BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

156 related articles for article (PubMed ID: 31630405)

  • 1. Quantitative Proteomics and Mechanistic Modeling of Transporter-Mediated Disposition in Nonalcoholic Fatty Liver Disease.
    Vildhede A; Kimoto E; Pelis RM; Rodrigues AD; Varma MVS
    Clin Pharmacol Ther; 2020 May; 107(5):1128-1137. PubMed ID: 31630405
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Transporter Expression in Liver Tissue from Subjects with Alcoholic or Hepatitis C Cirrhosis Quantified by Targeted Quantitative Proteomics.
    Wang L; Collins C; Kelly EJ; Chu X; Ray AS; Salphati L; Xiao G; Lee C; Lai Y; Liao M; Mathias A; Evers R; Humphreys W; Hop CE; Kumer SC; Unadkat JD
    Drug Metab Dispos; 2016 Nov; 44(11):1752-1758. PubMed ID: 27543206
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Pharmacokinetic Effects of Different Models of Nonalcoholic Fatty Liver Disease in Transgenic Humanized OATP1B Mice.
    Bechtold BJ; Lynch KD; Oyanna VO; Call MR; White LA; Graf TN; Oberlies NH; Clarke JD
    Drug Metab Dispos; 2024 Apr; 52(5):355-367. PubMed ID: 38485280
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Physiologically-Based Pharmacokinetic Model of Morphine and Morphine-3-Glucuronide in Nonalcoholic Steatohepatitis.
    Sjöstedt N; Neuhoff S; Brouwer KLR
    Clin Pharmacol Ther; 2021 Mar; 109(3):676-687. PubMed ID: 32897538
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Altered regulation of hepatic efflux transporters disrupts acetaminophen disposition in pediatric nonalcoholic steatohepatitis.
    Canet MJ; Merrell MD; Hardwick RN; Bataille AM; Campion SN; Ferreira DW; Xanthakos SA; Manautou JE; A-Kader HH; Erickson RP; Cherrington NJ
    Drug Metab Dispos; 2015 Jun; 43(6):829-35. PubMed ID: 25788542
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Major glucuronide metabolites of testosterone are primarily transported by MRP2 and MRP3 in human liver, intestine and kidney.
    Li CY; Basit A; Gupta A; Gáborik Z; Kis E; Prasad B
    J Steroid Biochem Mol Biol; 2019 Jul; 191():105350. PubMed ID: 30959153
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Transporter Activity Changes in Nonalcoholic Steatohepatitis: Assessment with Plasma Coproporphyrin I and III.
    Chatterjee S; Mukherjee S; Sankara Sivaprasad LVJ; Naik T; Gautam SS; Murali BV; Hadambar AA; Gunti GR; Kuchibhotla V; Deyati A; Basavanthappa S; Ramarao M; Mariappan TT; Zinker BA; Zhang Y; Sinz M; Shen H
    J Pharmacol Exp Ther; 2021 Jan; 376(1):29-39. PubMed ID: 33127749
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Population Pharmacokinetics of Morphine in Patients With Nonalcoholic Steatohepatitis (NASH) and Healthy Adults.
    Pierre V; Johnston CK; Ferslew BC; Brouwer K; Gonzalez D
    CPT Pharmacometrics Syst Pharmacol; 2017 May; 6(5):331-339. PubMed ID: 28417561
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Physiologically Based Pharmacokinetic (PBPK) Model Predictions of Disease Mediated Changes in Drug Disposition in Patients with Nonalcoholic Fatty Liver Disease (NAFLD).
    Adiwidjaja J; Spires J; Brouwer KLR
    Pharm Res; 2024 Mar; 41(3):441-462. PubMed ID: 38351228
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Protein Abundance of Clinically Relevant Drug Transporters in the Human Liver and Intestine: A Comparative Analysis in Paired Tissue Specimens.
