179 related articles for article (PubMed ID: 31600779)
1. PAICS deficiency, a new defect of de novo purine synthesis resulting in multiple congenital anomalies and fatal outcome.
Pelet A; Skopova V; Steuerwald U; Baresova V; Zarhrate M; Plaza JM; Hnizda A; Krijt M; Souckova O; Wibrand F; Andorsdóttir G; Joensen F; Sedlak D; Bleyer AJ; Kmoch S; Lyonnet S; Zikanova M
Hum Mol Genet; 2019 Nov; 28(22):3805-3814. PubMed ID: 31600779
[TBL] [Abstract][Full Text] [Related]
2. Genetic and metabolomic analysis of AdeD and AdeI mutants of de novo purine biosynthesis: cellular models of de novo purine biosynthesis deficiency disorders.
Duval N; Luhrs K; Wilkinson TG; Baresova V; Skopova V; Kmoch S; Vacano GN; Zikanova M; Patterson D
Mol Genet Metab; 2013 Mar; 108(3):178-189. PubMed ID: 23394948
[TBL] [Abstract][Full Text] [Related]
3. Octameric structure of the human bifunctional enzyme PAICS in purine biosynthesis.
Li SX; Tong YP; Xie XC; Wang QH; Zhou HN; Han Y; Zhang ZY; Gao W; Li SG; Zhang XC; Bi RC
J Mol Biol; 2007 Mar; 366(5):1603-14. PubMed ID: 17224163
[TBL] [Abstract][Full Text] [Related]
4. Zebrafish mutations in gart and paics identify crucial roles for de novo purine synthesis in vertebrate pigmentation and ocular development.
Ng A; Uribe RA; Yieh L; Nuckels R; Gross JM
Development; 2009 Aug; 136(15):2601-11. PubMed ID: 19570845
[TBL] [Abstract][Full Text] [Related]
5. Mutations of ATIC and ADSL affect purinosome assembly in cultured skin fibroblasts from patients with AICA-ribosiduria and ADSL deficiency.
Baresova V; Skopova V; Sikora J; Patterson D; Sovova J; Zikanova M; Kmoch S
Hum Mol Genet; 2012 Apr; 21(7):1534-43. PubMed ID: 22180458
[TBL] [Abstract][Full Text] [Related]
6. Role and regulation of coordinately expressed de novo purine biosynthetic enzymes PPAT and PAICS in lung cancer.
Goswami MT; Chen G; Chakravarthi BV; Pathi SS; Anand SK; Carskadon SL; Giordano TJ; Chinnaiyan AM; Thomas DG; Palanisamy N; Beer DG; Varambally S
Oncotarget; 2015 Sep; 6(27):23445-61. PubMed ID: 26140362
[TBL] [Abstract][Full Text] [Related]
7. Multienzyme interactions of the de novo purine biosynthetic protein PAICS facilitate purinosome formation and metabolic channeling.
He J; Zou LN; Pareek V; Benkovic SJ
J Biol Chem; 2022 May; 298(5):101853. PubMed ID: 35331738
[TBL] [Abstract][Full Text] [Related]
8. The Drosophila melanogaster ade5 gene encodes a bifunctional enzyme for two steps in the de novo purine synthesis pathway.
O'Donnell AF; Tiong S; Nash D; Clark DV
Genetics; 2000 Mar; 154(3):1239-53. PubMed ID: 10757766
[TBL] [Abstract][Full Text] [Related]
9. Mapping of the bovine genes of the de novo AMP synthesis pathway.
Bønsdorff T; Gautier M; Farstad W; Rønningen K; Lingaas F; Olsaker I
Anim Genet; 2004 Dec; 35(6):438-44. PubMed ID: 15566465
[TBL] [Abstract][Full Text] [Related]
