BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

285 related articles for article (PubMed ID: 31639011)

  • 21. Differential Effects of 2-Hydroxypropyl-Cyclodextrins on Lipid Accumulation in
    Hoque S; Kondo Y; Sakata N; Yamada Y; Fukaura M; Higashi T; Motoyama K; Arima H; Higaki K; Hayashi A; Komiya T; Ishitsuka Y; Irie T
    Int J Mol Sci; 2020 Jan; 21(3):. PubMed ID: 32019132
    [TBL] [Abstract][Full Text] [Related]  

  • 22. In vitro evaluation of 2-hydroxyalkylated β-cyclodextrins as potential therapeutic agents for Niemann-Pick Type C disease.
    Kondo Y; Tokumaru H; Ishitsuka Y; Matsumoto T; Taguchi M; Motoyama K; Higashi T; Arima H; Matsuo M; Higaki K; Ohno K; Irie T
    Mol Genet Metab; 2016 Jul; 118(3):214-219. PubMed ID: 27184436
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Chronic cyclodextrin treatment of murine Niemann-Pick C disease ameliorates neuronal cholesterol and glycosphingolipid storage and disease progression.
    Davidson CD; Ali NF; Micsenyi MC; Stephney G; Renault S; Dobrenis K; Ory DS; Vanier MT; Walkley SU
    PLoS One; 2009 Sep; 4(9):e6951. PubMed ID: 19750228
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Intrathecal 2-hydroxypropyl-beta-cyclodextrin in a single patient with Niemann-Pick C1.
    Maarup TJ; Chen AH; Porter FD; Farhat NY; Ory DS; Sidhu R; Jiang X; Dickson PI
    Mol Genet Metab; 2015; 116(1-2):75-9. PubMed ID: 26189084
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Long-term efficacy of intrathecal cyclodextrin in patients with Niemann-Pick disease type C.
    Matsuo M; Sakakibara T; Sakiyama Y; So T; Kosuga M; Kakiuchi T; Ichinose F; Nakamura T; Ishitsuka Y; Irie T
    Brain Dev; 2024 May; 46(5):207-212. PubMed ID: 38448301
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Linear Cyclodextrin Polymer Prodrugs as Novel Therapeutics for Niemann-Pick Type C1 Disorder.
    Kulkarni A; Caporali P; Dolas A; Johny S; Goyal S; Dragotto J; Macone A; Jayaraman R; Fiorenza MT
    Sci Rep; 2018 Jun; 8(1):9547. PubMed ID: 29934581
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Necroptosis inhibition as a therapy for Niemann-Pick disease, type C1: Inhibition of RIP kinases and combination therapy with 2-hydroxypropyl-β-cyclodextrin.
    Cougnoux A; Clifford S; Salman A; Ng SL; Bertin J; Porter FD
    Mol Genet Metab; 2018 Dec; 125(4):345-350. PubMed ID: 30392741
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Long-Term Neuropsychological Outcomes from an Open-Label Phase I/IIa Trial of 2-Hydroxypropyl-β-Cyclodextrins (VTS-270) in Niemann-Pick Disease, Type C1.
    Farmer CA; Thurm A; Farhat N; Bianconi S; Keener LA; Porter FD
    CNS Drugs; 2019 Jul; 33(7):677-683. PubMed ID: 31187454
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Microglia activation in Niemann-Pick disease, type C1 is amendable to therapeutic intervention.
    Cougnoux A; Drummond RA; Collar AL; Iben JR; Salman A; Westgarth H; Wassif CA; Cawley NX; Farhat NY; Ozato K; Lionakis MS; Porter FD
    Hum Mol Genet; 2018 Jun; 27(12):2076-2089. PubMed ID: 29617956
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Intracerebroventricular Treatment with 2-Hydroxypropyl-β-Cyclodextrin Decreased Cerebellar and Hepatic Glycoprotein Nonmetastatic Melanoma Protein B (GPNMB) Expression in Niemann-Pick Disease Type C Model Mice.
    Fukaura M; Ishitsuka Y; Shirakawa S; Ushihama N; Yamada Y; Kondo Y; Takeo T; Nakagata N; Motoyama K; Higashi T; Arima H; Kurauchi Y; Seki T; Katsuki H; Higaki K; Matsuo M; Irie T
    Int J Mol Sci; 2021 Jan; 22(1):. PubMed ID: 33466390
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Methyl-β-cyclodextrin restores impaired autophagy flux in Niemann-Pick C1-deficient cells through activation of AMPK.
    Dai S; Dulcey AE; Hu X; Wassif CA; Porter FD; Austin CP; Ory DS; Marugan J; Zheng W
    Autophagy; 2017 Aug; 13(8):1435-1451. PubMed ID: 28613987
    [TBL] [Abstract][Full Text] [Related]  