    Drozdzik M; Busch D; Lapczuk J; Müller J; Ostrowski M; Kurzawski M; Oswald S
    Clin Pharmacol Ther; 2019 May; 105(5):1204-1212. PubMed ID: 30447067
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Altered cisplatin pharmacokinetics during nonalcoholic steatohepatitis contributes to reduced nephrotoxicity.
    Jilek JL; Frost KL; Jacobus KA; He W; Toth EL; Goedken M; Cherrington NJ
    Acta Pharm Sin B; 2021 Dec; 11(12):3869-3878. PubMed ID: 35024313
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Impaired N-linked glycosylation of uptake and efflux transporters in human non-alcoholic fatty liver disease.
    Clarke JD; Novak P; Lake AD; Hardwick RN; Cherrington NJ
    Liver Int; 2017 Jul; 37(7):1074-1081. PubMed ID: 28097795
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Mechanistic basis of altered morphine disposition in nonalcoholic steatohepatitis.
    Dzierlenga AL; Clarke JD; Hargraves TL; Ainslie GR; Vanderah TW; Paine MF; Cherrington NJ
    J Pharmacol Exp Ther; 2015 Mar; 352(3):462-70. PubMed ID: 25512370
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Interspecies variability in expression of hepatobiliary transporters across human, dog, monkey, and rat as determined by quantitative proteomics.
    Wang L; Prasad B; Salphati L; Chu X; Gupta A; Hop CE; Evers R; Unadkat JD
    Drug Metab Dispos; 2015 Mar; 43(3):367-74. PubMed ID: 25534768
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Successful Prediction of In Vivo Hepatobiliary Clearances and Hepatic Concentrations of Rosuvastatin Using Sandwich-Cultured Rat Hepatocytes, Transporter-Expressing Cell Lines, and Quantitative Proteomics.
    Ishida K; Ullah M; Tóth B; Juhasz V; Unadkat JD
    Drug Metab Dispos; 2018 Jan; 46(1):66-74. PubMed ID: 29084782
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Endogenous Coproporphyrin I and III are Altered in Multidrug Resistance-Associated Protein 2-Deficient (TR
    Bezençon J; Saran C; Hussner J; Beaudoin JJ; Zhang Y; Shen H; Fallon JK; Smith PC; Meyer Zu Schwabedissen HE; Brouwer KLR
    J Pharm Sci; 2021 Jan; 110(1):404-411. PubMed ID: 33058892
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Efflux transporter expression and acetaminophen metabolite excretion are altered in rodent models of nonalcoholic fatty liver disease.
    Lickteig AJ; Fisher CD; Augustine LM; Aleksunes LM; Besselsen DG; Slitt AL; Manautou JE; Cherrington NJ
    Drug Metab Dispos; 2007 Oct; 35(10):1970-8. PubMed ID: 17640958
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Transporter-Mediated Alterations in Patients With NASH Increase Systemic and Hepatic Exposure to an OATP and MRP2 Substrate.
    Ali I; Slizgi JR; Kaullen JD; Ivanovic M; Niemi M; Stewart PW; Barritt AS; Brouwer KLR
    Clin Pharmacol Ther; 2017 Dec; ():. PubMed ID: 29271075
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Nonalcoholic Fatty Liver Disease and Diabetes Are Associated with Decreased CYP3A4 Protein Expression and Activity in Human Liver.
    Jamwal R; de la Monte SM; Ogasawara K; Adusumalli S; Barlock BB; Akhlaghi F
    Mol Pharm; 2018 Jul; 15(7):2621-2632. PubMed ID: 29792708
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Quantification of Four Efflux Drug Transporters in Liver and Kidney Across Species Using Targeted Quantitative Proteomics by Isotope Dilution NanoLC-MS/MS.
    Fallon JK; Smith PC; Xia CQ; Kim MS
    Pharm Res; 2016 Sep; 33(9):2280-8. PubMed ID: 27356525
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.