BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

198 related articles for article (PubMed ID: 31633399)

  • 1. High-affinity sigma-1 (σ
    Niso M; Mosier PD; Marottoli R; Ferorelli S; Cassano G; Gasparre G; Leopoldo M; Berardi F; Abate C
    Future Med Chem; 2019 Oct; 11(19):2547-2562. PubMed ID: 31633399
    [No Abstract]   [Full Text] [Related]  

  • 2. Development of novel phenoxyalkylpiperidines as high-affinity Sigma-1 (σ
    Abatematteo FS; Mosier PD; Niso M; Brunetti L; Berardi F; Loiodice F; Contino M; Delprat B; Maurice T; Laghezza A; Abate C
    Eur J Med Chem; 2022 Jan; 228():114038. PubMed ID: 34902734
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Investigation of σ receptors agonist/antagonist activity through N-(6-methoxytetralin-1-yl)- and N-(6-methoxynaphthalen-1-yl)alkyl derivatives of polymethylpiperidines.
    Niso M; Abate C; Ferorelli S; Cassano G; Gasparre G; Perrone R; Berardi F
    Bioorg Med Chem; 2013 Apr; 21(7):1865-9. PubMed ID: 23415062
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The effects of new sigma (σ) receptor ligands, PB190 and PB212, in the models predictive of antidepressant activity.
    Skuza G; Sadaj W; Kabziński M; Cassano G; Gasparre G; Abate C; Berardi F
    Pharmacol Rep; 2014 Apr; 66(2):320-4. PubMed ID: 24911087
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The sigma-1 receptor antagonist PB212 reduces the Ca²⁺-release through the inositol (1, 4, 5)-trisphosphate receptor in SK-N-SH cells.
    Gasparre G; Abate C; Berardi F; Cassano G
    Eur J Pharmacol; 2012 Jun; 684(1-3):59-63. PubMed ID: 22465185
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Improving selectivity preserving affinity: new piperidine-4-carboxamide derivatives as effective sigma-1-ligands.
    Zampieri D; Laurini E; Vio L; Fermeglia M; Pricl S; Wünsch B; Schepmann D; Mamolo MG
    Eur J Med Chem; 2015 Jan; 90():797-808. PubMed ID: 25528334
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Piperidine propionamide as a scaffold for potent sigma-1 receptor antagonists and mu opioid receptor agonists for treating neuropathic pain.
    Xiong J; Jin J; Gao L; Hao C; Liu X; Liu BF; Chen Y; Zhang G
    Eur J Med Chem; 2020 Apr; 191():112144. PubMed ID: 32087465
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Pharmacophore models and development of spirocyclic ligands for σ1 receptors.
    Wunsch B
    Curr Pharm Des; 2012; 18(7):930-7. PubMed ID: 22288413
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Oxa-Pictet-Spengler reaction as key step in the synthesis of novel σ receptor ligands with 2-benzopyran structure.
    Knappmann I; Schepmann D; Wünsch B
    Bioorg Med Chem; 2016 Sep; 24(18):4045-4055. PubMed ID: 27396684
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Methyl substitution on the piperidine ring of N-[omega-(6-methoxynaphthalen-1-yl)alkyl] derivatives as a probe for selective binding and activity at the sigma(1) receptor.
    Berardi F; Ferorelli S; Abate C; Pedone MP; Colabufo NA; Contino M; Perrone R
    J Med Chem; 2005 Dec; 48(26):8237-44. PubMed ID: 16366605
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Synthesis and quantitative structure-activity relationships of N-(1-benzylpiperidin-4-yl)phenylacetamides and related analogues as potent and selective sigma1 receptor ligands.
    Huang Y; Hammond PS; Whirrett BR; Kuhner RJ; Wu L; Childers SR; Mach RH
    J Med Chem; 1998 Jun; 41(13):2361-70. PubMed ID: 9632369
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Synthesis and evaluation of a (18) F-labeled 4-phenylpiperidine-4-carbonitrile radioligand for σ1 receptor imaging.
    Ye J; Wang X; Deuther-Conrad W; Zhang J; Li J; Zhang X; Wang L; Steinbach J; Brust P; Jia H
    J Labelled Comp Radiopharm; 2016 Jul; 59(9):332-9. PubMed ID: 27277387
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Pharmacological characterization of high-affinity σ
    Schepmann D; Neue C; Westphälinger S; Müller C; Bracher F; Lange C; Bednarski P; Almansa C; Friedland K; Räbiger V; Düfer M; Wünsch B
    J Pharm Pharmacol; 2020 Feb; 72(2):236-248. PubMed ID: 31743446
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Ether modifications to 1-[2-(3,4-dimethoxyphenyl)ethyl]-4-(3-phenylpropyl)piperazine (SA4503): effects on binding affinity and selectivity for sigma receptors and monoamine transporters.
    Xu R; Lord SA; Peterson RM; Fergason-Cantrell EA; Lever JR; Lever SZ
    Bioorg Med Chem; 2015 Jan; 23(1):222-30. PubMed ID: 25468036
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Pharmacophore identification for sigma-1 (sigma1) receptor binding: application of the "deconstruction-reconstruction-elaboration" approach.
    Glennon RA
    Mini Rev Med Chem; 2005 Oct; 5(10):927-40. PubMed ID: 16250835
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Novel Sigma-1 receptor antagonists: from opioids to small molecules: what is new?
    Arena E; Dichiara M; Floresta G; Parenti C; Marrazzo A; Pittalà V; Amata E; Prezzavento O
    Future Med Chem; 2018 Jan; 10(2):231-256. PubMed ID: 29185346
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Thiazole-Based σ
    Kokornaczyk AK; Schepmann D; Yamaguchi J; Itami K; Laurini E; Fermeglia M; Pricl S; Wünsch B
    ChemMedChem; 2017 Jul; 12(13):1070-1080. PubMed ID: 28544475
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Medicinal Chemistry of σ
    Weber F; Wünsch B
    Handb Exp Pharmacol; 2017; 244():51-79. PubMed ID: 28620761
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Synthesis and binding assays of novel 3,3-dimethylpiperidine derivatives with various lipophilicities as σ₁ receptor ligands.
    Ferorelli S; Abate C; Pedone MP; Colabufo NA; Contino M; Perrone R; Berardi F
    Bioorg Med Chem; 2011 Dec; 19(24):7612-22. PubMed ID: 22075234
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Chemoenzymatic synthesis of 2,6-disubstituted tetrahydropyrans with high σ
    Kopp N; Civenni G; Marson D; Laurini E; Pricl S; Catapano CV; Humpf HU; Almansa C; Nieto FR; Schepmann D; Wünsch B
    Eur J Med Chem; 2021 Jul; 219():113443. PubMed ID: 33901806
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.