378 related articles for article (PubMed ID: 31607539)
1. dCas9-Based Scn1a Gene Activation Restores Inhibitory Interneuron Excitability and Attenuates Seizures in Dravet Syndrome Mice.
Colasante G; Lignani G; Brusco S; Di Berardino C; Carpenter J; Giannelli S; Valassina N; Bido S; Ricci R; Castoldi V; Marenna S; Church T; Massimino L; Morabito G; Benfenati F; Schorge S; Leocani L; Kullmann DM; Broccoli V
Mol Ther; 2020 Jan; 28(1):235-253. PubMed ID: 31607539
[TBL] [Abstract][Full Text] [Related]
2. CRISPR/dCas9-based Scn1a gene activation in inhibitory neurons ameliorates epileptic and behavioral phenotypes of Dravet syndrome model mice.
Yamagata T; Raveau M; Kobayashi K; Miyamoto H; Tatsukawa T; Ogiwara I; Itohara S; Hensch TK; Yamakawa K
Neurobiol Dis; 2020 Jul; 141():104954. PubMed ID: 32445790
[TBL] [Abstract][Full Text] [Related]
3. Targeted Augmentation of Nuclear Gene Output (TANGO) of Scn1a rescues parvalbumin interneuron excitability and reduces seizures in a mouse model of Dravet Syndrome.
Wengert ER; Wagley PK; Strohm SM; Reza N; Wenker IC; Gaykema RP; Christiansen A; Liau G; Patel MK
Brain Res; 2022 Jan; 1775():147743. PubMed ID: 34843701
[TBL] [Abstract][Full Text] [Related]
4. Impairment of Sharp-Wave Ripples in a Murine Model of Dravet Syndrome.
Cheah CS; Lundstrom BN; Catterall WA; Oakley JC
J Neurosci; 2019 Nov; 39(46):9251-9260. PubMed ID: 31537705
[TBL] [Abstract][Full Text] [Related]
5. Sexually Divergent Mortality and Partial Phenotypic Rescue After Gene Therapy in a Mouse Model of Dravet Syndrome.
Niibori Y; Lee SJ; Minassian BA; Hampson DR
Hum Gene Ther; 2020 Mar; 31(5-6):339-351. PubMed ID: 31830809
[TBL] [Abstract][Full Text] [Related]
6. Cell-Selective Adeno-Associated Virus-Mediated
Tanenhaus A; Stowe T; Young A; McLaughlin J; Aeran R; Lin IW; Li J; Hosur R; Chen M; Leedy J; Chou T; Pillay S; Vila MC; Kearney JA; Moorhead M; Belle A; Tagliatela S
Hum Gene Ther; 2022 Jun; 33(11-12):579-597. PubMed ID: 35435735
[TBL] [Abstract][Full Text] [Related]
7. Scn1a gene reactivation after symptom onset rescues pathological phenotypes in a mouse model of Dravet syndrome.
Valassina N; Brusco S; Salamone A; Serra L; Luoni M; Giannelli S; Bido S; Massimino L; Ungaro F; Mazzara PG; D'Adamo P; Lignani G; Broccoli V; Colasante G
Nat Commun; 2022 Jan; 13(1):161. PubMed ID: 35013317
[TBL] [Abstract][Full Text] [Related]
8. A Transient Developmental Window of Fast-Spiking Interneuron Dysfunction in a Mouse Model of Dravet Syndrome.
Favero M; Sotuyo NP; Lopez E; Kearney JA; Goldberg EM
J Neurosci; 2018 Sep; 38(36):7912-7927. PubMed ID: 30104343
[TBL] [Abstract][Full Text] [Related]
9. A selective Na
Chow CY; Chin YKY; Ma L; Undheim EAB; Herzig V; King GF
Biochem Pharmacol; 2020 Nov; 181():113991. PubMed ID: 32335140
[TBL] [Abstract][Full Text] [Related]
10. Genetic background modulates impaired excitability of inhibitory neurons in a mouse model of Dravet syndrome.
Rubinstein M; Westenbroek RE; Yu FH; Jones CJ; Scheuer T; Catterall WA
Neurobiol Dis; 2015 Jan; 73():106-17. PubMed ID: 25281316
[TBL] [Abstract][Full Text] [Related]
11. Preictal dysfunctions of inhibitory interneurons paradoxically lead to their rebound hyperactivity and to low-voltage-fast onset seizures in Dravet syndrome.
