BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

264 related articles for article (PubMed ID: 31636395)

  • 1. Functional characterization of 84 PALB2 variants of uncertain significance.
    Wiltshire T; Ducy M; Foo TK; Hu C; Lee KY; Belur Nagaraj A; Rodrigue A; Gomes TT; Simard J; Monteiro ANA; Xia B; Carvalho MA; Masson JY; Couch FJ
    Genet Med; 2020 Mar; 22(3):622-632. PubMed ID: 31636395
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Missense PALB2 germline variant disrupts nuclear localization of PALB2 in a patient with breast cancer.
    Toh MR; Low CE; Chong ST; Chan SH; Ishak NDB; Courtney E; Kolinjivadi AM; Rodrigue A; Masson JY; Ngeow J
    Fam Cancer; 2020 Apr; 19(2):123-131. PubMed ID: 32048105
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Compromised BRCA1-PALB2 interaction is associated with breast cancer risk.
    Foo TK; Tischkowitz M; Simhadri S; Boshari T; Zayed N; Burke KA; Berman SH; Blecua P; Riaz N; Huo Y; Ding YC; Neuhausen SL; Weigelt B; Reis-Filho JS; Foulkes WD; Xia B
    Oncogene; 2017 Jul; 36(29):4161-4170. PubMed ID: 28319063
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The p.Ser64Leu and p.Pro104Leu missense variants of PALB2 identified in familial pancreatic cancer patients compromise the DNA damage response.
    Zhang Y; Park JY; Zhang F; Olson SH; Orlow I; Li Y; Kurtz RC; Ladanyi M; Chen J; Toland AE; Zhang L; Andreassen PR
    Hum Mutat; 2021 Feb; 42(2):150-163. PubMed ID: 33169439
    [TBL] [Abstract][Full Text] [Related]  

  • 5. A Validated Functional Analysis of Partner and Localizer of BRCA2 Missense Variants for Use in Clinical Variant Interpretation.
    Brnich SE; Arteaga EC; Wang Y; Tan X; Berg JS
    J Mol Diagn; 2021 Jul; 23(7):847-864. PubMed ID: 33964450
    [TBL] [Abstract][Full Text] [Related]  

  • 6. A global functional analysis of missense mutations reveals two major hotspots in the PALB2 tumor suppressor.
    Rodrigue A; Margaillan G; Torres Gomes T; Coulombe Y; Montalban G; da Costa E Silva Carvalho S; Milano L; Ducy M; De-Gregoriis G; Dellaire G; Araújo da Silva W; Monteiro AN; Carvalho MA; Simard J; Masson JY
    Nucleic Acids Res; 2019 Nov; 47(20):10662-10677. PubMed ID: 31586400
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Prevalence of BRCA1, BRCA2, and PALB2 genomic alterations among 924 Taiwanese breast cancer assays with tumor-only targeted sequencing: extended data analysis from the VGH-TAYLOR study.
    Cheng HF; Tsai YF; Liu CY; Hsu CY; Lien PJ; Lin YS; Chao TC; Lai JI; Feng CJ; Chen YJ; Chen BF; Chiu JH; Tseng LM; Huang CC
    Breast Cancer Res; 2023 Dec; 25(1):152. PubMed ID: 38098088
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Functional analysis of genetic variants in the high-risk breast cancer susceptibility gene PALB2.
    Boonen RACM; Rodrigue A; Stoepker C; Wiegant WW; Vroling B; Sharma M; Rother MB; Celosse N; Vreeswijk MPG; Couch F; Simard J; Devilee P; Masson JY; van Attikum H
    Nat Commun; 2019 Nov; 10(1):5296. PubMed ID: 31757951
    [TBL] [Abstract][Full Text] [Related]  

  • 9. BRCA1-Dependent and Independent Recruitment of PALB2-BRCA2-RAD51 in the DNA Damage Response and Cancer.
    Foo TK; Xia B
    Cancer Res; 2022 Sep; 82(18):3191-3197. PubMed ID: 35819255
    [TBL] [Abstract][Full Text] [Related]  

