124 related articles for article (PubMed ID: 31605927)
1. Adapalene inhibits ovarian cancer ES-2 cells growth by targeting glutamic-oxaloacetic transaminase 1.
Wang Q; Zhang Q; Luan S; Yang K; Zheng M; Li K; Chen L; Li H
Bioorg Chem; 2019 Dec; 93():103315. PubMed ID: 31605927
[TBL] [Abstract][Full Text] [Related]
2. Biochemical Characterization and Structure-Based Mutational Analysis Provide Insight into the Binding and Mechanism of Action of Novel Aspartate Aminotransferase Inhibitors.
Holt MC; Assar Z; Beheshti Zavareh R; Lin L; Anglin J; Mashadova O; Haldar D; Mullarky E; Kremer DM; Cantley LC; Kimmelman AC; Stein AJ; Lairson LL; Lyssiotis CA
Biochemistry; 2018 Nov; 57(47):6604-6614. PubMed ID: 30365304
[TBL] [Abstract][Full Text] [Related]
3. Inhibition of glutamate oxaloacetate transaminase 1 in cancer cell lines results in altered metabolism with increased dependency of glucose.
Zhou X; Curbo S; Li F; Krishnan S; Karlsson A
BMC Cancer; 2018 May; 18(1):559. PubMed ID: 29751795
[TBL] [Abstract][Full Text] [Related]
4. Glutamic oxaloacetic transaminase 1 as a potential target in human cancer.
Song Z; Yang Y; Wu Y; Zheng M; Sun D; Li H; Chen L
Eur J Pharmacol; 2022 Feb; 917():174754. PubMed ID: 35007521
[TBL] [Abstract][Full Text] [Related]
5. Aspulvinone O, a natural inhibitor of GOT1 suppresses pancreatic ductal adenocarcinoma cells growth by interfering glutamine metabolism.
Sun W; Luan S; Qi C; Tong Q; Yan S; Li H; Zhang Y
Cell Commun Signal; 2019 Aug; 17(1):111. PubMed ID: 31470862
[TBL] [Abstract][Full Text] [Related]
6. A covalent small molecule inhibitor of glutamate-oxaloacetate transaminase 1 impairs pancreatic cancer growth.
Yoshida T; Yamasaki S; Kaneko O; Taoka N; Tomimoto Y; Namatame I; Yahata T; Kuromitsu S; Cantley LC; Lyssiotis CA
Biochem Biophys Res Commun; 2020 Feb; 522(3):633-638. PubMed ID: 31787239
[TBL] [Abstract][Full Text] [Related]
7. Inhibition of GOT1 sensitizes colorectal cancer cells to 5-fluorouracil.
Hong C; Zheng J; Li X
Cancer Chemother Pharmacol; 2017 Apr; 79(4):835-840. PubMed ID: 28314989
[TBL] [Abstract][Full Text] [Related]
8. miR-9 regulates ferroptosis by targeting glutamic-oxaloacetic transaminase GOT1 in melanoma.
Zhang K; Wu L; Zhang P; Luo M; Du J; Gao T; O'Connell D; Wang G; Wang H; Yang Y
Mol Carcinog; 2018 Nov; 57(11):1566-1576. PubMed ID: 30035324
[TBL] [Abstract][Full Text] [Related]
9. The discovery of a non-competitive GOT1 inhibitor, hydralazine hydrochloride, via a coupling reaction-based high-throughput screening assay.
Wu Q; Sun Z; Chen Z; Liu J; Ding H; Luo C; Wang M; Du D
Bioorg Med Chem Lett; 2022 Oct; 73():128883. PubMed ID: 35820623
[TBL] [Abstract][Full Text] [Related]
10. miR-9-5p inhibits pancreatic cancer cell proliferation, invasion and glutamine metabolism by targeting GOT1.
