2022 Jan; (179):. PubMed ID: 35129167
[TBL] [Abstract][Full Text] [Related]
10. Synthesis and SAR of new isoxazole-triazole bis-heterocyclic compounds as analogues of natural lignans with antiparasitic activity.
Zimmermann LA; de Moraes MH; da Rosa R; de Melo EB; Paula FR; Schenkel EP; Steindel M; Bernardes LSC
Bioorg Med Chem; 2018 Sep; 26(17):4850-4862. PubMed ID: 30173929
[TBL] [Abstract][Full Text] [Related]
11. Comparative analysis of the kinomes of three pathogenic trypanosomatids: Leishmania major, Trypanosoma brucei and Trypanosoma cruzi.
Parsons M; Worthey EA; Ward PN; Mottram JC
BMC Genomics; 2005 Sep; 6():127. PubMed ID: 16164760
[TBL] [Abstract][Full Text] [Related]
12. Exploring N-myristoyltransferase as a promising drug target against parasitic neglected tropical diseases.
Nascimento IJDS; Cavalcanti MAT; de Moura RO
Eur J Med Chem; 2023 Oct; 258():115550. PubMed ID: 37336067
[TBL] [Abstract][Full Text] [Related]
13. The use of Sulfonamide Derivatives in the Treatment of Trypanosomatid Parasites including Trypanosoma cruzi, Trypanosoma brucei, and Leishmania ssp.
Scarim CB; Chelucci RC; Dos Santos JL; Chin CM
Med Chem; 2020; 16(1):24-38. PubMed ID: 31218962
[TBL] [Abstract][Full Text] [Related]
14. Naphthoquinones and Derivatives for Chemotherapy: Perspectives and Limitations of their Anti-trypanosomatids Activities.
Dantas-Pereira L; Cunha-Junior EF; Andrade-Neto VV; Bower JF; Jardim GAM; da Silva Júnior EN; Torres-Santos EC; Menna-Barreto RFS
Curr Pharm Des; 2021; 27(15):1807-1824. PubMed ID: 33167829
[TBL] [Abstract][Full Text] [Related]
15. Design, synthesis and biological evaluation of potent azadipeptide nitrile inhibitors and activity-based probes as promising anti-Trypanosoma brucei agents.
Yang PY; Wang M; Li L; Wu H; He CY; Yao SQ
Chemistry; 2012 May; 18(21):6528-41. PubMed ID: 22488888
[TBL] [Abstract][Full Text] [Related]
16. VLP-Based Vaccines as a Suitable Technology to Target Trypanosomatid Diseases.
Queiroz AMV; Oliveira JWF; Moreno CJ; Guérin DMA; Silva MS
Vaccines (Basel); 2021 Mar; 9(3):. PubMed ID: 33807516
[TBL] [Abstract][Full Text] [Related]
17. Rapid, Selection-Free, High-Efficiency Genome Editing in Protozoan Parasites Using CRISPR-Cas9 Ribonucleoproteins.
Soares Medeiros LC; South L; Peng D; Bustamante JM; Wang W; Bunkofske M; Perumal N; Sanchez-Valdez F; Tarleton RL
mBio; 2017 Nov; 8(6):. PubMed ID: 29114029
[TBL] [Abstract][Full Text] [Related]
18. Targeting calcium homeostasis as the therapy of Chagas' disease and leishmaniasis - a review.
Benaim B; Garcia CR
Trop Biomed; 2011 Dec; 28(3):471-81. PubMed ID: 22433874
[TBL] [Abstract][Full Text] [Related]
19. Anilinoquinoline based inhibitors of trypanosomatid proliferation.
Ferrins L; Sharma A; Thomas SM; Mehta N; Erath J; Tanghe S; Leed SE; Rodriguez A; Mensa-Wilmot K; Sciotti RJ; Gillingwater K; Pollastri MP
PLoS Negl Trop Dis; 2018 Nov; 12(11):e0006834. PubMed ID: 30475800
[TBL] [Abstract][Full Text] [Related]
20. Total synthesis, stereochemical assignment, and biological activity of chamuvarinin and structural analogues.
Florence GJ; Morris JC; Murray RG; Vanga RR; Osler JD; Smith TK
Chemistry; 2013 Jun; 19(25):8309-20. PubMed ID: 23630031
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]