BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

174 related articles for article (PubMed ID: 31614718)

  • 1. The LQB-223 Compound Modulates Antiapoptotic Proteins and Impairs Breast Cancer Cell Growth and Migration.
    Lemos LGT; Longo GMDC; Mendonça BDS; Robaina MC; Brum MCM; Cirilo CA; Gimba ERP; Costa PRR; Buarque CD; Nestal de Moraes G; Maia RC
    Int J Mol Sci; 2019 Oct; 20(20):. PubMed ID: 31614718
    [TBL] [Abstract][Full Text] [Related]  

  • 2. 11a-N-Tosyl-5-deoxi-pterocarpan, LQB-223, a novel compound with potent antineoplastic activity toward breast cancer cells with different phenotypes.
    Lemos LG; Nestal de Moraes G; Delbue D; Vasconcelos Fda C; Bernardo PS; Lam EW; Buarque CD; Costa PR; Maia RC
    J Cancer Res Clin Oncol; 2016 Oct; 142(10):2119-30. PubMed ID: 27520309
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The therapeutical potential of a novel pterocarpanquinone LQB-118 to target inhibitor of apoptosis proteins in acute myeloid leukemia cells.
    de Souza Reis FR; de Faria FC; Castro CP; de Souza PS; da Cunha Vasconcelos F; Bello RD; da Silva AJ; Costa PR; Maia RC
    Anticancer Agents Med Chem; 2013 Feb; 13(2):341-51. PubMed ID: 22721384
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Doxorubicin induces cell death in breast cancer cells regardless of Survivin and XIAP expression levels.
    Nestal de Moraes G; Vasconcelos FC; Delbue D; Mognol GP; Sternberg C; Viola JP; Maia RC
    Eur J Cell Biol; 2013; 92(8-9):247-56. PubMed ID: 24064045
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Insights into the Biological Evaluation of Pterocarpanquinones and Carbapterocarpans with Anti-tumor Activity against MDR Leukemias.
    Rumjanek VM; Maia RC; Salustiano EJ; Costa PRR
    Anticancer Agents Med Chem; 2019; 19(1):29-37. PubMed ID: 29692266
    [TBL] [Abstract][Full Text] [Related]  

  • 6. LQB-118, a pterocarpanquinone structurally related to lapachol [2-hydroxy-3-(3-methyl-2-butenyl)-1,4-naphthoquinone]: a novel class of agent with high apoptotic effect in chronic myeloid leukemia cells.
    Maia RC; Vasconcelos FC; de Sá Bacelar T; Salustiano EJ; da Silva LF; Pereira DL; Moellman-Coelho A; Netto CD; da Silva AJ; Rumjanek VM; Costa PR
    Invest New Drugs; 2011 Dec; 29(6):1143-55. PubMed ID: 20499132
    [TBL] [Abstract][Full Text] [Related]  

  • 7. FOXM1 targets XIAP and Survivin to modulate breast cancer survival and chemoresistance.
    Nestal de Moraes G; Delbue D; Silva KL; Robaina MC; Khongkow P; Gomes AR; Zona S; Crocamo S; Mencalha AL; Magalhães LM; Lam EW; Maia RC
    Cell Signal; 2015 Dec; 27(12):2496-505. PubMed ID: 26404623
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The pterocarpanquinone LQB-118 inhibits tumor cell proliferation by downregulation of c-Myc and cyclins D1 and B1 mRNA and upregulation of p21 cell cycle inhibitor expression.
    Martino T; Magalhães FC; Justo GA; Coelho MG; Netto CD; Costa PR; Sabino KC
    Bioorg Med Chem; 2014 Jun; 22(12):3115-22. PubMed ID: 24794748
    [TBL] [Abstract][Full Text] [Related]  

  • 9. 11a-N-Tosyl-5-deoxi-pterocarpan (LQB-223), a promising prototype for targeting MDR leukemia cell lines.
    Buarque CD; Salustiano EJ; Fraga KC; Alves BR; Costa PR
    Eur J Med Chem; 2014 May; 78():190-7. PubMed ID: 24681983
    [TBL] [Abstract][Full Text] [Related]  

