BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

388 related articles for article (PubMed ID: 31641049)

  • 1. Sphingosine Kinase 2 Potentiates Amyloid Deposition but Protects against Hippocampal Volume Loss and Demyelination in a Mouse Model of Alzheimer's Disease.
    Lei M; Teo JD; Song H; McEwen HP; Yup Lee J; Couttas TA; Duncan T; Chesworth R; Bertz J; Przybyla M; Van Eersel J; Heng B; Guillemin GJ; Ittner LM; Fath T; Garner B; Ittner A; Karl T; Don AS
    J Neurosci; 2019 Nov; 39(48):9645-9659. PubMed ID: 31641049
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Loss of the neuroprotective factor Sphingosine 1-phosphate early in Alzheimer's disease pathogenesis.
    Couttas TA; Kain N; Daniels B; Lim XY; Shepherd C; Kril J; Pickford R; Li H; Garner B; Don AS
    Acta Neuropathol Commun; 2014 Jan; 2():9. PubMed ID: 24456642
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Neuronal Protein Tyrosine Phosphatase 1B Hastens Amyloid β-Associated Alzheimer's Disease in Mice.
    Ricke KM; Cruz SA; Qin Z; Farrokhi K; Sharmin F; Zhang L; Zasloff MA; Stewart AFR; Chen HH
    J Neurosci; 2020 Feb; 40(7):1581-1593. PubMed ID: 31915254
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Wnt signaling loss accelerates the appearance of neuropathological hallmarks of Alzheimer's disease in J20-APP transgenic and wild-type mice.
    Tapia-Rojas C; Inestrosa NC
    J Neurochem; 2018 Feb; 144(4):443-465. PubMed ID: 29240990
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Bone marrow mesenchymal stem cells-derived exosomes reduce Aβ deposition and improve cognitive function recovery in mice with Alzheimer's disease by activating sphingosine kinase/sphingosine-1-phosphate signaling pathway.
    Wang X; Yang G
    Cell Biol Int; 2021 Apr; 45(4):775-784. PubMed ID: 33300254
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Conversion of Synthetic Aβ to In Vivo Active Seeds and Amyloid Plaque Formation in a Hippocampal Slice Culture Model.
    Novotny R; Langer F; Mahler J; Skodras A; Vlachos A; Wegenast-Braun BM; Kaeser SA; Neher JJ; Eisele YS; Pietrowski MJ; Nilsson KP; Deller T; Staufenbiel M; Heimrich B; Jucker M
    J Neurosci; 2016 May; 36(18):5084-93. PubMed ID: 27147660
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Glial Sphingosine-Mediated Epigenetic Regulation Stabilizes Synaptic Function in
    Yin P; Cai Y; Cui T; Berg AJ; Wang T; Morency DT; Paganelli PM; Lok C; Xue Y; Vicini S; Wang T
    J Neurosci; 2023 Oct; 43(42):6954-6971. PubMed ID: 37669862
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Reduced sphingosine kinase-1 and enhanced sphingosine 1-phosphate lyase expression demonstrate deregulated sphingosine 1-phosphate signaling in Alzheimer's disease.
    Ceccom J; Loukh N; Lauwers-Cances V; Touriol C; Nicaise Y; Gentil C; Uro-Coste E; Pitson S; Maurage CA; Duyckaerts C; Cuvillier O; Delisle MB
    Acta Neuropathol Commun; 2014 Jan; 2():12. PubMed ID: 24468113
    [TBL] [Abstract][Full Text] [Related]  

  • 9. HDAC3 negatively regulates spatial memory in a mouse model of Alzheimer's disease.
    Zhu X; Wang S; Yu L; Jin J; Ye X; Liu Y; Xu Y
    Aging Cell; 2017 Oct; 16(5):1073-1082. PubMed ID: 28771976
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Neuronal sphingosine kinase 2 subcellular localization is altered in Alzheimer's disease brain.
    Dominguez G; Maddelein ML; Pucelle M; Nicaise Y; Maurage CA; Duyckaerts C; Cuvillier O; Delisle MB
    Acta Neuropathol Commun; 2018 Apr; 6(1):25. PubMed ID: 29615132
    [TBL] [Abstract][Full Text] [Related]  

