BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

274 related articles for article (PubMed ID: 31641081)

  • 1. CD45 functions as a signaling gatekeeper in T cells.
    Courtney AH; Shvets AA; Lu W; Griffante G; Mollenauer M; Horkova V; Lo WL; Yu S; Stepanek O; Chakraborty AK; Weiss A
    Sci Signal; 2019 Oct; 12(604):. PubMed ID: 31641081
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Feedback circuits monitor and adjust basal Lck-dependent events in T cell receptor signaling.
    Schoenborn JR; Tan YX; Zhang C; Shokat KM; Weiss A
    Sci Signal; 2011 Sep; 4(190):ra59. PubMed ID: 21917715
    [TBL] [Abstract][Full Text] [Related]  

  • 3. CD45-Csk phosphatase-kinase titration uncouples basal and inducible T cell receptor signaling during thymic development.
    Zikherman J; Jenne C; Watson S; Doan K; Raschke W; Goodnow CC; Weiss A
    Immunity; 2010 Mar; 32(3):342-54. PubMed ID: 20346773
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Tyrosine 192 within the SH2 domain of the Src-protein tyrosine kinase p56
    Kästle M; Merten C; Hartig R; Kaehne T; Liaunardy-Jopeace A; Woessner NM; Schamel WW; James J; Minguet S; Simeoni L; Schraven B
    Cell Commun Signal; 2020 Nov; 18(1):183. PubMed ID: 33225946
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Phosphatase CD45 both positively and negatively regulates T cell receptor phosphorylation in reconstituted membrane protein clusters.
    Furlan G; Minowa T; Hanagata N; Kataoka-Hamai C; Kaizuka Y
    J Biol Chem; 2014 Oct; 289(41):28514-25. PubMed ID: 25128530
    [TBL] [Abstract][Full Text] [Related]  

  • 6. A weak Lck tail bite is necessary for Lck function in T cell antigen receptor signaling.
    Nika K; Tautz L; Arimura Y; Vang T; Williams S; Mustelin T
    J Biol Chem; 2007 Dec; 282(49):36000-9. PubMed ID: 17897955
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Expression of CD45 lacking the catalytic protein tyrosine phosphatase domain modulates Lck phosphorylation and T cell activation.
    Wang Y; Johnson P
    J Biol Chem; 2005 Apr; 280(14):14318-24. PubMed ID: 15687496
    [TBL] [Abstract][Full Text] [Related]  

  • 8. CD45 down-regulates Lck-mediated CD44 signaling and modulates actin rearrangement in T cells.
    Wong NK; Lai JC; Birkenhead D; Shaw AS; Johnson P
    J Immunol; 2008 Nov; 181(10):7033-43. PubMed ID: 18981123
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The differential regulation of Lck kinase phosphorylation sites by CD45 is critical for T cell receptor signaling responses.
    McNeill L; Salmond RJ; Cooper JC; Carret CK; Cassady-Cain RL; Roche-Molina M; Tandon P; Holmes N; Alexander DR
    Immunity; 2007 Sep; 27(3):425-37. PubMed ID: 17719247
    [TBL] [Abstract][Full Text] [Related]  

  • 10. CD45-associated kinase activity requires lck but not T cell receptor expression in the Jurkat T cell line.
    Koretzky GA; Kohmetscher M; Ross S
    J Biol Chem; 1993 Apr; 268(12):8958-64. PubMed ID: 8473339
    [TBL] [Abstract][Full Text] [Related]  

  • 11. A Phosphosite within the SH2 Domain of Lck Regulates Its Activation by CD45.
    Courtney AH; Amacher JF; Kadlecek TA; Mollenauer MN; Au-Yeung BB; Kuriyan J; Weiss A
    Mol Cell; 2017 Aug; 67(3):498-511.e6. PubMed ID: 28735895
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Differential effects of expression of the CD45 tyrosine protein phosphatase on the tyrosine phosphorylation of the lck, fyn, and c-src tyrosine protein kinases.
    Hurley TR; Hyman R; Sefton BM
    Mol Cell Biol; 1993 Mar; 13(3):1651-6. PubMed ID: 8441403
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Activation of the COOH-terminal Src kinase (Csk) by cAMP-dependent protein kinase inhibits signaling through the T cell receptor.
    Vang T; Torgersen KM; Sundvold V; Saxena M; Levy FO; Skålhegg BS; Hansson V; Mustelin T; Taskén K
    J Exp Med; 2001 Feb; 193(4):497-507. PubMed ID: 11181701
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The CD45 tyrosine phosphatase regulates CD3-induced signal transduction and T cell development in recombinase-deficient mice: restoration of pre-TCR function by active p56(lck).
    Pingel S; Baker M; Turner M; Holmes N; Alexander DR
    Eur J Immunol; 1999 Aug; 29(8):2376-84. PubMed ID: 10458749
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Initiation of T cell signaling by CD45 segregation at 'close contacts'.
    Chang VT; Fernandes RA; Ganzinger KA; Lee SF; Siebold C; McColl J; Jönsson P; Palayret M; Harlos K; Coles CH; Jones EY; Lui Y; Huang E; Gilbert RJC; Klenerman D; Aricescu AR; Davis SJ
    Nat Immunol; 2016 May; 17(5):574-582. PubMed ID: 26998761
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The kinase Itk and the adaptor TSAd change the specificity of the kinase Lck in T cells by promoting the phosphorylation of Tyr192.
    Granum S; Sundvold-Gjerstad V; Gopalakrishnan RP; Berge T; Koll L; Abrahamsen G; Sørlie M; Spurkland A
    Sci Signal; 2014 Dec; 7(355):ra118. PubMed ID: 25492967
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Changes in the role of the CD45 protein tyrosine phosphatase in regulating Lck tyrosine phosphorylation during thymic development.
    Falahati R; Leitenberg D
    J Immunol; 2007 Feb; 178(4):2056-64. PubMed ID: 17277109
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The role of competing mechanisms on Lck regulation.
    Bozso SJ; Kang JJH; Nagendran J
    Immunol Res; 2020 Oct; 68(5):289-295. PubMed ID: 32794043
    [TBL] [Abstract][Full Text] [Related]  

  • 19. CD44-initiated cell spreading induces Pyk2 phosphorylation, is mediated by Src family kinases, and is negatively regulated by CD45.
    Li R; Wong N; Jabali MD; Johnson P
    J Biol Chem; 2001 Aug; 276(31):28767-73. PubMed ID: 11369760
    [TBL] [Abstract][Full Text] [Related]  

  • 20. CD45 and RPTPalpha display different protein tyrosine phosphatase activities in T lymphocytes.
    Ng DH; Jabali MD; Maiti A; Borodchak P; Harder KW; Brocker T; Malissen B; Jirik FR; Johnson P
    Biochem J; 1997 Nov; 327 ( Pt 3)(Pt 3):867-76. PubMed ID: 9581568
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.