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2. Cooperative Targeting of Immunotherapy-Resistant Melanoma and Lung Cancer by an AXL-Targeting Antibody-Drug Conjugate and Immune Checkpoint Blockade. Boshuizen J; Pencheva N; Krijgsman O; Altimari DD; Castro PG; de Bruijn B; Ligtenberg MA; Gresnigt-Van den Heuvel E; Vredevoogd DW; Song JY; Visser N; Apriamashvili G; Janmaat ML; Plantinga TS; Franken P; Houtkamp M; Lingnau A; Jure-Kunkel M; Peeper DS Cancer Res; 2021 Apr; 81(7):1775-1787. PubMed ID: 33531370 [TBL] [Abstract][Full Text] [Related]
3. Enapotamab Vedotin, an AXL-Specific Antibody-Drug Conjugate, Demonstrates Antitumor Efficacy in Patient-Derived Xenograft Models of Soft Tissue Sarcoma. Van Renterghem B; Wozniak A; Castro PG; Franken P; Pencheva N; Sciot R; Schöffski P Int J Mol Sci; 2022 Jul; 23(14):. PubMed ID: 35886842 [TBL] [Abstract][Full Text] [Related]
4. ONO-7475, a Novel AXL Inhibitor, Suppresses the Adaptive Resistance to Initial EGFR-TKI Treatment in Okura N; Nishioka N; Yamada T; Taniguchi H; Tanimura K; Katayama Y; Yoshimura A; Watanabe S; Kikuchi T; Shiotsu S; Kitazaki T; Nishiyama A; Iwasaku M; Kaneko Y; Uchino J; Uehara H; Horinaka M; Sakai T; Tanaka K; Kozaki R; Yano S; Takayama K Clin Cancer Res; 2020 May; 26(9):2244-2256. PubMed ID: 31953310 [TBL] [Abstract][Full Text] [Related]
5. Targeting the degradation of AXL receptor tyrosine kinase to overcome resistance in gefitinib-resistant non-small cell lung cancer. Bae SY; Hong JY; Lee HJ; Park HJ; Lee SK Oncotarget; 2015 Apr; 6(12):10146-60. PubMed ID: 25760142 [TBL] [Abstract][Full Text] [Related]
6. AXL degradation in combination with EGFR-TKI can delay and overcome acquired resistance in human non-small cell lung cancer cells. Kim D; Bach DH; Fan YH; Luu TT; Hong JY; Park HJ; Lee SK Cell Death Dis; 2019 May; 10(5):361. PubMed ID: 31043587 [TBL] [Abstract][Full Text] [Related]
7. Activation of AXL as a Preclinical Acquired Resistance Mechanism Against Osimertinib Treatment in Namba K; Shien K; Takahashi Y; Torigoe H; Sato H; Yoshioka T; Takeda T; Kurihara E; Ogoshi Y; Yamamoto H; Soh J; Tomida S; Toyooka S Mol Cancer Res; 2019 Feb; 17(2):499-507. PubMed ID: 30463991 [TBL] [Abstract][Full Text] [Related]
8. MET and AXL inhibitor NPS-1034 exerts efficacy against lung cancer cells resistant to EGFR kinase inhibitors because of MET or AXL activation. Rho JK; Choi YJ; Kim SY; Kim TW; Choi EK; Yoon SJ; Park BM; Park E; Bae JH; Choi CM; Lee JC Cancer Res; 2014 Jan; 74(1):253-62. PubMed ID: 24165158 [TBL] [Abstract][Full Text] [Related]
9. Mutant-Selective Irreversible EGFR Inhibitor, Naquotinib, Inhibits Tumor Growth in NSCLC Models with EGFR-Activating Mutations, T790M Mutation, and AXL Overexpression. Tanaka H; Sakagami H; Kaneko N; Konagai S; Yamamoto H; Matsuya T; Yuri M; Yamanaka Y; Mori M; Takeuchi M; Koshio H; Hirano M; Kuromitsu S Mol Cancer Ther; 2019 Aug; 18(8):1366-1373. PubMed ID: 31092564 [TBL] [Abstract][Full Text] [Related]
10. Mechanism research of miR-34a regulates Axl in non-small-cell lung cancer with gefitinib-acquired resistance. Xiong R; Sun XX; Wu HR; Xu GW; Wang GX; Sun XH; Xu MQ; Xie MR Thorac Cancer; 2020 Jan; 11(1):156-165. PubMed ID: 31777195 [TBL] [Abstract][Full Text] [Related]
11. Development of the phenylpyrazolo[3,4- Lee HJ; Pham PC; Pei H; Lim B; Hyun SY; Baek B; Kim B; Kim Y; Kim MH; Kang NW; Min HY; Kim DD; Lee J; Lee HY Theranostics; 2021; 11(4):1918-1936. PubMed ID: 33408789 [No Abstract] [Full Text] [Related]