  • 11. CB2 receptor deficiency increases amyloid pathology and alters tau processing in a transgenic mouse model of Alzheimer's disease.
    Koppel J; Vingtdeux V; Marambaud P; d'Abramo C; Jimenez H; Stauber M; Friedman R; Davies P
    Mol Med; 2014 Mar; 20(1):29-36. PubMed ID: 24722782
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Complement C3 deficiency protects against neurodegeneration in aged plaque-rich APP/PS1 mice.
    Shi Q; Chowdhury S; Ma R; Le KX; Hong S; Caldarone BJ; Stevens B; Lemere CA
    Sci Transl Med; 2017 May; 9(392):. PubMed ID: 28566429
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Brain region-specific amyloid plaque-associated myelin lipid loss, APOE deposition and disruption of the myelin sheath in familial Alzheimer's disease mice.
    Kaya I; Jennische E; Lange S; Tarik Baykal A; Malmberg P; Fletcher JS
    J Neurochem; 2020 Jul; 154(1):84-98. PubMed ID: 32141089
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Aβ secretion and plaque formation depend on autophagy.
    Nilsson P; Loganathan K; Sekiguchi M; Matsuba Y; Hui K; Tsubuki S; Tanaka M; Iwata N; Saito T; Saido TC
    Cell Rep; 2013 Oct; 5(1):61-9. PubMed ID: 24095740
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Myelin dysfunction drives amyloid-β deposition in models of Alzheimer's disease.
    Depp C; Sun T; Sasmita AO; Spieth L; Berghoff SA; Nazarenko T; Overhoff K; Steixner-Kumar AA; Subramanian S; Arinrad S; Ruhwedel T; Möbius W; Göbbels S; Saher G; Werner HB; Damkou A; Zampar S; Wirths O; Thalmann M; Simons M; Saito T; Saido T; Krueger-Burg D; Kawaguchi R; Willem M; Haass C; Geschwind D; Ehrenreich H; Stassart R; Nave KA
    Nature; 2023 Jun; 618(7964):349-357. PubMed ID: 37258678
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Liraglutide and a lipidized analog of prolactin-releasing peptide show neuroprotective effects in a mouse model of β-amyloid pathology.
    Holubová M; Hrubá L; Popelová A; Bencze M; Pražienková V; Gengler S; Kratochvílová H; Haluzík M; Železná B; Kuneš J; Hölscher C; Maletínská L
    Neuropharmacology; 2019 Jan; 144():377-387. PubMed ID: 30428311
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Oligomeric amyloid-beta induces MAPK-mediated activation of brain cytosolic and calcium-independent phospholipase A
    Palavicini JP; Wang C; Chen L; Hosang K; Wang J; Tomiyama T; Mori H; Han X
    Acta Neuropathol Commun; 2017 Jul; 5(1):56. PubMed ID: 28750656
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Dysregulation of sphingosine-1-phosphate (S1P) and S1P receptor 1 signaling in the 5xFAD mouse model of Alzheimer's disease.
    Jung Y; Lopez-Benitez J; Tognoni CM; Carreras I; Dedeoglu A
    Brain Res; 2023 Jan; 1799():148171. PubMed ID: 36410428
    [TBL] [Abstract][Full Text] [Related]  

  • 19. White Matter Lipids as a Ketogenic Fuel Supply in Aging Female Brain: Implications for Alzheimer's Disease.
    Klosinski LP; Yao J; Yin F; Fonteh AN; Harrington MG; Christensen TA; Trushina E; Brinton RD
    EBioMedicine; 2015 Dec; 2(12):1888-904. PubMed ID: 26844268
    [TBL] [Abstract][Full Text] [Related]  

  • 20. CB₂ receptor deficiency increases amyloid pathology and alters tau processing in a transgenic mouse model of Alzheimer's disease.
    Koppel J; Vingtdeux V; Marambaud P; d'Abramo C; Jimenez H; Stauber M; Friedman R; Davies P
    Mol Med; 2013 Nov; 19(1):357-64. PubMed ID: 24408112
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 20.