125 related articles for article (PubMed ID: 31599956)
1. NLRC4 Mutation in flagellin-derived peptide CBLB502 ligand-binding domain reduces the inflammatory response but not radioprotective activity.
Lai L; Yang G; Yao X; Wang L; Zhan Y; Yu M; Yin R; Li C; Yang X; Ge C
J Radiat Res; 2019 Nov; 60(6):780-785. PubMed ID: 31599956
[TBL] [Abstract][Full Text] [Related]
2. Central role of liver in anticancer and radioprotective activities of Toll-like receptor 5 agonist.
Burdelya LG; Brackett CM; Kojouharov B; Gitlin II; Leonova KI; Gleiberman AS; Aygun-Sunar S; Veith J; Johnson C; Haderski GJ; Stanhope-Baker P; Allamaneni S; Skitzki J; Zeng M; Martsen E; Medvedev A; Scheblyakov D; Artemicheva NM; Logunov DY; Gintsburg AL; Naroditsky BS; Makarov SS; Gudkov AV
Proc Natl Acad Sci U S A; 2013 May; 110(20):E1857-66. PubMed ID: 23630282
[TBL] [Abstract][Full Text] [Related]
3. Toll-like receptor 5 agonist CBLB502 induces radioprotective effects in vitro.
Shi T; Li L; Zhou G; Wang C; Chen X; Zhang R; Xu J; Lu X; Jiang H; Chen J
Acta Biochim Biophys Sin (Shanghai); 2017 Jun; 49(6):487-495. PubMed ID: 28407032
[TBL] [Abstract][Full Text] [Related]
4. An agonist of toll-like receptor 5 has radioprotective activity in mouse and primate models.
Burdelya LG; Krivokrysenko VI; Tallant TC; Strom E; Gleiberman AS; Gupta D; Kurnasov OV; Fort FL; Osterman AL; Didonato JA; Feinstein E; Gudkov AV
Science; 2008 Apr; 320(5873):226-30. PubMed ID: 18403709
[TBL] [Abstract][Full Text] [Related]
5. TLR5 binding and activation by KMRC011, a flagellin-derived radiation countermeasure.
Song WS; Kim JH; Choi CM; Lee WJ; Yoon SI
Biochem Biophys Res Commun; 2019 Jan; 508(2):570-575. PubMed ID: 30509486
[TBL] [Abstract][Full Text] [Related]
6. TLR5 or NLRC4 is necessary and sufficient for promotion of humoral immunity by flagellin.
Vijay-Kumar M; Carvalho FA; Aitken JD; Fifadara NH; Gewirtz AT
Eur J Immunol; 2010 Dec; 40(12):3528-34. PubMed ID: 21072873
[TBL] [Abstract][Full Text] [Related]
7. Activation of NLRC4 downregulates TLR5-mediated antibody immune responses against flagellin.
Li W; Yang J; Zhang E; Zhong M; Xiao Y; Yu J; Zhou D; Cao Y; Yang Y; Li Y; Yan H
Cell Mol Immunol; 2016 Jul; 13(4):514-23. PubMed ID: 25914934
[TBL] [Abstract][Full Text] [Related]
8. The role of TRIF protein in regulating the proliferation and antigen presentation ability of myeloid dendritic cells through the ERK1/2 signaling pathway in chronic low-grade inflammation of intestinal mucosa mediated by flagellin-TLR5 complex signal.
Zhuang Z; Chen Y; Zheng J; Chen S
PeerJ; 2024; 12():e16716. PubMed ID: 38188180
[TBL] [Abstract][Full Text] [Related]
9. A flagellin-derived toll-like receptor 5 agonist stimulates cytotoxic lymphocyte-mediated tumor immunity.
Leigh ND; Bian G; Ding X; Liu H; Aygun-Sunar S; Burdelya LG; Gudkov AV; Cao X
PLoS One; 2014; 9(1):e85587. PubMed ID: 24454895
[TBL] [Abstract][Full Text] [Related]
10. Nucleotide-binding oligomerization domain containing-like receptor family, caspase recruitment domain (CARD) containing 4 (NLRC4) regulates intrapulmonary replication of aerosolized Legionella pneumophila.
