335 related articles for article (PubMed ID: 31614754)
21. NK314, a topoisomerase II inhibitor that specifically targets the alpha isoform.
Toyoda E; Kagaya S; Cowell IG; Kurosawa A; Kamoshita K; Nishikawa K; Iiizumi S; Koyama H; Austin CA; Adachi N
J Biol Chem; 2008 Aug; 283(35):23711-20. PubMed ID: 18596031
[TBL] [Abstract][Full Text] [Related]
22. Canonical non-homologous end-joining promotes genome mutagenesis and translocations induced by transcription-associated DNA topoisomerase 2 activity.
Olmedo-Pelayo J; Rubio-Contreras D; Gómez-Herreros F
Nucleic Acids Res; 2020 Sep; 48(16):9147-9160. PubMed ID: 32749454
[TBL] [Abstract][Full Text] [Related]
23. TDP2-dependent non-homologous end-joining protects against topoisomerase II-induced DNA breaks and genome instability in cells and in vivo.
Gómez-Herreros F; Romero-Granados R; Zeng Z; Alvarez-Quilón A; Quintero C; Ju L; Umans L; Vermeire L; Huylebroeck D; Caldecott KW; Cortés-Ledesma F
PLoS Genet; 2013; 9(3):e1003226. PubMed ID: 23505375
[TBL] [Abstract][Full Text] [Related]
24. Topoisomerase II-mediated DNA damage is differently repaired during the cell cycle by non-homologous end joining and homologous recombination.
de Campos-Nebel M; Larripa I; González-Cid M
PLoS One; 2010 Sep; 5(9):. PubMed ID: 20824055
[TBL] [Abstract][Full Text] [Related]
25. Topoisomerase II beta interacts with cohesin and CTCF at topological domain borders.
Uusküla-Reimand L; Hou H; Samavarchi-Tehrani P; Rudan MV; Liang M; Medina-Rivera A; Mohammed H; Schmidt D; Schwalie P; Young EJ; Reimand J; Hadjur S; Gingras AC; Wilson MD
Genome Biol; 2016 Aug; 17(1):182. PubMed ID: 27582050
[TBL] [Abstract][Full Text] [Related]
26. Molecular mechanisms of topoisomerase 2 DNA-protein crosslink resolution.
Riccio AA; Schellenberg MJ; Williams RS
Cell Mol Life Sci; 2020 Jan; 77(1):81-91. PubMed ID: 31728578
[TBL] [Abstract][Full Text] [Related]
27. Myeloperoxidase inhibition protects bone marrow mononuclear cells from DNA damage induced by the TOP2 poison anti-cancer drug etoposide.
Cowell IG; Austin CA
FEBS Open Bio; 2024 Jun; 14(6):1001-1010. PubMed ID: 38531625
[TBL] [Abstract][Full Text] [Related]
28. Repair of trapped topoisomerase II covalent cleavage complexes: Novel proteasome-independent mechanisms.
Tsuda M; Kitamasu K; Hosokawa S; Nakano T; Ide H
Nucleosides Nucleotides Nucleic Acids; 2020; 39(1-3):170-184. PubMed ID: 31608820
[TBL] [Abstract][Full Text] [Related]
29. [Molecular determinants of response to topoisomerase II inhibitors].
Lansiaux A; Pourquier P
Bull Cancer; 2011 Nov; 98(11):1299-310. PubMed ID: 22023806
[TBL] [Abstract][Full Text] [Related]
30. DNA double-strand breaks with 5' adducts are efficiently channeled to the DNA2-mediated resection pathway.
Tammaro M; Liao S; Beeharry N; Yan H
Nucleic Acids Res; 2016 Jan; 44(1):221-31. PubMed ID: 26420828
[TBL] [Abstract][Full Text] [Related]
31. The DNA-Binding Polyamine Moiety in the Vectorized DNA Topoisomerase II Inhibitor F14512 Alters Reparability of the Consequent Enzyme-Linked DNA Double-Strand Breaks.
