These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

142 related articles for article (PubMed ID: 31622747)

  • 1. Regulating membrane lipid levels at the synapse by small-molecule inhibitors of monoacylglycerol lipase: new developments in therapeutic and PET imaging applications.
    Grimsey NL; Savinainen JR; Attili B; Ahamed M
    Drug Discov Today; 2020 Feb; 25(2):330-343. PubMed ID: 31622747
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Identification and Development of an Irreversible Monoacylglycerol Lipase (MAGL) Positron Emission Tomography (PET) Radioligand with High Specificity.
    Zhang L; Butler CR; Maresca KP; Takano A; Nag S; Jia Z; Arakawa R; Piro JR; Samad T; Smith DL; Nason DM; O'Neil S; McAllister L; Schildknegt K; Trapa P; McCarthy TJ; Villalobos A; Halldin C
    J Med Chem; 2019 Sep; 62(18):8532-8543. PubMed ID: 31483137
    [TBL] [Abstract][Full Text] [Related]  

  • 3. An updated patent review of monoacylglycerol lipase (MAGL) inhibitors (2018-present).
    Bononi G; Poli G; Rizzolio F; Tuccinardi T; Macchia M; Minutolo F; Granchi C
    Expert Opin Ther Pat; 2021 Feb; 31(2):153-168. PubMed ID: 33085920
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Monoacylglycerol lipase (MAGL) as a promising therapeutic target.
    Gil-Ordóñez A; Martín-Fontecha M; Ortega-Gutiérrez S; López-Rodríguez ML
    Biochem Pharmacol; 2018 Nov; 157():18-32. PubMed ID: 30059673
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Radiosynthesis and ex vivo evaluation of [(11)C-carbonyl]carbamate- and urea-based monoacylglycerol lipase inhibitors.
    Hicks JW; Parkes J; Tong J; Houle S; Vasdev N; Wilson AA
    Nucl Med Biol; 2014 Sep; 41(8):688-94. PubMed ID: 24969632
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Synthesis and preclinical evaluation of [
    Ahamed M; Attili B; van Veghel D; Ooms M; Berben P; Celen S; Koole M; Declercq L; Savinainen JR; Laitinen JT; Verbruggen A; Bormans G
    Eur J Med Chem; 2017 Aug; 136():104-113. PubMed ID: 28486208
    [TBL] [Abstract][Full Text] [Related]  

  • 7. A Novel Radiotracer for Imaging Monoacylglycerol Lipase in the Brain Using Positron Emission Tomography.
    Wang C; Placzek MS; Van de Bittner GC; Schroeder FA; Hooker JM
    ACS Chem Neurosci; 2016 Apr; 7(4):484-9. PubMed ID: 26694017
    [TBL] [Abstract][Full Text] [Related]  

  • 8. A reversible and selective inhibitor of monoacylglycerol lipase ameliorates multiple sclerosis.
    Hernández-Torres G; Cipriano M; Hedén E; Björklund E; Canales Á; Zian D; Feliú A; Mecha M; Guaza C; Fowler CJ; Ortega-Gutiérrez S; López-Rodríguez ML
    Angew Chem Int Ed Engl; 2014 Dec; 53(50):13765-70. PubMed ID: 25298214
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Design, Synthesis, and Evaluation of
    Chen Z; Mori W; Fu H; Schafroth MA; Hatori A; Shao T; Zhang G; Van RS; Zhang Y; Hu K; Fujinaga M; Wang L; Belov V; Ogasawara D; Giffenig P; Deng X; Rong J; Yu Q; Zhang X; Papisov MI; Shao Y; Collier TL; Ma JA; Cravatt BF; Josephson L; Zhang MR; Liang SH
    J Med Chem; 2019 Oct; 62(19):8866-8872. PubMed ID: 31518130
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The medicinal chemistry of agents targeting monoacylglycerol lipase.
    Viso A; Cisneros JA; Ortega-Gutiérrez S
    Curr Top Med Chem; 2008; 8(3):231-46. PubMed ID: 18289090
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Pharmacologic Characterization of JNJ-42226314, [1-(4-Fluorophenyl)indol-5-yl]-[3-[4-(thiazole-2-carbonyl)piperazin-1-yl]azetidin-1-yl]methanone, a Reversible, Selective, and Potent Monoacylglycerol Lipase Inhibitor.
    Wyatt RM; Fraser I; Welty N; Lord B; Wennerholm M; Sutton S; Ameriks MK; Dugovic C; Yun S; White A; Nguyen L; Koudriakova T; Tian G; Suarez J; Szewczuk L; Bonnette W; Ahn K; Ghosh B; Flores CM; Connolly PJ; Zhu B; Macielag MJ; Brandt MR; Chevalier K; Zhang SP; Lovenberg T; Bonaventure P
    J Pharmacol Exp Ther; 2020 Mar; 372(3):339-353. PubMed ID: 31818916
    [TBL] [Abstract][Full Text] [Related]  

