295 related articles for article (PubMed ID: 31604675)
1. Novel mRNA-Based Therapy Reduces Toxic Galactose Metabolites and Overcomes Galactose Sensitivity in a Mouse Model of Classic Galactosemia.
Balakrishnan B; An D; Nguyen V; DeAntonis C; Martini PGV; Lai K
Mol Ther; 2020 Jan; 28(1):304-312. PubMed ID: 31604675
[TBL] [Abstract][Full Text] [Related]
2. A galactose-1-phosphate uridylyltransferase-null rat model of classic galactosemia mimics relevant patient outcomes and reveals tissue-specific and longitudinal differences in galactose metabolism.
Rasmussen SA; Daenzer JMI; MacWilliams JA; Head ST; Williams MB; Geurts AM; Schroeder JP; Weinshenker D; Fridovich-Keil JL
J Inherit Metab Dis; 2020 May; 43(3):518-528. PubMed ID: 31845342
[TBL] [Abstract][Full Text] [Related]
3. Acute and long-term outcomes in a Drosophila melanogaster model of classic galactosemia occur independently of galactose-1-phosphate accumulation.
Daenzer JM; Jumbo-Lucioni PP; Hopson ML; Garza KR; Ryan EL; Fridovich-Keil JL
Dis Model Mech; 2016 Nov; 9(11):1375-1382. PubMed ID: 27562100
[TBL] [Abstract][Full Text] [Related]
4. Novel mRNA therapy restores GALT protein and enzyme activity in a zebrafish model of classic galactosemia.
Delnoy B; Haskovic M; Vanoevelen J; Steinbusch LKM; Vos EN; Knoops K; Zimmermann LJI; Noga M; Lefeber DJ; Martini PGV; Coelho AI; Rubio-Gozalbo ME
J Inherit Metab Dis; 2022 Jul; 45(4):748-758. PubMed ID: 35527402
[TBL] [Abstract][Full Text] [Related]
5. A pilot study of neonatal GALT gene replacement using AAV9 dramatically lowers galactose metabolites in blood, liver, and brain and minimizes cataracts in GALT-null rat pups.
Rasmussen SA; Daenzer JMI; Fridovich-Keil JL
J Inherit Metab Dis; 2021 Jan; 44(1):272-281. PubMed ID: 32882063
[TBL] [Abstract][Full Text] [Related]
6. Galactose 1-phosphate accumulates to high levels in galactose-treated cells due to low GALT activity and absence of product inhibition of GALK.
Oh SL; Cheng LY; J Zhou JF; Henke W; Hagen T
J Inherit Metab Dis; 2020 May; 43(3):529-539. PubMed ID: 31774565
[TBL] [Abstract][Full Text] [Related]
7. GALT deficiency causes UDP-hexose deficit in human galactosemic cells.
Lai K; Langley SD; Khwaja FW; Schmitt EW; Elsas LJ
Glycobiology; 2003 Apr; 13(4):285-94. PubMed ID: 12626383
[TBL] [Abstract][Full Text] [Related]
8. Involvement of endoplasmic reticulum stress in a novel Classic Galactosemia model.
Slepak TI; Tang M; Slepak VZ; Lai K
Mol Genet Metab; 2007; 92(1-2):78-87. PubMed ID: 17643331
[TBL] [Abstract][Full Text] [Related]
9. AAV-mediated expression of galactose-1-phosphate uridyltransferase corrects defects of galactose metabolism in classic galactosemia patient fibroblasts.
Brophy ML; Stansfield JC; Ahn Y; Cheng SH; Murphy JE; Bell RD
J Inherit Metab Dis; 2022 May; 45(3):481-492. PubMed ID: 34918784
[TBL] [Abstract][Full Text] [Related]
10. Effect of genotype on galactose-1-phosphate in classic galactosemia patients.
Yuzyuk T; Balakrishnan B; Schwarz EL; De Biase I; Hobert J; Longo N; Mao R; Lai K; Pasquali M
Mol Genet Metab; 2018 Nov; 125(3):258-265. PubMed ID: 30172461
[TBL] [Abstract][Full Text] [Related]
11. Subfertility and growth restriction in a new galactose-1 phosphate uridylyltransferase (GALT) - deficient mouse model.
