BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

208 related articles for article (PubMed ID: 31634469)

  • 1. H3K36me2/3 Binding and DNA Binding of the DNA Methyltransferase DNMT3A PWWP Domain Both Contribute to its Chromatin Interaction.
    Dukatz M; Holzer K; Choudalakis M; Emperle M; Lungu C; Bashtrykov P; Jeltsch A
    J Mol Biol; 2019 Dec; 431(24):5063-5074. PubMed ID: 31634469
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The Dnmt3a PWWP domain reads histone 3 lysine 36 trimethylation and guides DNA methylation.
    Dhayalan A; Rajavelu A; Rathert P; Tamas R; Jurkowska RZ; Ragozin S; Jeltsch A
    J Biol Chem; 2010 Aug; 285(34):26114-20. PubMed ID: 20547484
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The histone mark H3K36me2 recruits DNMT3A and shapes the intergenic DNA methylation landscape.
    Weinberg DN; Papillon-Cavanagh S; Chen H; Yue Y; Chen X; Rajagopalan KN; Horth C; McGuire JT; Xu X; Nikbakht H; Lemiesz AE; Marchione DM; Marunde MR; Meiners MJ; Cheek MA; Keogh MC; Bareke E; Djedid A; Harutyunyan AS; Jabado N; Garcia BA; Li H; Allis CD; Majewski J; Lu C
    Nature; 2019 Sep; 573(7773):281-286. PubMed ID: 31485078
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Structural basis for recognition of histone H3K36me3 nucleosome by human de novo DNA methyltransferases 3A and 3B.
    Rondelet G; Dal Maso T; Willems L; Wouters J
    J Struct Biol; 2016 Jun; 194(3):357-67. PubMed ID: 26993463
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The DNMT3A PWWP domain is essential for the normal DNA methylation landscape in mouse somatic cells and oocytes.
    Kibe K; Shirane K; Ohishi H; Uemura S; Toh H; Sasaki H
    PLoS Genet; 2021 May; 17(5):e1009570. PubMed ID: 34048432
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Both combinatorial K4me0-K36me3 marks on sister histone H3s of a nucleosome are required for Dnmt3a-Dnmt3L mediated de novo DNA methylation.
    Gong T; Gu X; Liu YT; Zhou Z; Zhang LL; Wen Y; Zhong WL; Xu GL; Zhou JQ
    J Genet Genomics; 2020 Feb; 47(2):105-114. PubMed ID: 32173286
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Application of dual reading domains as novel reagents in chromatin biology reveals a new H3K9me3 and H3K36me2/3 bivalent chromatin state.
    Mauser R; Kungulovski G; Keup C; Reinhardt R; Jeltsch A
    Epigenetics Chromatin; 2017 Sep; 10(1):45. PubMed ID: 28946896
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The PWWP domain of Dnmt3a and Dnmt3b is required for directing DNA methylation to the major satellite repeats at pericentric heterochromatin.
    Chen T; Tsujimoto N; Li E
    Mol Cell Biol; 2004 Oct; 24(20):9048-58. PubMed ID: 15456878
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Chromatin-dependent allosteric regulation of DNMT3A activity by MeCP2.
    Rajavelu A; Lungu C; Emperle M; Dukatz M; Bröhm A; Broche J; Hanelt I; Parsa E; Schiffers S; Karnik R; Meissner A; Carell T; Rathert P; Jurkowska RZ; Jeltsch A
    Nucleic Acids Res; 2018 Sep; 46(17):9044-9056. PubMed ID: 30102379
    [TBL] [Abstract][Full Text] [Related]  

  • 10. A DNMT3A PWWP mutation leads to methylation of bivalent chromatin and growth retardation in mice.
    Sendžikaitė G; Hanna CW; Stewart-Morgan KR; Ivanova E; Kelsey G
    Nat Commun; 2019 Apr; 10(1):1884. PubMed ID: 31015495
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Histone H3K36me2 and H3K36me3 form a chromatin platform essential for DNMT3A-dependent DNA methylation in mouse oocytes.
    Yano S; Ishiuchi T; Abe S; Namekawa SH; Huang G; Ogawa Y; Sasaki H
    Nat Commun; 2022 Aug; 13(1):4440. PubMed ID: 35922445
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Two competing mechanisms of DNMT3A recruitment regulate the dynamics of de novo DNA methylation at PRC1-targeted CpG islands.
    Weinberg DN; Rosenbaum P; Chen X; Barrows D; Horth C; Marunde MR; Popova IK; Gillespie ZB; Keogh MC; Lu C; Majewski J; Allis CD
    Nat Genet; 2021 Jun; 53(6):794-800. PubMed ID: 33986537
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Methylation of recombinant mononucleosomes by DNMT3A demonstrates efficient linker DNA methylation and a role of H3K36me3.
    Bröhm A; Schoch T; Dukatz M; Graf N; Dorscht F; Mantai E; Adam S; Bashtrykov P; Jeltsch A
    Commun Biol; 2022 Mar; 5(1):192. PubMed ID: 35236925
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Domain Structure of the Dnmt1, Dnmt3a, and Dnmt3b DNA Methyltransferases.
    Tajima S; Suetake I; Takeshita K; Nakagawa A; Kimura H; Song J
    Adv Exp Med Biol; 2022; 1389():45-68. PubMed ID: 36350506
    [TBL] [Abstract][Full Text] [Related]  

  • 15. A PWWP Domain of Histone-Lysine N-Methyltransferase NSD2 Binds to Dimethylated Lys-36 of Histone H3 and Regulates NSD2 Function at Chromatin.
    Sankaran SM; Wilkinson AW; Elias JE; Gozani O
    J Biol Chem; 2016 Apr; 291(16):8465-74. PubMed ID: 26912663
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The PWWP domain of mammalian DNA methyltransferase Dnmt3b defines a new family of DNA-binding folds.
    Qiu C; Sawada K; Zhang X; Cheng X
    Nat Struct Biol; 2002 Mar; 9(3):217-24. PubMed ID: 11836534
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Chromatin targeting of de novo DNA methyltransferases by the PWWP domain.
    Ge YZ; Pu MT; Gowher H; Wu HP; Ding JP; Jeltsch A; Xu GL
    J Biol Chem; 2004 Jun; 279(24):25447-54. PubMed ID: 14998998
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Gain-of-function DNMT3A mutations cause microcephalic dwarfism and hypermethylation of Polycomb-regulated regions.
    Heyn P; Logan CV; Fluteau A; Challis RC; Auchynnikava T; Martin CA; Marsh JA; Taglini F; Kilanowski F; Parry DA; Cormier-Daire V; Fong CT; Gibson K; Hwa V; Ibáñez L; Robertson SP; Sebastiani G; Rappsilber J; Allshire RC; Reijns MAM; Dauber A; Sproul D; Jackson AP
    Nat Genet; 2019 Jan; 51(1):96-105. PubMed ID: 30478443
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Chromatin methylation activity of Dnmt3a and Dnmt3a/3L is guided by interaction of the ADD domain with the histone H3 tail.
    Zhang Y; Jurkowska R; Soeroes S; Rajavelu A; Dhayalan A; Bock I; Rathert P; Brandt O; Reinhardt R; Fischle W; Jeltsch A
    Nucleic Acids Res; 2010 Jul; 38(13):4246-53. PubMed ID: 20223770
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Histone tails regulate DNA methylation by allosterically activating de novo methyltransferase.
    Li BZ; Huang Z; Cui QY; Song XH; Du L; Jeltsch A; Chen P; Li G; Li E; Xu GL
    Cell Res; 2011 Aug; 21(8):1172-81. PubMed ID: 21606950
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.