BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

198 related articles for article (PubMed ID: 31614771)

  • 1. Inclusion of a Furin Cleavage Site Enhances Antitumor Efficacy against Colorectal Cancer Cells of Ribotoxin α-Sarcin- or RNase T1-Based Immunotoxins.
    Ruiz-de-la-Herrán J; Tomé-Amat J; Lázaro-Gorines R; Gavilanes JG; Lacadena J
    Toxins (Basel); 2019 Oct; 11(10):. PubMed ID: 31614771
    [TBL] [Abstract][Full Text] [Related]  

  • 2. α-sarcin and RNase T1 based immunoconjugates: the role of intracellular trafficking in cytotoxic efficiency.
    Tomé-Amat J; Ruiz-de-la-Herrán J; Martínez-del-Pozo Á; Gavilanes JG; Lacadena J
    FEBS J; 2015 Feb; 282(4):673-84. PubMed ID: 25475209
    [TBL] [Abstract][Full Text] [Related]  

  • 3. A New Optimized Version of a Colorectal Cancer-Targeted Immunotoxin Based on a Non-Immunogenic Variant of the Ribotoxin α-Sarcin.
    Narbona J; Gordo RG; Tomé-Amat J; Lacadena J
    Cancers (Basel); 2023 Feb; 15(4):. PubMed ID: 36831456
    [TBL] [Abstract][Full Text] [Related]  

  • 4. A novel Carcinoembryonic Antigen (CEA)-Targeted Trimeric Immunotoxin shows significantly enhanced Antitumor Activity in Human Colorectal Cancer Xenografts.
    Lázaro-Gorines R; Ruiz-de-la-Herrán J; Navarro R; Sanz L; Álvarez-Vallina L; Martínez-Del-Pozo A; Gavilanes JG; Lacadena J
    Sci Rep; 2019 Aug; 9(1):11680. PubMed ID: 31406218
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Inclusion of a furin-sensitive spacer enhances the cytotoxicity of ribotoxin restrictocin containing recombinant single-chain immunotoxins.
    Goyal A; Batra JK
    Biochem J; 2000 Jan; 345 Pt 2(Pt 2):247-54. PubMed ID: 10620501
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Production and characterization of a colon cancer-specific immunotoxin based on the fungal ribotoxin α-sarcin.
    Carreras-Sangrà N; Tomé-Amat J; García-Ortega L; Batt CA; Oñaderra M; Martínez-del-Pozo A; Gavilanes JG; Lacadena J
    Protein Eng Des Sel; 2012 Aug; 25(8):425-35. PubMed ID: 22718791
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Overproduction of fungal ribotoxin alpha-sarcin in Escherichia coli: generation of an active immunotoxin.
    Rathore D; Nayak SK; Batra JK
    Gene; 1997 Apr; 190(1):31-5. PubMed ID: 9185846
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Preparation of an engineered safer immunotoxin against colon carcinoma based on the ribotoxin hirsutellin A.
    Tomé-Amat J; Herrero-Galán E; Oñaderra M; Martínez-Del-Pozo Á; Gavilanes JG; Lacadena J
    FEBS J; 2015 Jun; 282(11):2131-41. PubMed ID: 25752204
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Biochemical, cytotoxic and pharmacokinetic properties of an immunotoxin composed of a mouse monoclonal antibody Fib75 and the ribosome-inactivating protein alpha-sarcin from Aspergillus giganteus.
    Wawrzynczak EJ; Henry RV; Cumber AJ; Parnell GD; Derbyshire EJ; Ulbrich N
    Eur J Biochem; 1991 Feb; 196(1):203-9. PubMed ID: 2001699
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Nanobody-Based EGFR-Targeting Immunotoxins for Colorectal Cancer Treatment.
    Narbona J; Hernández-Baraza L; Gordo RG; Sanz L; Lacadena J
    Biomolecules; 2023 Jun; 13(7):. PubMed ID: 37509078
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Leucine 145 of the ribotoxin alpha-sarcin plays a key role for determining the specificity of the ribosome-inactivating activity of the protein.
    Masip M; García-Ortega L; Olmo N; García-Mayoral MF; Pérez-Cañadillas JM; Bruix M; Oñaderra M; Martínez del Pozo A; Gavilanes JG
    Protein Sci; 2003 Jan; 12(1):161-9. PubMed ID: 12493839
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The ribonucleolytic activity of the ribotoxin α-sarcin is not essential for in vitro protein biosynthesis inhibition.
    Alvarez-García E; Diago-Navarro E; Herrero-Galán E; García-Ortega L; López-Villarejo J; Olmo N; Díaz-Orejas R; Gavilanes JG; Martínez-del-Pozo A
    Biochim Biophys Acta; 2011 Oct; 1814(10):1377-82. PubMed ID: 21767671
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Purification, characterization and cytotoxicity assessment of Ageritin: The first ribotoxin from the basidiomycete mushroom Agrocybe aegerita.
    Landi N; Pacifico S; Ragucci S; Iglesias R; Piccolella S; Amici A; Di Giuseppe AMA; Di Maro A
    Biochim Biophys Acta Gen Subj; 2017 May; 1861(5 Pt A):1113-1121. PubMed ID: 28232091
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Construction and characterization of novel, recombinant immunotoxins targeting the Her2/neu oncogene product: in vitro and in vivo studies.
    Cao Y; Marks JD; Marks JW; Cheung LH; Kim S; Rosenblum MG
    Cancer Res; 2009 Dec; 69(23):8987-95. PubMed ID: 19934334
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Increasing anticarcinoma activity of an anti-erbB2 recombinant immunotoxin by the addition of an anti-EpCAM sFv.
    Stish BJ; Chen H; Shu Y; Panoskaltsis-Mortari A; Vallera DA
    Clin Cancer Res; 2007 May; 13(10):3058-67. PubMed ID: 17505009
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Efficient in vivo antitumor effect of an immunotoxin based on ribotoxin α-sarcin in nude mice bearing human colorectal cancer xenografts.
    Tomé-Amat J; Olombrada M; Ruiz-de-la-Herrán J; Pérez-Gómez E; Andradas C; Sánchez C; Martínez L; Martínez-Del-Pozo Á; Gavilanes JG; Lacadena J
    Springerplus; 2015; 4():168. PubMed ID: 25883890
    [TBL] [Abstract][Full Text] [Related]  