  • 12. In Vitro and in Vivo Evaluation of
    Cheng R; Mori W; Ma L; Alhouayek M; Hatori A; Zhang Y; Ogasawara D; Yuan G; Chen Z; Zhang X; Shi H; Yamasaki T; Xie L; Kumata K; Fujinaga M; Nagai Y; Minamimoto T; Svensson M; Wang L; Du Y; Ondrechen MJ; Vasdev N; Cravatt BF; Fowler C; Zhang MR; Liang SH
    J Med Chem; 2018 Mar; 61(6):2278-2291. PubMed ID: 29481079
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Design, Synthesis, and Evaluation of Reversible and Irreversible Monoacylglycerol Lipase Positron Emission Tomography (PET) Tracers Using a "Tail Switching" Strategy on a Piperazinyl Azetidine Skeleton.
    Chen Z; Mori W; Deng X; Cheng R; Ogasawara D; Zhang G; Schafroth MA; Dahl K; Fu H; Hatori A; Shao T; Zhang Y; Yamasaki T; Zhang X; Rong J; Yu Q; Hu K; Fujinaga M; Xie L; Kumata K; Gou Y; Chen J; Gu S; Bao L; Wang L; Collier TL; Vasdev N; Shao Y; Ma JA; Cravatt BF; Fowler C; Josephson L; Zhang MR; Liang SH
    J Med Chem; 2019 Apr; 62(7):3336-3353. PubMed ID: 30829483
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Therapeutic potential of monoacylglycerol lipase inhibitors.
    Mulvihill MM; Nomura DK
    Life Sci; 2013 Mar; 92(8-9):492-7. PubMed ID: 23142242
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Discovery of long-chain salicylketoxime derivatives as monoacylglycerol lipase (MAGL) inhibitors.
    Bononi G; Granchi C; Lapillo M; Giannotti M; Nieri D; Fortunato S; Boustani ME; Caligiuri I; Poli G; Carlson KE; Kim SH; Macchia M; Martinelli A; Rizzolio F; Chicca A; Katzenellenbogen JA; Minutolo F; Tuccinardi T
    Eur J Med Chem; 2018 Sep; 157():817-836. PubMed ID: 30144699
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Piperazine and piperidine carboxamides and carbamates as inhibitors of fatty acid amide hydrolase (FAAH) and monoacylglycerol lipase (MAGL).
    Korhonen J; Kuusisto A; van Bruchem J; Patel JZ; Laitinen T; Navia-Paldanius D; Laitinen JT; Savinainen JR; Parkkari T; Nevalainen TJ
    Bioorg Med Chem; 2014 Dec; 22(23):6694-6705. PubMed ID: 25282655
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Discovery, synthesis and evaluation of novel reversible monoacylglycerol lipase radioligands bearing a morpholine-3-one scaffold.
    He Y; Gobbi LC; Herde AM; Rombach D; Ritter M; Kuhn B; Wittwer MB; Heer D; Hornsperger B; Bell C; O'Hara F; Benz J; Honer M; Keller C; Collin L; Richter H; Schibli R; Grether U; Mu L
    Nucl Med Biol; 2022; 108-109():24-32. PubMed ID: 35248850
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Identification of (
    He Y; Krämer SD; Grether U; Wittwer MB; Collin L; Kuhn B; Topp A; Heer D; O'Hara F; Honer M; Pavlovic A; Richter H; Ritter M; Rombach D; Keller C; Gobbi L; Mu L
    J Nucl Med; 2024 Feb; 65(2):300-305. PubMed ID: 38164615
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Comparative biochemical characterization of the monoacylglycerol lipase inhibitor KML29 in brain, spinal cord, liver, spleen, fat and muscle tissue.
    Pasquarelli N; Porazik C; Hanselmann J; Weydt P; Ferger B; Witting A
    Neuropharmacology; 2015 Apr; 91():148-56. PubMed ID: 25497453
    [TBL] [Abstract][Full Text] [Related]  

  • 20. A patent review of Monoacylglycerol Lipase (MAGL) inhibitors (2013-2017).
    Granchi C; Caligiuri I; Minutolo F; Rizzolio F; Tuccinardi T
    Expert Opin Ther Pat; 2017 Dec; 27(12):1341-1351. PubMed ID: 29053063
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.