These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
199 related articles for article (PubMed ID: 31633931)
1. Phosphorylation of Histone Deacetylase 8: Structural and Mechanistic Analysis of the Phosphomimetic S39E Mutant. Welker Leng KR; Castañeda CA; Decroos C; Islam B; Haider SM; Christianson DW; Fierke CA Biochemistry; 2019 Nov; 58(45):4480-4493. PubMed ID: 31633931 [TBL] [Abstract][Full Text] [Related]
2. Active Site Metal Identity Alters Histone Deacetylase 8 Substrate Selectivity: A Potential Novel Regulatory Mechanism. Castaneda CA; Lopez JE; Joseph CG; Scholle MD; Mrksich M; Fierke CA Biochemistry; 2017 Oct; 56(42):5663-5670. PubMed ID: 28937750 [TBL] [Abstract][Full Text] [Related]
3. Structural and Functional Influence of the Glycine-Rich Loop G Porter NJ; Christianson NH; Decroos C; Christianson DW Biochemistry; 2016 Dec; 55(48):6718-6729. PubMed ID: 27933794 [TBL] [Abstract][Full Text] [Related]
4. Biochemical and structural characterization of HDAC8 mutants associated with Cornelia de Lange syndrome spectrum disorders. Decroos C; Christianson NH; Gullett LE; Bowman CM; Christianson KE; Deardorff MA; Christianson DW Biochemistry; 2015 Oct; 54(42):6501-13. PubMed ID: 26463496 [TBL] [Abstract][Full Text] [Related]
5. Loop interactions and dynamics tune the enzymatic activity of the human histone deacetylase 8. Kunze MB; Wright DW; Werbeck ND; Kirkpatrick J; Coveney PV; Hansen DF J Am Chem Soc; 2013 Nov; 135(47):17862-8. PubMed ID: 24171457 [TBL] [Abstract][Full Text] [Related]
6. HDAC8 substrate selectivity is determined by long- and short-range interactions leading to enhanced reactivity for full-length histone substrates compared with peptides. Castañeda CA; Wolfson NA; Leng KR; Kuo YM; Andrews AJ; Fierke CA J Biol Chem; 2017 Dec; 292(52):21568-21577. PubMed ID: 29109148 [TBL] [Abstract][Full Text] [Related]
7. Negative regulation of histone deacetylase 8 activity by cyclic AMP-dependent protein kinase A. Lee H; Rezai-Zadeh N; Seto E Mol Cell Biol; 2004 Jan; 24(2):765-73. PubMed ID: 14701748 [TBL] [Abstract][Full Text] [Related]
8. Substrate binding to histone deacetylases as shown by the crystal structure of the HDAC8-substrate complex. Vannini A; Volpari C; Gallinari P; Jones P; Mattu M; Carfí A; De Francesco R; Steinkühler C; Di Marco S EMBO Rep; 2007 Sep; 8(9):879-84. PubMed ID: 17721440 [TBL] [Abstract][Full Text] [Related]
9. Characterization of Histone Deacetylase 8 (HDAC8) Selective Inhibition Reveals Specific Active Site Structural and Functional Determinants. Marek M; Shaik TB; Heimburg T; Chakrabarti A; Lancelot J; Ramos-Morales E; Da Veiga C; Kalinin D; Melesina J; Robaa D; Schmidtkunz K; Suzuki T; Holl R; Ennifar E; Pierce RJ; Jung M; Sippl W; Romier C J Med Chem; 2018 Nov; 61(22):10000-10016. PubMed ID: 30347148 [TBL] [Abstract][Full Text] [Related]
10. Kinetics and thermodynamics of metal-binding to histone deacetylase 8. Kim B; Pithadia AS; Fierke CA Protein Sci; 2015 Mar; 24(3):354-65. PubMed ID: 25516458 [TBL] [Abstract][Full Text] [Related]
11. Compromised structure and function of HDAC8 mutants identified in Cornelia de Lange Syndrome spectrum disorders. Decroos C; Bowman CM; Moser JA; Christianson KE; Deardorff MA; Christianson DW ACS Chem Biol; 2014 Sep; 9(9):2157-64. PubMed ID: 25075551 [TBL] [Abstract][Full Text] [Related]
12. The activity of HDAC8 depends on local and distal sequences of its peptide substrates. Gurard-Levin ZA; Mrksich M Biochemistry; 2008 Jun; 47(23):6242-50. PubMed ID: 18470998 [TBL] [Abstract][Full Text] [Related]
13. General Base-General Acid Catalysis in Human Histone Deacetylase 8. Gantt SM; Decroos C; Lee MS; Gullett LE; Bowman CM; Christianson DW; Fierke CA Biochemistry; 2016 Feb; 55(5):820-32. PubMed ID: 26806311 [TBL] [Abstract][Full Text] [Related]
14. Structural studies of human histone deacetylase 8 and its site-specific variants complexed with substrate and inhibitors. Dowling DP; Gantt SL; Gattis SG; Fierke CA; Christianson DW Biochemistry; 2008 Dec; 47(51):13554-63. PubMed ID: 19053282 [TBL] [Abstract][Full Text] [Related]
15. Structural snapshots of human HDAC8 provide insights into the class I histone deacetylases. Somoza JR; Skene RJ; Katz BA; Mol C; Ho JD; Jennings AJ; Luong C; Arvai A; Buggy JJ; Chi E; Tang J; Sang BC; Verner E; Wynands R; Leahy EM; Dougan DR; Snell G; Navre M; Knuth MW; Swanson RV; McRee DE; Tari LW Structure; 2004 Jul; 12(7):1325-34. PubMed ID: 15242608 [TBL] [Abstract][Full Text] [Related]
16. The Importance of Structural Water in HDAC8 for Correct Binding Pose Applied for Drug Design of Anticancer Molecules. Morales-Herrejón G; Mendoza-Figueroa HL; Martínez-Archundía M; Correa-Basurto J Anticancer Agents Med Chem; 2024; 24(15):1109-1125. PubMed ID: 38835122 [TBL] [Abstract][Full Text] [Related]
17. Cloning and characterization of a novel human class I histone deacetylase that functions as a transcription repressor. Hu E; Chen Z; Fredrickson T; Zhu Y; Kirkpatrick R; Zhang GF; Johanson K; Sung CM; Liu R; Winkler J J Biol Chem; 2000 May; 275(20):15254-64. PubMed ID: 10748112 [TBL] [Abstract][Full Text] [Related]
18. Structure-Based Identification of HDAC8 Non-histone Substrates. Alam N; Zimmerman L; Wolfson NA; Joseph CG; Fierke CA; Schueler-Furman O Structure; 2016 Mar; 24(3):458-68. PubMed ID: 26933971 [TBL] [Abstract][Full Text] [Related]
19. HDAC8 Catalyzes the Hydrolysis of Long Chain Fatty Acyl Lysine. Aramsangtienchai P; Spiegelman NA; He B; Miller SP; Dai L; Zhao Y; Lin H ACS Chem Biol; 2016 Oct; 11(10):2685-2692. PubMed ID: 27459069 [TBL] [Abstract][Full Text] [Related]
20. Restoring histone deacetylase activity by waste product release. A view from molecular mechanics simulations with mammalian HDAC8. Pietra F Chem Biodivers; 2015 Apr; 12(4):503-12. PubMed ID: 25879496 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]