  • 32. PEG-lipid micelles enable cholesterol efflux in Niemann-Pick Type C1 disease-based lysosomal storage disorder.
    Brown A; Patel S; Ward C; Lorenz A; Ortiz M; DuRoss A; Wieghardt F; Esch A; Otten EG; Heiser LM; Korolchuk VI; Sun C; Sarkar S; Sahay G
    Sci Rep; 2016 Aug; 6():31750. PubMed ID: 27572704
    [TBL] [Abstract][Full Text] [Related]  

  • 33. A pilot study of direct delivery of hydroxypropyl-beta-cyclodextrin to the lung by the nasal route in a mouse model of Niemann-Pick C1 disease: motor performance is unaltered and lung disease is worsened.
    Erickson RP; Deutsch G; Patil R
    J Appl Genet; 2018 May; 59(2):187-191. PubMed ID: 29411332
    [TBL] [Abstract][Full Text] [Related]  

  • 34. [Inclusion Solves Insolubility -Translational Research Cycle from Bedside to Bench and Bench to Bedside for Drug Development Targeting Niemann-Pick Disease Type C].
    Irie T
    Yakugaku Zasshi; 2022; 142(4):389-400. PubMed ID: 35370195
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Transcriptome of HPβCD-treated Niemann-Pick disease type C1 cells highlights GPNMB as a biomarker for therapeutics.
    Rodriguez-Gil JL; Baxter LL; Watkins-Chow DE; Johnson NL; Davidson CD; Carlson SR; Incao AA; ; Wallom KL; Farhat NY; Platt FM; Dale RK; Porter FD; Pavan WJ
    Hum Mol Genet; 2021 Nov; 30(24):2456-2468. PubMed ID: 34296265
    [TBL] [Abstract][Full Text] [Related]  

  • 36. The susceptibility of cochlear outer hair cells to cyclodextrin is not related to their electromotile activity.
    Zhou Y; Takahashi S; Homma K; Duan C; Zheng J; Cheatham MA; Zheng J
    Acta Neuropathol Commun; 2018 Sep; 6(1):98. PubMed ID: 30249300
    [TBL] [Abstract][Full Text] [Related]  

  • 37. LC3 Immunostaining in the Inferior Olivary Nuclei of Cats With Niemann-Pick Disease Type C1 Is Associated With Patterned Purkinje Cell Loss.
    Gurda BL; Bagel JH; Fisher SJ; Schultz ML; Lieberman AP; Hand P; Vite CH; Swain GP
    J Neuropathol Exp Neurol; 2018 Mar; 77(3):229-245. PubMed ID: 29346563
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Anesthetic management of pediatric patients with Niemann-Pick disease type C for intrathecal 2-hydroxypropyl-β-cyclodextrin injection.
    Ulloa ML; Froyshteter AB; Kret LN; Chang DP; Sarah GE; McCarthy RJ; Barnes SD; Berry-Kravis EM
    Paediatr Anaesth; 2020 Jul; 30(7):766-772. PubMed ID: 32349180
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Early experience with compassionate use of 2 hydroxypropyl-beta-cyclodextrin for Niemann-Pick type C disease: review of initial published cases.
    Megías-Vericat JE; García-Robles A; Company-Albir MJ; Fernández-Megía MJ; Pérez-Miralles FC; López-Briz E; Casanova B; Poveda JL
    Neurol Sci; 2017 May; 38(5):727-743. PubMed ID: 28155026
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Systemic administration of 2-hydroxypropyl-β-cyclodextrin to symptomatic Npc1-deficient mice slows cholesterol sequestration in the major organs and improves liver function.
    Lopez AM; Terpack SJ; Posey KS; Liu B; Ramirez CM; Turley SD
    Clin Exp Pharmacol Physiol; 2014 Oct; 41(10):780-7. PubMed ID: 25115571
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 15.