139 related articles for article (PubMed ID: 3162572)
1. Carcinogenicity of 1-(4-amino-2-methylpyrimidine-5-yl)-methyl-3-(2-chloroethyl)-3- nitrosoureahydrochloride and three related N-nitroso derivatives following repeated intravenous administration to male Wistar rats.
Berger MR; Petru E; Schmähl D
Oncology; 1988; 45(2):127-33. PubMed ID: 3162572
[TBL] [Abstract][Full Text] [Related]
2. Examination of newly synthesized 2-chloroethylnitrosoureas in preterminal leukemia L 5222 and in two transplanted neurogenic tumors.
Berger M; Zeller WJ; Eisenbrand G; Lin PZ; Nakra M; Schmähl D
Arzneimittelforschung; 1982; 32(5):481-4. PubMed ID: 6285938
[TBL] [Abstract][Full Text] [Related]
3. Antitumor activity and toxicity of ACNU, 3-[(4-amino-2-methyl-5-pyrimidinyl)methyl]-1-(2-chloroethyl)-1-nitroso urea hydrochloride, comparing two divided doses and a single dose.
Fujimoto S; Wang Y; Ogawa M
Cancer Chemother Pharmacol; 1984; 12(3):173-8. PubMed ID: 6584235
[TBL] [Abstract][Full Text] [Related]
4. Chronic toxicity and carcinogenicity of cytostatic N-nitroso-(2-chloroethyl) ureas after repeated intravenous application to rats.
Eisenbrand G; Habs M
Dev Toxicol Environ Sci; 1980; 8():273-8. PubMed ID: 7308028
[No Abstract] [Full Text] [Related]
5. Identification of major urinary metabolites of ACNU, 3-[(4-amino-2-methyl-5-pyrimidinyl)methyl]-1-(2-chloroethyl)-1-nitroso urea hydrochloride in rats.
Nishigaki T; Nakamura K; Kinoshita T; Kuwano H; Tanaka M
J Pharmacobiodyn; 1985 Jun; 8(6):401-8. PubMed ID: 3863921
[TBL] [Abstract][Full Text] [Related]
6. Interaction of 3-[(4-amino-2-methyl-5-pyrimidinyl)methyl]-1-(2-chloroethyl)-1-nitroso urea hydrochloride with nucleic acids and proteins.
Nishigaki T; Tanaka M
Chem Biol Interact; 1985 Dec; 56(2-3):213-24. PubMed ID: 2416482
[TBL] [Abstract][Full Text] [Related]
7. Potentiation of therapeutic effects of 3-[(4-amino-2-methyl-5-pyrimidinyl)methyl]-1-(2-chloroethyl)-1-nitrosourea hydrochloride by 6-thioguanine in mouse tumor systems: comparison with other antimetabolites.
Fujimoto S; Ogawa M; Hoshino A
Gan; 1980 Feb; 71(1):60-72. PubMed ID: 6929770
[TBL] [Abstract][Full Text] [Related]
8. New experimental approaches to reducing carcinogenicity in animals by modifying regimens.
Habs M; Schmähl D
IARC Sci Publ; 1986; (78):177-85. PubMed ID: 3108155
[No Abstract] [Full Text] [Related]
9. Timing of hypertonic glucose and thermochemotherapy with 1-(4-amino-2-methylpyrimidine-5-yl) methyl-3-(2-chloroethyl)-3-nitrosourea (ACNU) in the BT4An rat glioma: relation to intratumoral pH reduction and circulatory changes after glucose supply.
Schem BC; Roszinski S; Krossnes BK; Mella O
Int J Radiat Oncol Biol Phys; 1995 Sep; 33(2):409-16. PubMed ID: 7673028
[TBL] [Abstract][Full Text] [Related]
10. Distribution, excretion, and metabolism of 3-[(4-amino-2-methyl-5-pyrimidinyl)methyl]-1-(2-chloroethyl)-1-nitrosourea (ACNU) in rats and mice after iv administration.
