These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

195 related articles for article (PubMed ID: 31611414)

  • 1. A tetrapeptide class of biased analgesics from an Australian fungus targets the µ-opioid receptor.
    Dekan Z; Sianati S; Yousuf A; Sutcliffe KJ; Gillis A; Mallet C; Singh P; Jin AH; Wang AM; Mohammadi SA; Stewart M; Ratnayake R; Fontaine F; Lacey E; Piggott AM; Du YP; Canals M; Sessions RB; Kelly E; Capon RJ; Alewood PF; Christie MJ
    Proc Natl Acad Sci U S A; 2019 Oct; 116(44):22353-22358. PubMed ID: 31611414
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Endomorphin-2: a biased agonist at the μ-opioid receptor.
    Rivero G; Llorente J; McPherson J; Cooke A; Mundell SJ; McArdle CA; Rosethorne EM; Charlton SJ; Krasel C; Bailey CP; Henderson G; Kelly E
    Mol Pharmacol; 2012 Aug; 82(2):178-88. PubMed ID: 22553358
    [TBL] [Abstract][Full Text] [Related]  

  • 3. μ-opioid receptors: correlation of agonist efficacy for signalling with ability to activate internalization.
    McPherson J; Rivero G; Baptist M; Llorente J; Al-Sabah S; Krasel C; Dewey WL; Bailey CP; Rosethorne EM; Charlton SJ; Henderson G; Kelly E
    Mol Pharmacol; 2010 Oct; 78(4):756-66. PubMed ID: 20647394
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Agonist Binding and Desensitization of the μ-Opioid Receptor Is Modulated by Phosphorylation of the C-Terminal Tail Domain.
    Birdsong WT; Arttamangkul S; Bunzow JR; Williams JT
    Mol Pharmacol; 2015 Oct; 88(4):816-24. PubMed ID: 25934731
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Redoubling the ring size of an endomorphin-2 analog transforms a centrally acting mu-opioid receptor agonist into a pure peripheral analgesic.
    Piekielna J; De Marco R; Gentilucci L; Cerlesi MC; Calo' G; Tömböly C; Artali R; Janecka A
    Biopolymers; 2016 May; 106(3):309-17. PubMed ID: 27038094
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Endomorphin-1 and endomorphin-2 are partial agonists at the human mu-opioid receptor.
    Hosohata K; Burkey TH; Alfaro-Lopez J; Varga E; Hruby VJ; Roeske WR; Yamamura HI
    Eur J Pharmacol; 1998 Apr; 346(1):111-4. PubMed ID: 9617760
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Biased agonism of clinically approved μ-opioid receptor agonists and TRV130 is not controlled by binding and signaling kinetics.
    Pedersen MF; Wróbel TM; Märcher-Rørsted E; Pedersen DS; Møller TC; Gabriele F; Pedersen H; Matosiuk D; Foster SR; Bouvier M; Bräuner-Osborne H
    Neuropharmacology; 2020 Apr; 166():107718. PubMed ID: 31351108
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Residues W320 and Y328 within the binding site of the μ-opioid receptor influence opiate ligand bias.
    Hothersall JD; Torella R; Humphreys S; Hooley M; Brown A; McMurray G; Nickolls SA
    Neuropharmacology; 2017 May; 118():46-58. PubMed ID: 28283391
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Carfentanil is a β-arrestin-biased agonist at the μ opioid receptor.
    Ramos-Gonzalez N; Groom S; Sutcliffe KJ; Bancroft S; Bailey CP; Sessions RB; Henderson G; Kelly E
    Br J Pharmacol; 2023 Sep; 180(18):2341-2360. PubMed ID: 37005796
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Noribogaine is a G-protein biased κ-opioid receptor agonist.
    Maillet EL; Milon N; Heghinian MD; Fishback J; Schürer SC; Garamszegi N; Mash DC
    Neuropharmacology; 2015 Dec; 99():675-88. PubMed ID: 26302653
    [TBL] [Abstract][Full Text] [Related]  