  • 10. MiR-205 and miR-218 expression is associated with carboplatin chemoresistance and regulation of apoptosis via Mcl-1 and Survivin in lung cancer cells.
    Zarogoulidis P; Petanidis S; Kioseoglou E; Domvri K; Anestakis D; Zarogoulidis K
    Cell Signal; 2015 Aug; 27(8):1576-88. PubMed ID: 25917317
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Effects of α-Mangostin on Viability, Growth and Cohesion of Multicellular Spheroids Derived from Human Breast Cancer Cell Lines.
    Scolamiero G; Pazzini C; Bonafè F; Guarnieri C; Muscari C
    Int J Med Sci; 2018; 15(1):23-30. PubMed ID: 29333084
    [No Abstract]   [Full Text] [Related]  

  • 12. Undecylprodigiosin selectively induces apoptosis in human breast carcinoma cells independent of p53.
    Ho TF; Ma CJ; Lu CH; Tsai YT; Wei YH; Chang JS; Lai JK; Cheuh PJ; Yeh CT; Tang PC; Tsai Chang J; Ko JL; Liu FS; Yen HE; Chang CC
    Toxicol Appl Pharmacol; 2007 Dec; 225(3):318-28. PubMed ID: 17881028
    [TBL] [Abstract][Full Text] [Related]  

  • 13. CDK4 inhibition and doxorubicin mediate breast cancer cell apoptosis through Smad3 and survivin.
    Tarasewicz E; Hamdan R; Straehla J; Hardy A; Nunez O; Zelivianski S; Dokic D; Jeruss JS
    Cancer Biol Ther; 2014 Oct; 15(10):1301-11. PubMed ID: 25006666
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The orally active pterocarpanquinone LQB-118 exhibits cytotoxicity in prostate cancer cell and tumor models through cellular redox stress.
    Martino T; Kudrolli TA; Kumar B; Salviano I; Mencalha A; Coelho MGP; Justo G; Costa PRR; Sabino KCC; Lupold SE
    Prostate; 2018 Feb; 78(2):140-151. PubMed ID: 29105806
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Chemo-sensitivity of Two-dimensional Monolayer and Three-dimensional Spheroid of Breast Cancer MCF-7 Cells to Daunorubicin, Docetaxel, and Arsenic Disulfide.
    Uematsu N; Zhao Y; Kiyomi A; Yuan BO; Onda K; Tanaka S; Sugiyama K; Sugiura M; Takagi N; Hayakawa A; Hirano T
    Anticancer Res; 2018 Apr; 38(4):2101-2108. PubMed ID: 29599328
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Iron-free and iron-saturated bovine lactoferrin inhibit survivin expression and differentially modulate apoptosis in breast cancer.
    Gibbons JA; Kanwar JR; Kanwar RK
    BMC Cancer; 2015 May; 15():425. PubMed ID: 25998617
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Interaction between bioactive compound 11a-N-tosyl-5-deoxi-pterocarpan (LQB-223) and Calf thymus DNA: Spectroscopic approach, electrophoresis and theoretical studies.
    Silva MM; Nascimento EOO; Silva EF; Araújo JX; Santana CC; Grillo LAM; de Oliveira RS; R R Costa P; Buarque CD; Santos JCC; Figueiredo IM
    Int J Biol Macromol; 2017 Mar; 96():223-233. PubMed ID: 27988296
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Gambogic acid sensitizes resistant breast cancer cells to doxorubicin through inhibiting P-glycoprotein and suppressing survivin expression.
    Wang S; Wang L; Chen M; Wang Y
    Chem Biol Interact; 2015 Jun; 235():76-84. PubMed ID: 25824409
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The pterocarpanquinone LQB 118 induces apoptosis in tumor cells through the intrinsic pathway and the endoplasmic reticulum stress pathway.
    de Sá Bacelar T; da Silva AJ; Costa PR; Rumjanek VM
    Anticancer Drugs; 2013 Jan; 24(1):73-83. PubMed ID: 22960938
    [TBL] [Abstract][Full Text] [Related]  

  • 20. MCL-1 inhibition provides a new way to suppress breast cancer metastasis and increase sensitivity to dasatinib.
    Young AI; Law AM; Castillo L; Chong S; Cullen HD; Koehler M; Herzog S; Brummer T; Lee EF; Fairlie WD; Lucas MC; Herrmann D; Allam A; Timpson P; Watkins DN; Millar EK; O'Toole SA; Gallego-Ortega D; Ormandy CJ; Oakes SR
    Breast Cancer Res; 2016 Dec; 18(1):125. PubMed ID: 27931239
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.