Capitano F; Kuchenbuch M; Lavigne J; Chaptoukaev H; Zuluaga MA; Lorenzi M; Nabbout R; Mantegazza M
Proc Natl Acad Sci U S A; 2024 Jun; 121(23):e2316364121. PubMed ID: 38809712
[TBL] [Abstract][Full Text] [Related]
12. Electrophysiological Alterations of Pyramidal Cells and Interneurons of the CA1 Region of the Hippocampus in a Novel Mouse Model of Dravet Syndrome.
Dyment DA; Schock SC; Deloughery K; Tran MH; Ure K; Nutter LMJ; Creighton A; Yuan J; Banderali U; Comas T; Baumann E; Jezierski A; ; Boycott KM; Mackenzie AE; Martina M
Genetics; 2020 Aug; 215(4):1055-1066. PubMed ID: 32554600
[TBL] [Abstract][Full Text] [Related]
13. Knock-in model of Dravet syndrome reveals a constitutive and conditional reduction in sodium current.
Schutte RJ; Schutte SS; Algara J; Barragan EV; Gilligan J; Staber C; Savva YA; Smith MA; Reenan R; O'Dowd DK
J Neurophysiol; 2014 Aug; 112(4):903-12. PubMed ID: 24805083
[TBL] [Abstract][Full Text] [Related]
14. Preferential expression of SCN1A in GABAergic neurons improves survival and epileptic phenotype in a mouse model of Dravet syndrome.
Ricobaraza A; Bunuales M; Gonzalez-Aparicio M; Fadila S; Rubinstein M; Vides-Urrestarazu I; Banderas J; Sola-Sevilla N; Sanchez-Carpintero R; Lanciego JL; Roda E; Honrubia A; Arnaiz P; Hernandez-Alcoceba R
J Mol Med (Berl); 2023 Dec; 101(12):1587-1601. PubMed ID: 37819378
[TBL] [Abstract][Full Text] [Related]
15. Vasoactive intestinal peptide-expressing interneurons are impaired in a mouse model of Dravet syndrome.
Goff KM; Goldberg EM
Elife; 2019 Jul; 8():. PubMed ID: 31282864
[TBL] [Abstract][Full Text] [Related]
16. Preferential inactivation of Scn1a in parvalbumin interneurons increases seizure susceptibility.
Dutton SB; Makinson CD; Papale LA; Shankar A; Balakrishnan B; Nakazawa K; Escayg A
Neurobiol Dis; 2013 Jan; 49():211-20. PubMed ID: 22926190
[TBL] [Abstract][Full Text] [Related]
17. Dravet Syndrome: A Developmental and Epileptic Encephalopathy.
Lopez-Santiago L; Isom LL
Epilepsy Curr; 2019 Jan; 19(1):51-53. PubMed ID: 30838929
[TBL] [Abstract][Full Text] [Related]
18. Impaired excitability of somatostatin- and parvalbumin-expressing cortical interneurons in a mouse model of Dravet syndrome.
Tai C; Abe Y; Westenbroek RE; Scheuer T; Catterall WA
Proc Natl Acad Sci U S A; 2014 Jul; 111(30):E3139-48. PubMed ID: 25024183
[TBL] [Abstract][Full Text] [Related]
19. Strain- and age-dependent hippocampal neuron sodium currents correlate with epilepsy severity in Dravet syndrome mice.
Mistry AM; Thompson CH; Miller AR; Vanoye CG; George AL; Kearney JA
Neurobiol Dis; 2014 May; 65():1-11. PubMed ID: 24434335
[TBL] [Abstract][Full Text] [Related]
20. A novel rat model of Dravet syndrome recapitulates clinical hallmarks.
Li M; Yang L; Qian W; Ray S; Lu Z; Liu T; Zou YY; Naumann RK; Wang H
Neurobiol Dis; 2023 Aug; 184():106193. PubMed ID: 37295561
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