Wang J; Wang B; Ren H; Chen W
Biochem Biophys Res Commun; 2019 Jan; 509(1):241-248. PubMed ID: 30591220
[TBL] [Abstract][Full Text] [Related]
11. Discovery of GOT1 Inhibitors from a Marine-Derived
Yan S; Qi C; Song W; Xu Q; Gu L; Sun W; Zhang Y
Mar Drugs; 2021 Oct; 19(11):. PubMed ID: 34822459
[TBL] [Abstract][Full Text] [Related]
12. GOT1 inhibition promotes pancreatic cancer cell death by ferroptosis.
Kremer DM; Nelson BS; Lin L; Yarosz EL; Halbrook CJ; Kerk SA; Sajjakulnukit P; Myers A; Thurston G; Hou SW; Carpenter ES; Andren AC; Nwosu ZC; Cusmano N; Wisner S; Mbah NE; Shan M; Das NK; Magnuson B; Little AC; Savani MR; Ramos J; Gao T; Sastra SA; Palermo CF; Badgley MA; Zhang L; Asara JM; McBrayer SK; di Magliano MP; Crawford HC; Shah YM; Olive KP; Lyssiotis CA
Nat Commun; 2021 Aug; 12(1):4860. PubMed ID: 34381026
[TBL] [Abstract][Full Text] [Related]
13. Ziprasidone suppresses pancreatic adenocarcinoma cell proliferation by targeting GOT1 to trigger glutamine metabolism reprogramming.
Yang Y; Zheng M; Han F; Shang L; Li M; Gu X; Li H; Chen L
J Mol Med (Berl); 2022 Apr; 100(4):599-612. PubMed ID: 35212782
[TBL] [Abstract][Full Text] [Related]
14. GOT1-mediated anaplerotic glutamine metabolism regulates chronic acidosis stress in pancreatic cancer cells.
Abrego J; Gunda V; Vernucci E; Shukla SK; King RJ; Dasgupta A; Goode G; Murthy D; Yu F; Singh PK
Cancer Lett; 2017 Aug; 400():37-46. PubMed ID: 28455244
[TBL] [Abstract][Full Text] [Related]
15. Inhibition of endogenous blood glutamate oxaloacetate transaminase enhances the ischemic damage.
Dopico-López A; Pérez-Mato M; da Silva-Candal A; Iglesias-Rey R; Rabinkov A; Bugallo-Casal A; Sobrino T; Mirelman D; Castillo J; Campos F
Transl Res; 2021 Apr; 230():68-81. PubMed ID: 33132087
[TBL] [Abstract][Full Text] [Related]
16. Expression, purification and preliminary crystallographic studies of human glutamate oxaloacetate transaminase 1 (GOT1).
Jiang X; Chang H; Zhou Y
Protein Expr Purif; 2015 Sep; 113():102-6. PubMed ID: 26003525
[TBL] [Abstract][Full Text] [Related]
17. Targeting AR-positive breast cancer cells via drug repurposing approach.
Dutta P; Sen P; Kandasamy T; Ghosh SS
Comput Biol Chem; 2024 Feb; 108():108007. PubMed ID: 38157661
[TBL] [Abstract][Full Text] [Related]
18. Glutamate-Oxaloacetate Transaminase 1 Impairs Glycolysis by Interacting with Pyruvate Carboxylase and Further Inhibits the Malignant Phenotypes of Glioblastoma Cells.
Tang T; Liu Y; Yang M; Tu M; Zhu W; Chen M
World Neurosurg; 2021 Oct; 154():e616-e626. PubMed ID: 34325031
[TBL] [Abstract][Full Text] [Related]
19. HIF-2α regulates non-canonical glutamine metabolism via activation of PI3K/mTORC2 pathway in human pancreatic ductal adenocarcinoma.
Li W; Chen C; Zhao X; Ye H; Zhao Y; Fu Z; Pan W; Zheng S; Wei L; Nong T; Li Z; Chen R
J Cell Mol Med; 2017 Nov; 21(11):2896-2908. PubMed ID: 28544376
[TBL] [Abstract][Full Text] [Related]
20. c-Myc protects hepatocellular carcinoma cell from ferroptosis induced by glutamine deprivation via upregulating GOT1 and Nrf2.
Zhao Y; Wang Y; Miao Z; Liu Y; Yang Q
Mol Biol Rep; 2023 Aug; 50(8):6627-6641. PubMed ID: 37358765
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