Tanaka M; Nishigaki T; Nakajima E; Totsuka S; Nakamura K
Cancer Treat Rep; 1980; 64(4-5):575-80. PubMed ID: 6933003
[TBL] [Abstract][Full Text] [Related]
11. Carcinogenesis and mutagenesis by N-nitroso compounds having a basic center.
Lijinsky W; Kovatch RM; Saavedra JE
Cancer Lett; 1992 Apr; 63(2):101-7. PubMed ID: 1562986
[TBL] [Abstract][Full Text] [Related]
12. Strategies of reducing the carcinogenic risk of cytostatic agents on the basis of bioassay evaluation.
Berger MR
Neoplasma; 1991; 38(4):369-78. PubMed ID: 1922569
[TBL] [Abstract][Full Text] [Related]
13. A toxicologic comparison of the potency and activity of 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU) and 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea (CCNU) in mice and rats.
Thompson GR; Larson RE
Toxicol Appl Pharmacol; 1972 Mar; 21(3):405-13. PubMed ID: 5027972
[No Abstract] [Full Text] [Related]
14. Antitumor activity and toxicity of methyl 6-[3-(2-chloroethyl)- 3-nitrosoureido]-6-deoxy-alpha-D-glucopyranoside in experimental animals.
Fujimoto S; Tashiro T; Ogawa M
Gan; 1984 Oct; 75(10):937-46. PubMed ID: 6510639
[TBL] [Abstract][Full Text] [Related]
15. Combination chemotherapy with 1-(4-amino-2-methyl-5-pyrimidinyl)methyl-3-(2-chloroethyl)-3-nitrosourea hydrochloride and bleomycin in meningeal carcinomatosis in rats.
Shimizu K; Ushio Y; Hayakawa T; Mogami H
Cancer Res; 1980 Apr; 40(4):1341-3. PubMed ID: 6153573
[TBL] [Abstract][Full Text] [Related]
16. In vitro metabolism of ACNU, 3-[(4-amino-2-methyl-5-pyrimidinyl)methyl]-1-(2-chloroethyl)-1-nitroso urea hydrochloride, a water-soluble antitumor nitrosourea.
Nishigaki T; Nakamura K; Tanaka M
J Pharmacobiodyn; 1985 Jun; 8(6):409-16. PubMed ID: 3863922
[TBL] [Abstract][Full Text] [Related]
17. Synthesis, SAR and biological evaluation of a novel series of 1-(2-chloroethyl)-1-nitroso-3-(2-(3-oxobenzoelenazol-2(3H)-yl)ethyl) urea: Organoselenium compounds for cancer therapy.
Ye S; Zheng X; Hu T; Zeng H
Cell Mol Biol (Noisy-le-grand); 2016 Jun; 62(7):6-14. PubMed ID: 27453265
[TBL] [Abstract][Full Text] [Related]
18. [Effects of phenobarbital on the metabolism of ACNU in vivo].
Nagashima T; Matsutani M; Kohono T
No To Shinkei; 1983 Jul; 35(7):677-82. PubMed ID: 6578801
[TBL] [Abstract][Full Text] [Related]
19. Biological activity of hydroxylated chloroethylnitrosoureas.
Zeller WJ; Frühauf S; Chen G; Eisenbrand G; Lijinsky W
Cancer Res; 1989 Jun; 49(12):3267-70. PubMed ID: 2720679
[TBL] [Abstract][Full Text] [Related]
20. Central nervous system toxicity and cerebrospinal fluid pharmacokinetics of intraventricular 3-[(4-amino-2-methyl-5-pyrimidinyl)ethyl]-1-(2-chloroethyl)-1-nitro soureas and other nitrosoureas in beagles.
Levin VA; Byrd D; Campbell J; Giannini DD; Borcich JK; Davis RL
Cancer Res; 1985 Aug; 45(8):3803-9. PubMed ID: 3860287
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