12. Combined effect of cabozantinib and gefitinib in crizotinib-resistant lung tumors harboring ROS1 fusions. Kato Y; Ninomiya K; Ohashi K; Tomida S; Makimoto G; Watanabe H; Kudo K; Matsumoto S; Umemura S; Goto K; Ichihara E; Ninomiya T; Kubo T; Sato A; Hotta K; Tabata M; Toyooka S; Maeda Y; Kiura K Cancer Sci; 2018 Oct; 109(10):3149-3158. PubMed ID: 30053332 [TBL] [Abstract][Full Text] [Related]
13. AXL mediates resistance to cetuximab therapy. Brand TM; Iida M; Stein AP; Corrigan KL; Braverman CM; Luthar N; Toulany M; Gill PS; Salgia R; Kimple RJ; Wheeler DL Cancer Res; 2014 Sep; 74(18):5152-64. PubMed ID: 25136066 [TBL] [Abstract][Full Text] [Related]
14. Common Co-activation of AXL and CDCP1 in EGFR-mutation-positive Non-smallcell Lung Cancer Associated With Poor Prognosis. Karachaliou N; Chaib I; Cardona AF; Berenguer J; Bracht JWP; Yang J; Cai X; Wang Z; Hu C; Drozdowskyj A; Servat CC; Servat JC; Ito M; Attili I; Aldeguer E; Capitan AG; Rodriguez J; Rojas L; Viteri S; Molina-Vila MA; Ou SI; Okada M; Mok TS; Bivona TG; Ono M; Cui J; Ramón Y Cajal S; Frias A; Cao P; Rosell R EBioMedicine; 2018 Mar; 29():112-127. PubMed ID: 29433983 [TBL] [Abstract][Full Text] [Related]
15. AXL/MET dual inhibitor, CB469, has activity in non-small cell lung cancer with acquired resistance to EGFR TKI with AXL or MET activation. Yang YM; Jang Y; Lee SH; Kang B; Lim SM Lung Cancer; 2020 Aug; 146():70-77. PubMed ID: 32521387 [TBL] [Abstract][Full Text] [Related]
16. An epithelial-mesenchymal transition gene signature predicts resistance to EGFR and PI3K inhibitors and identifies Axl as a therapeutic target for overcoming EGFR inhibitor resistance. Byers LA; Diao L; Wang J; Saintigny P; Girard L; Peyton M; Shen L; Fan Y; Giri U; Tumula PK; Nilsson MB; Gudikote J; Tran H; Cardnell RJ; Bearss DJ; Warner SL; Foulks JM; Kanner SB; Gandhi V; Krett N; Rosen ST; Kim ES; Herbst RS; Blumenschein GR; Lee JJ; Lippman SM; Ang KK; Mills GB; Hong WK; Weinstein JN; Wistuba II; Coombes KR; Minna JD; Heymach JV Clin Cancer Res; 2013 Jan; 19(1):279-90. PubMed ID: 23091115 [TBL] [Abstract][Full Text] [Related]
17. Cooperative targeting of melanoma heterogeneity with an AXL antibody-drug conjugate and BRAF/MEK inhibitors. Boshuizen J; Koopman LA; Krijgsman O; Shahrabi A; van den Heuvel EG; Ligtenberg MA; Vredevoogd DW; Kemper K; Kuilman T; Song JY; Pencheva N; Mortensen JT; Foppen MG; Rozeman EA; Blank CU; Janmaat ML; Satijn D; Breij ECW; Peeper DS; Parren PWHI Nat Med; 2018 Feb; 24(2):203-212. PubMed ID: 29334371 [TBL] [Abstract][Full Text] [Related]
18. AXL confers intrinsic resistance to osimertinib and advances the emergence of tolerant cells. Taniguchi H; Yamada T; Wang R; Tanimura K; Adachi Y; Nishiyama A; Tanimoto A; Takeuchi S; Araujo LH; Boroni M; Yoshimura A; Shiotsu S; Matsumoto I; Watanabe S; Kikuchi T; Miura S; Tanaka H; Kitazaki T; Yamaguchi H; Mukae H; Uchino J; Uehara H; Takayama K; Yano S Nat Commun; 2019 Jan; 10(1):259. PubMed ID: 30651547 [TBL] [Abstract][Full Text] [Related]
19. Axl-altered microRNAs regulate tumorigenicity and gefitinib resistance in lung cancer. Wang Y; Xia H; Zhuang Z; Miao L; Chen X; Cai H Cell Death Dis; 2014 May; 5(5):e1227. PubMed ID: 24832599 [TBL] [Abstract][Full Text] [Related]
20. Mer or Axl receptor tyrosine kinase inhibition promotes apoptosis, blocks growth and enhances chemosensitivity of human non-small cell lung cancer. Linger RM; Cohen RA; Cummings CT; Sather S; Migdall-Wilson J; Middleton DH; Lu X; Barón AE; Franklin WA; Merrick DT; Jedlicka P; DeRyckere D; Heasley LE; Graham DK Oncogene; 2013 Jul; 32(29):3420-31. PubMed ID: 22890323 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]