These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
273 related articles for article (PubMed ID: 31620784)
1. Mutations of R882 change flanking sequence preferences of the DNA methyltransferase DNMT3A and cellular methylation patterns. Emperle M; Adam S; Kunert S; Dukatz M; Baude A; Plass C; Rathert P; Bashtrykov P; Jeltsch A Nucleic Acids Res; 2019 Dec; 47(21):11355-11367. PubMed ID: 31620784 [TBL] [Abstract][Full Text] [Related]
3. Preferential Self-interaction of DNA Methyltransferase DNMT3A Subunits Containing the R882H Cancer Mutation Leads to Dominant Changes of Flanking Sequence Preferences. Mack A; Emperle M; Schnee P; Adam S; Pleiss J; Bashtrykov P; Jeltsch A J Mol Biol; 2022 Apr; 434(7):167482. PubMed ID: 35131259 [TBL] [Abstract][Full Text] [Related]
4. Structural basis for impairment of DNA methylation by the DNMT3A R882H mutation. Anteneh H; Fang J; Song J Nat Commun; 2020 May; 11(1):2294. PubMed ID: 32385248 [TBL] [Abstract][Full Text] [Related]
5. The DNMT3A R882H mutation does not cause dominant negative effects in purified mixed DNMT3A/R882H complexes. Emperle M; Dukatz M; Kunert S; Holzer K; Rajavelu A; Jurkowska RZ; Jeltsch A Sci Rep; 2018 Sep; 8(1):13242. PubMed ID: 30185810 [TBL] [Abstract][Full Text] [Related]
6. CpG Island Hypermethylation Mediated by DNMT3A Is a Consequence of AML Progression. Spencer DH; Russler-Germain DA; Ketkar S; Helton NM; Lamprecht TL; Fulton RS; Fronick CC; O'Laughlin M; Heath SE; Shinawi M; Westervelt P; Payton JE; Wartman LD; Welch JS; Wilson RK; Walter MJ; Link DC; DiPersio JF; Ley TJ Cell; 2017 Feb; 168(5):801-816.e13. PubMed ID: 28215704 [TBL] [Abstract][Full Text] [Related]
7. Structure-guided functional suppression of AML-associated DNMT3A hotspot mutations. Lu J; Guo Y; Yin J; Chen J; Wang Y; Wang GG; Song J Nat Commun; 2024 Apr; 15(1):3111. PubMed ID: 38600075 [TBL] [Abstract][Full Text] [Related]
8. The R882H DNMT3A hot spot mutation stabilizes the formation of large DNMT3A oligomers with low DNA methyltransferase activity. Nguyen TV; Yao S; Wang Y; Rolfe A; Selvaraj A; Darman R; Ke J; Warmuth M; Smith PG; Larsen NA; Yu L; Zhu P; Fekkes P; Vaillancourt FH; Bolduc DM J Biol Chem; 2019 Nov; 294(45):16966-16977. PubMed ID: 31582562 [TBL] [Abstract][Full Text] [Related]
9. Functional Analysis of DNMT3A DNA Methyltransferase Mutations Reported in Patients with Acute Myeloid Leukemia. Khrabrova DA; Loiko AG; Tolkacheva AA; Cherepanova NA; Zvereva MI; Kirsanova OV; Gromova ES Biomolecules; 2019 Dec; 10(1):. PubMed ID: 31861499 [TBL] [Abstract][Full Text] [Related]
10. The R882H DNMT3A mutation associated with AML dominantly inhibits wild-type DNMT3A by blocking its ability to form active tetramers. Russler-Germain DA; Spencer DH; Young MA; Lamprecht TL; Miller CA; Fulton R; Meyer MR; Erdmann-Gilmore P; Townsend RR; Wilson RK; Ley TJ Cancer Cell; 2014 Apr; 25(4):442-54. PubMed ID: 24656771 [TBL] [Abstract][Full Text] [Related]
11. DNMT3A R882H mutation drives daunorubicin resistance in acute myeloid leukemia via regulating NRF2/NQO1 pathway. Chu X; Zhong L; Dan W; Wang X; Zhang Z; Liu Z; Lu Y; Shao X; Zhou Z; Chen S; Liu B Cell Commun Signal; 2022 Oct; 20(1):168. PubMed ID: 36303144 [TBL] [Abstract][Full Text] [Related]
12. The acute myeloid leukemia variant DNMT3A Arg882His is a DNMT3B-like enzyme. Norvil AB; AlAbdi L; Liu B; Tu YH; Forstoffer NE; Michie AR; Chen T; Gowher H Nucleic Acids Res; 2020 Apr; 48(7):3761-3775. PubMed ID: 32123902 [TBL] [Abstract][Full Text] [Related]
13. The R882H substitution in the human Sandoval JE; Reich NO J Biol Chem; 2019 Nov; 294(48):18207-18219. PubMed ID: 31640986 [TBL] [Abstract][Full Text] [Related]
14. Complex DNA sequence readout mechanisms of the DNMT3B DNA methyltransferase. Dukatz M; Adam S; Biswal M; Song J; Bashtrykov P; Jeltsch A Nucleic Acids Res; 2020 Nov; 48(20):11495-11509. PubMed ID: 33105482 [TBL] [Abstract][Full Text] [Related]
15. DNA methyltransferase DNMT3A forms interaction networks with the CpG site and flanking sequence elements for efficient methylation. Dukatz M; Dittrich M; Stahl E; Adam S; de Mendoza A; Bashtrykov P; Jeltsch A J Biol Chem; 2022 Oct; 298(10):102462. PubMed ID: 36067881 [TBL] [Abstract][Full Text] [Related]
17. Comprehensive structure-function characterization of DNMT3B and DNMT3A reveals distinctive de novo DNA methylation mechanisms. Gao L; Emperle M; Guo Y; Grimm SA; Ren W; Adam S; Uryu H; Zhang ZM; Chen D; Yin J; Dukatz M; Anteneh H; Jurkowska RZ; Lu J; Wang Y; Bashtrykov P; Wade PA; Wang GG; Jeltsch A; Song J Nat Commun; 2020 Jul; 11(1):3355. PubMed ID: 32620778 [TBL] [Abstract][Full Text] [Related]
18. Genetic and Epigenetic Perturbations by DNMT3A-R882 Mutants Impaired Apoptosis through Augmentation of PRDX2 in Myeloid Leukemia Cells. Bera R; Chiu MC; Huang YJ; Liang DC; Lee YS; Shih LY Neoplasia; 2018 Nov; 20(11):1106-1120. PubMed ID: 30245403 [TBL] [Abstract][Full Text] [Related]
19. CpG sites preferentially methylated by Dnmt3a in vivo. Oka M; Rodić N; Graddy J; Chang LJ; Terada N J Biol Chem; 2006 Apr; 281(15):9901-8. PubMed ID: 16439359 [TBL] [Abstract][Full Text] [Related]
20. Novel impact of the DNMT3A R882H mutation on GSH metabolism in a K562 cell model established by TALENs. Yang L; Liu Y; Zhang N; Ding X; Zhang W; Shen K; Huang L; Zhou J; Cui S; Zhu Z; Hu Z; Xiao M Oncotarget; 2017 May; 8(18):30395-30409. PubMed ID: 28418922 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]