Berrington WR; Smith KD; Skerrett SJ; Hawn TR
BMC Infect Dis; 2013 Aug; 13():371. PubMed ID: 23937571
[TBL] [Abstract][Full Text] [Related]
11. CBLB502 administration protects gut mucosal tissue in ulcerative colitis by inhibiting inflammation.
Xu Y; Dong H; Ge C; Gao Y; Liu H; Li W; Zhang C
Ann Transl Med; 2016 Aug; 4(16):301. PubMed ID: 27668221
[TBL] [Abstract][Full Text] [Related]
12.
Chebly H; Marvaud JC; Safa L; Elkak AK; Kobeissy PH; Kansau I; Larrazet C
Int J Mol Sci; 2022 Oct; 23(20):. PubMed ID: 36293218
[No Abstract] [Full Text] [Related]
13. Redundant and cooperative interactions between TLR5 and NLRC4 in protective lung mucosal immunity against Pseudomonas aeruginosa.
Tolle L; Yu FS; Kovach MA; Ballinger MN; Newstead MW; Zeng X; Nunez G; Standiford TJ
J Innate Immun; 2015; 7(2):177-86. PubMed ID: 25402425
[TBL] [Abstract][Full Text] [Related]
14. CBLB502, a Toll-like receptor 5 agonist, offers protection against radiation-induced male reproductive system damage in mice.
Bai H; Sun F; Yang G; Wang L; Zhang Q; Zhang Q; Zhan Y; Chen J; Yu M; Li C; Yin R; Yang X; Ge C
Biol Reprod; 2019 Jan; 100(1):281-291. PubMed ID: 30084935
[TBL] [Abstract][Full Text] [Related]
15. Toll-like Receptor Agonist CBLB502 Protects Against Radiation-induced Intestinal Injury in Mice.
Wang Q; Duan J; Hong J; Ding K; Tai F; Zhu J; Fu H; Zheng X; Ge C
In Vivo; 2024; 38(4):1636-1648. PubMed ID: 38936936
[TBL] [Abstract][Full Text] [Related]
16. CBLB502, an agonist of Toll-like receptor 5, has antioxidant and scavenging free radicals activities in vitro.
Li W; Ge C; Yang L; Wang R; Lu Y; Gao Y; Li Z; Wu Y; Zheng X; Wang Z; Zhang C
Int J Biol Macromol; 2016 Jan; 82():97-103. PubMed ID: 26476243
[TBL] [Abstract][Full Text] [Related]
17. Synergistic effect of the TLR5 agonist CBLB502 and its downstream effector IL-22 against liver injury.
Melin N; Sánchez-Taltavull D; Fahrner R; Keogh A; Dosch M; Büchi I; Zimmer Y; Medová M; Beldi G; Aebersold DM; Candinas D; Stroka D
Cell Death Dis; 2021 Apr; 12(4):366. PubMed ID: 33824326
[TBL] [Abstract][Full Text] [Related]
18. Structural basis of TLR5-flagellin recognition and signaling.
Yoon SI; Kurnasov O; Natarajan V; Hong M; Gudkov AV; Osterman AL; Wilson IA
Science; 2012 Feb; 335(6070):859-64. PubMed ID: 22344444
[TBL] [Abstract][Full Text] [Related]
19. Identification of conserved domains in Salmonella muenchen flagellin that are essential for its ability to activate TLR5 and to induce an inflammatory response in vitro.
Murthy KG; Deb A; Goonesekera S; Szabó C; Salzman AL
J Biol Chem; 2004 Feb; 279(7):5667-75. PubMed ID: 14634022
[TBL] [Abstract][Full Text] [Related]
20. Identification of granulocyte colony-stimulating factor and interleukin-6 as candidate biomarkers of CBLB502 efficacy as a medical radiation countermeasure.
Krivokrysenko VI; Shakhov AN; Singh VK; Bone F; Kononov Y; Shyshynova I; Cheney A; Maitra RK; Purmal A; Whitnall MH; Gudkov AV; Feinstein E
J Pharmacol Exp Ther; 2012 Nov; 343(2):497-508. PubMed ID: 22837010
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]