  • 11. An opioid agonist that does not induce mu-opioid receptor--arrestin interactions or receptor internalization.
    Groer CE; Tidgewell K; Moyer RA; Harding WW; Rothman RB; Prisinzano TE; Bohn LM
    Mol Pharmacol; 2007 Feb; 71(2):549-57. PubMed ID: 17090705
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Mu Opioids Induce Biased Signaling at the Full-Length Seven Transmembrane C-Terminal Splice Variants of the mu Opioid Receptor Gene, Oprm1.
    Narayan A; Hunkele A; Xu J; Bassoni DL; Pasternak GW; Pan YX
    Cell Mol Neurobiol; 2021 Jul; 41(5):1059-1074. PubMed ID: 33033993
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Comparison of the antinociceptive and antirewarding profiles of novel bifunctional nociceptin receptor/mu-opioid receptor ligands: implications for therapeutic applications.
    Toll L; Khroyan TV; Polgar WE; Jiang F; Olsen C; Zaveri NT
    J Pharmacol Exp Ther; 2009 Dec; 331(3):954-64. PubMed ID: 19773529
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Critical Assessment of G Protein-Biased Agonism at the μ-Opioid Receptor.
    Gillis A; Kliewer A; Kelly E; Henderson G; Christie MJ; Schulz S; Canals M
    Trends Pharmacol Sci; 2020 Dec; 41(12):947-959. PubMed ID: 33097283
    [TBL] [Abstract][Full Text] [Related]  

  • 15. A bifunctional-biased mu-opioid agonist-neuropeptide FF receptor antagonist as analgesic with improved acute and chronic side effects.
    Drieu la Rochelle A; Guillemyn K; Dumitrascuta M; Martin C; Utard V; Quillet R; Schneider S; Daubeuf F; Willemse T; Mampuys P; Maes BUW; Frossard N; Bihel F; Spetea M; Simonin F; Ballet S
    Pain; 2018 Sep; 159(9):1705-1718. PubMed ID: 29708942
    [TBL] [Abstract][Full Text] [Related]  

  • 16. TRV0109101, a G Protein-Biased Agonist of the
    Koblish M; Carr R; Siuda ER; Rominger DH; Gowen-MacDonald W; Cowan CL; Crombie AL; Violin JD; Lark MW
    J Pharmacol Exp Ther; 2017 Aug; 362(2):254-262. PubMed ID: 28533287
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Intracerebroventricular administration of CYX-6, a potent μ-opioid receptor agonist, a δ- and κ-opioid receptor antagonist and a biased ligand at μ, δ & κ-opioid receptors, evokes antinociception with minimal constipation and respiratory depression in rats in contrast to morphine.
    Imam MZ; Kuo A; Ghassabian S; Cai Y; Qin Y; Li T; Smith MT
    Eur J Pharmacol; 2020 Mar; 871():172918. PubMed ID: 31958457
    [TBL] [Abstract][Full Text] [Related]  

  • 18. In vitro and in vivo activity of cyclopeptide Dmt-c[d-Lys-Phe-Asp]NH
    Gach-Janczak K; Piekielna-Ciesielska J; Adamska-Bartłomiejczyk A; Wtorek K; Ferrari F; Calo' G; Szymaszkiewicz A; Piasecka-Zelga J; Janecka A
    Peptides; 2018 Jul; 105():51-57. PubMed ID: 29684591
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Molecular insights into the biased signaling mechanism of the μ-opioid receptor.
    Cong X; Maurel D; Déméné H; Vasiliauskaité-Brooks I; Hagelberger J; Peysson F; Saint-Paul J; Golebiowski J; Granier S; Sounier R
    Mol Cell; 2021 Oct; 81(20):4165-4175.e6. PubMed ID: 34433090
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Tetrapeptide Endomorphin Analogs Require Both Full Length and Truncated Splice Variants of the Mu Opioid Receptor Gene Oprm1 for Analgesia.
    Marrone GF; Lu Z; Rossi G; Narayan A; Hunkele A; Marx S; Xu J; Pintar J; Majumdar S; Pan YX; Pasternak GW
    ACS Chem Neurosci; 2016 Dec; 7(12):1717-1727. PubMed ID: 27648914
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.