10. Disorders of purine biosynthesis metabolism.
Dewulf JP; Marie S; Nassogne MC
Mol Genet Metab; 2022 Jul; 136(3):190-198. PubMed ID: 34998670
[TBL] [Abstract][Full Text] [Related]
11. Expression and Role of PAICS, a De Novo Purine Biosynthetic Gene in Prostate Cancer.
Chakravarthi BV; Goswami MT; Pathi SS; Dodson M; Chandrashekar DS; Agarwal S; Nepal S; Hodigere Balasubramanya SA; Siddiqui J; Lonigro RJ; Chinnaiyan AM; Kunju LP; Palanisamy N; Varambally S
Prostate; 2017 Jan; 77(1):10-21. PubMed ID: 27550065
[TBL] [Abstract][Full Text] [Related]
12. CRISPR-Cas9 induced mutations along de novo purine synthesis in HeLa cells result in accumulation of individual enzyme substrates and affect purinosome formation.
Baresova V; Krijt M; Skopova V; Souckova O; Kmoch S; Zikanova M
Mol Genet Metab; 2016 Nov; 119(3):270-277. PubMed ID: 27590927
[TBL] [Abstract][Full Text] [Related]
13. Crystal structures of human PAICS reveal substrate and product binding of an emerging cancer target.
Škerlová J; Unterlass J; Göttmann M; Marttila P; Homan E; Helleday T; Jemth AS; Stenmark P
J Biol Chem; 2020 Aug; 295(33):11656-11668. PubMed ID: 32571877
[TBL] [Abstract][Full Text] [Related]
14. A Role for De Novo Purine Metabolic Enzyme PAICS in Bladder Cancer Progression.
Chakravarthi BVSK; Rodriguez Pena MDC; Agarwal S; Chandrashekar DS; Hodigere Balasubramanya SA; Jabboure FJ; Matoso A; Bivalacqua TJ; Rezaei K; Chaux A; Grizzle WE; Sonpavde G; Gordetsky J; Netto GJ; Varambally S
Neoplasia; 2018 Sep; 20(9):894-904. PubMed ID: 30121007
[TBL] [Abstract][Full Text] [Related]
15. Crystal structure of the invertebrate bifunctional purine biosynthesis enzyme PAICS at 2.8 Å resolution.
Taschner M; Basquin J; Benda C; Lorentzen E
Proteins; 2013 Aug; 81(8):1473-8. PubMed ID: 23553965
[TBL] [Abstract][Full Text] [Related]
16. The CRISPR-Cas9 crATIC HeLa transcriptome: Characterization of a novel cellular model of ATIC deficiency and ZMP accumulation.
Mazzarino RC; Baresova V; Zikánová M; Duval N; Wilkinson TG; Patterson D; Vacano GN
Mol Genet Metab Rep; 2020 Dec; 25():100642. PubMed ID: 32939338
[TBL] [Abstract][Full Text] [Related]
17. Evidence Supporting Substrate Channeling between Domains of Human PAICS: A Time-Course Analysis of
Shon H; Matveeva EA; Jull EC; Hu Y; Coupet TA; Lee YS
Biochemistry; 2022 Apr; 61(7):575-582. PubMed ID: 35285625
[TBL] [Abstract][Full Text] [Related]
18. Carboxylases in de novo purine biosynthesis. Characterization of the Gallus gallus bifunctional enzyme.
Firestine SM; Davisson VJ
Biochemistry; 1994 Oct; 33(39):11917-26. PubMed ID: 7918410
[TBL] [Abstract][Full Text] [Related]
19. Metabolites of De Novo Purine Synthesis: Metabolic Regulators and Cytotoxic Compounds.
Souckova O; Skopova V; Baresova V; Sedlak D; Bleyer AJ; Kmoch S; Zikanova M
Metabolites; 2022 Dec; 12(12):. PubMed ID: 36557247
[TBL] [Abstract][Full Text] [Related]
20. Adenylosuccinate lyase deficiency.
Jurecka A; Zikanova M; Kmoch S; Tylki-Szymańska A
J Inherit Metab Dis; 2015 Mar; 38(2):231-42. PubMed ID: 25112391
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]