  • 17. [Trends in the pharmaceutical research of ribonucleases and their therapeutic uses].
    Zhang Y; Li W; Su Z
    Sheng Wu Yi Xue Gong Cheng Xue Za Zhi; 2001 Sep; 18(3):456-60. PubMed ID: 11605516
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Production and characterization of a monoclonal antibody against the ribosome inactivating protein alpha sarcin.
    Ferreri AJ; Ferraris di Celle E; Caldera M; Muñoz S; Salvarelli S; Conde F; Canevari S; Tosi E; Colnaghi MI
    Hybridoma; 1992 Aug; 11(4):437-46. PubMed ID: 1383124
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Role of histidine-50, glutamic acid-96, and histidine-137 in the ribonucleolytic mechanism of the ribotoxin alpha-sarcin.
    Lacadena J; Martínez del Pozo A; Martínez-Ruiz A; Pérez-Cañadillas JM; Bruix M; Mancheño JM; Oñaderra M; Gavilanes JG
    Proteins; 1999 Nov; 37(3):474-84. PubMed ID: 10591106
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Antifungal Activity of α-Sarcin against Penicillium digitatum: Proposal of a New Role for Fungal Ribotoxins.
    Citores L; Iglesias R; Ragucci S; Di Maro A; Ferreras JM
    ACS Chem Biol; 2018 Aug; 13(8):1978-1982. PubMed ID: 29952541
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.