  • 10. BRCA1 Haploinsufficiency Is Masked by RNF168-Mediated Chromatin Ubiquitylation.
    Zong D; Adam S; Wang Y; Sasanuma H; Callén E; Murga M; Day A; Kruhlak MJ; Wong N; Munro M; Ray Chaudhuri A; Karim B; Xia B; Takeda S; Johnson N; Durocher D; Nussenzweig A
    Mol Cell; 2019 Mar; 73(6):1267-1281.e7. PubMed ID: 30704900
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Functional Categorization of
    Bouwman P; van der Heijden I; van der Gulden H; de Bruijn R; Braspenning ME; Moghadasi S; Wessels LFA; ; Vreeswijk MPG; Jonkers J
    Clin Cancer Res; 2020 Sep; 26(17):4559-4568. PubMed ID: 32546644
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Functional variant analyses (FVAs) predict pathogenicity in the BRCA1 DNA double-strand break repair pathway.
    Loke J; Pearlman A; Upadhyay K; Tesfa L; Shao Y; Ostrer H
    Hum Mol Genet; 2015 Jun; 24(11):3030-7. PubMed ID: 25652403
    [TBL] [Abstract][Full Text] [Related]  

  • 13. RNF168-mediated localization of BARD1 recruits the BRCA1-PALB2 complex to DNA damage.
    Krais JJ; Wang Y; Patel P; Basu J; Bernhardy AJ; Johnson N
    Nat Commun; 2021 Aug; 12(1):5016. PubMed ID: 34408138
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Functional Characterization of
    Boonen RACM; Vreeswijk MPG; van Attikum H
    Front Mol Biosci; 2020; 7():169. PubMed ID: 33195396
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Breast cancer-associated missense mutants of the PALB2 WD40 domain, which directly binds RAD51C, RAD51 and BRCA2, disrupt DNA repair.
    Park JY; Singh TR; Nassar N; Zhang F; Freund M; Hanenberg H; Meetei AR; Andreassen PR
    Oncogene; 2014 Oct; 33(40):4803-12. PubMed ID: 24141787
    [TBL] [Abstract][Full Text] [Related]  

  • 16. A systematic review of predicted pathogenic PALB2 variants: an analysis of mutational overlap between epithelial cancers.
    Janssen B; Bellis S; Koller T; Tischkowitz M; Liau SS
    J Hum Genet; 2020 Jan; 65(2):199-205. PubMed ID: 31619740
    [TBL] [Abstract][Full Text] [Related]  

  • 17. A BRCA1 Coiled-Coil Domain Variant Disrupting PALB2 Interaction Promotes the Development of Mammary Tumors and Confers a Targetable Defect in Homologous Recombination Repair.
    Pulver EM; Mukherjee C; van de Kamp G; Roobol SJ; Rother MB; van der Gulden H; de Bruijn R; Lattanzio MV; van der Burg E; Drenth AP; Verkaik NS; Hahn K; Klarenbeek S; de Korte-Grimmerink R; van de Ven M; Pritchard CEJ; Huijbers IJ; Xia B; van Gent DC; Essers J; van Attikum H; Ray Chaudhuri A; Bouwman P; Jonkers J
    Cancer Res; 2021 Dec; 81(24):6171-6182. PubMed ID: 34548335
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Detection of impaired homologous recombination repair in NSCLC cells and tissues.
    Birkelbach M; Ferraiolo N; Gheorghiu L; Pfäffle HN; Daly B; Ebright MI; Spencer C; O'Hara C; Whetstine JR; Benes CH; Sequist LV; Zou L; Dahm-Daphi J; Kachnic LA; Willers H
    J Thorac Oncol; 2013 Mar; 8(3):279-86. PubMed ID: 23399959
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Gene of the month: PALB2.
    Hamdan O; Nowak KM
    J Clin Pathol; 2023 Feb; 76(2):73-75. PubMed ID: 36600573
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Palb2 synergizes with Trp53 to suppress mammary tumor formation in a model of inherited breast cancer.
    Bowman-Colin C; Xia B; Bunting S; Klijn C; Drost R; Bouwman P; Fineman L; Chen X; Culhane AC; Cai H; Rodig SJ; Bronson RT; Jonkers J; Nussenzweig A; Kanellopoulou C; Livingston DM
    Proc Natl Acad Sci U S A; 2013 May; 110(21):8632-7. PubMed ID: 23657012
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.