Bombarde O; Larminat F; Gomez D; Frit P; Racca C; Gomes B; Guilbaud N; Calsou P
Mol Cancer Ther; 2017 Oct; 16(10):2166-2177. PubMed ID: 28611105
[TBL] [Abstract][Full Text] [Related]
32. Replication-dependent and transcription-dependent mechanisms of DNA double-strand break induction by the topoisomerase 2-targeting drug etoposide.
Tammaro M; Barr P; Ricci B; Yan H
PLoS One; 2013; 8(11):e79202. PubMed ID: 24244448
[TBL] [Abstract][Full Text] [Related]
33. Depletion of tyrosyl DNA phosphodiesterase 2 activity enhances etoposide-mediated double-strand break formation and cell killing.
Kont YS; Dutta A; Mallisetty A; Mathew J; Minas T; Kraus C; Dhopeshwarkar P; Kallakury B; Mitra S; Üren A; Adhikari S
DNA Repair (Amst); 2016 Jul; 43():38-47. PubMed ID: 27235629
[TBL] [Abstract][Full Text] [Related]
34. DNA-PK inhibition extends the therapeutic effects of Top2 poisoning to non-proliferating cells, increasing activity at a cost.
Wang T; Kyle AH; Baker JHE; Liu NA; Banáth JP; Minchinton AI
Sci Rep; 2023 Aug; 13(1):12429. PubMed ID: 37528151
[TBL] [Abstract][Full Text] [Related]
35. Proteolytic degradation of topoisomerase II (Top2) enables the processing of Top2·DNA and Top2·RNA covalent complexes by tyrosyl-DNA-phosphodiesterase 2 (TDP2).
Gao R; Schellenberg MJ; Huang SY; Abdelmalak M; Marchand C; Nitiss KC; Nitiss JL; Williams RS; Pommier Y
J Biol Chem; 2014 Jun; 289(26):17960-9. PubMed ID: 24808172
[TBL] [Abstract][Full Text] [Related]
36. TDP2 protects transcription from abortive topoisomerase activity and is required for normal neural function.
Gómez-Herreros F; Schuurs-Hoeijmakers JH; McCormack M; Greally MT; Rulten S; Romero-Granados R; Counihan TJ; Chaila E; Conroy J; Ennis S; Delanty N; Cortés-Ledesma F; de Brouwer AP; Cavalleri GL; El-Khamisy SF; de Vries BB; Caldecott KW
Nat Genet; 2014 May; 46(5):516-21. PubMed ID: 24658003
[TBL] [Abstract][Full Text] [Related]
37. Mre11 Is Essential for the Removal of Lethal Topoisomerase 2 Covalent Cleavage Complexes.
Hoa NN; Shimizu T; Zhou ZW; Wang ZQ; Deshpande RA; Paull TT; Akter S; Tsuda M; Furuta R; Tsutsui K; Takeda S; Sasanuma H
Mol Cell; 2016 Nov; 64(3):580-592. PubMed ID: 27814490
[TBL] [Abstract][Full Text] [Related]
38. Ribosomal protein S11 influences glioma response to TOP2 poisons.
Awah CU; Chen L; Bansal M; Mahajan A; Winter J; Lad M; Warnke L; Gonzalez-Buendia E; Park C; Zhang D; Feldstein E; Yu D; Zannikou M; Balyasnikova IV; Martuscello R; Konerman S; Győrffy B; Burdett KB; Scholtens DM; Stupp R; Ahmed A; Hsu P; Sonabend AM
Oncogene; 2020 Jul; 39(27):5068-5081. PubMed ID: 32528131
[TBL] [Abstract][Full Text] [Related]
39. SUMO-Targeted DNA Translocase Rrp2 Protects the Genome from Top2-Induced DNA Damage.
Wei Y; Diao LX; Lu S; Wang HT; Suo F; Dong MQ; Du LL
Mol Cell; 2017 Jun; 66(5):581-596.e6. PubMed ID: 28552615
[TBL] [Abstract][Full Text] [Related]
40. Dual functions of the homeoprotein DLX4 in modulating responsiveness of tumor cells to topoisomerase II-targeting drugs.
Trinh BQ; Ko SY; Barengo N; Lin SY; Naora H
Cancer Res; 2013 Jan; 73(2):1000-10. PubMed ID: 23222298
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]