Tang M; Siddiqi A; Witt B; Yuzyuk T; Johnson B; Fraser N; Chen W; Rascon R; Yin X; Goli H; Bodamer OA; Lai K
Eur J Hum Genet; 2014 Oct; 22(10):1172-9. PubMed ID: 24549051
[TBL] [Abstract][Full Text] [Related]
12. Galactose-1 phosphate uridylyltransferase (GalT) gene: A novel positive regulator of the PI3K/Akt signaling pathway in mouse fibroblasts.
Balakrishnan B; Chen W; Tang M; Huang X; Cakici DD; Siddiqi A; Berry G; Lai K
Biochem Biophys Res Commun; 2016 Jan; 470(1):205-212. PubMed ID: 26773505
[TBL] [Abstract][Full Text] [Related]
13. Galactosemia: when is it a newborn screening emergency?
Berry GT
Mol Genet Metab; 2012 May; 106(1):7-11. PubMed ID: 22483615
[TBL] [Abstract][Full Text] [Related]
14. Genetic and functional studies reveal a novel noncoding variant in GALT associated with a false positive newborn screening result for galactosemia.
Liu Y; Sidhu A; Bean LH; Conway RL; Fridovich-Keil JL
Clin Chim Acta; 2015 Jun; 446():171-4. PubMed ID: 25920691
[TBL] [Abstract][Full Text] [Related]
15. Galactose metabolism in mice with galactose-1-phosphate uridyltransferase deficiency: sucklings and 7-week-old animals fed a high-galactose diet.
Ning C; Reynolds R; Chen J; Yager C; Berry GT; Leslie N; Segal S
Mol Genet Metab; 2001 Apr; 72(4):306-15. PubMed ID: 11286504
[TBL] [Abstract][Full Text] [Related]
16. Neonatal GALT gene replacement offers metabolic and phenotypic correction through early adulthood in a rat model of classic galactosemia.
Daenzer JMI; Rasmussen SA; Patel S; McKenna J; Fridovich-Keil JL
J Inherit Metab Dis; 2022 Mar; 45(2):203-214. PubMed ID: 34964137
[TBL] [Abstract][Full Text] [Related]
17. A Drosophila melanogaster model of classic galactosemia.
Kushner RF; Ryan EL; Sefton JM; Sanders RD; Lucioni PJ; Moberg KH; Fridovich-Keil JL
Dis Model Mech; 2010; 3(9-10):618-27. PubMed ID: 20519569
[TBL] [Abstract][Full Text] [Related]
18. Distinct roles of galactose-1P in galactose-mediated growth arrest of yeast deficient in galactose-1P uridylyltransferase (GALT) and UDP-galactose 4'-epimerase (GALE).
Mumma JO; Chhay JS; Ross KL; Eaton JS; Newell-Litwa KA; Fridovich-Keil JL
Mol Genet Metab; 2008 Feb; 93(2):160-71. PubMed ID: 17981065
[TBL] [Abstract][Full Text] [Related]
19. The ability of an LC-MS/MS-based erythrocyte GALT enzyme assay to predict the phenotype in subjects with GALT deficiency.
Demirbas D; Huang X; Daesety V; Feenstra S; Haskovic M; Qi W; Gubbels CS; Hecht L; Levy HL; Waisbren SE; Berry GT
Mol Genet Metab; 2019 Apr; 126(4):368-376. PubMed ID: 30718057
[TBL] [Abstract][Full Text] [Related]
20. Reversal of aberrant PI3K/Akt signaling by Salubrinal in a GalT-deficient mouse model.
Balakrishnan B; Nicholas C; Siddiqi A; Chen W; Bales E; Feng M; Johnson J; Lai K
Biochim Biophys Acta Mol Basis Dis; 2017 Dec; 1863(12):3286-3293. PubMed ID: 28844959
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]