BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

229 related articles for article (PubMed ID: 31642904)

  • 21. The effect of resveratrol on beta amyloid-induced memory impairment involves inhibition of phosphodiesterase-4 related signaling.
    Wang G; Chen L; Pan X; Chen J; Wang L; Wang W; Cheng R; Wu F; Feng X; Yu Y; Zhang HT; O'Donnell JM; Xu Y
    Oncotarget; 2016 Apr; 7(14):17380-92. PubMed ID: 26980711
    [TBL] [Abstract][Full Text] [Related]  

  • 22. New insights into selective PDE4D inhibitors: 3-(Cyclopentyloxy)-4-methoxybenzaldehyde O-(2-(2,6-dimethylmorpholino)-2-oxoethyl) oxime (GEBR-7b) structural development and promising activities to restore memory impairment.
    Brullo C; Ricciarelli R; Prickaerts J; Arancio O; Massa M; Rotolo C; Romussi A; Rebosio C; Marengo B; Pronzato MA; van Hagen BTJ; van Goethem NP; D'Ursi P; Orro A; Milanesi L; Guariento S; Cichero E; Fossa P; Fedele E; Bruno O
    Eur J Med Chem; 2016 Nov; 124():82-102. PubMed ID: 27560284
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Selective SUMO modification of cAMP-specific phosphodiesterase-4D5 (PDE4D5) regulates the functional consequences of phosphorylation by PKA and ERK.
    Li X; Vadrevu S; Dunlop A; Day J; Advant N; Troeger J; Klussmann E; Jaffrey E; Hay RT; Adams DR; Houslay MD; Baillie GS
    Biochem J; 2010 Apr; 428(1):55-65. PubMed ID: 20196770
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Modulation of signaling through GPCR-cAMP-PKA pathways by PDE4 depends on stimulus intensity: Possible implications for the pathogenesis of acrodysostosis without hormone resistance.
    Motte E; Le Stunff C; Briet C; Dumaz N; Silve C
    Mol Cell Endocrinol; 2017 Feb; 442():1-11. PubMed ID: 27908835
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Inhibition of phosphodiesterase 4D suppresses mTORC1 signaling and pancreatic cancer growth.
    Jeong MH; Urquhart G; Lewis C; Chi Z; Jewell JL
    JCI Insight; 2023 Jul; 8(13):. PubMed ID: 37427586
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Influence of cell confluence on the cAMP signalling pathway in vascular smooth muscle cells.
    Belacel-Ouari M; Zhang L; Hubert F; Assaly R; Gerbier R; Jockers R; Dauphin F; Lechêne P; Fischmeister R; Manoury B; Leblais V
    Cell Signal; 2017 Jul; 35():118-128. PubMed ID: 28389413
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Ferulic acid prevents LPS-induced up-regulation of PDE4B and stimulates the cAMP/CREB signaling pathway in PC12 cells.
    Huang H; Hong Q; Tan HL; Xiao CR; Gao Y
    Acta Pharmacol Sin; 2016 Dec; 37(12):1543-1554. PubMed ID: 27665850
    [TBL] [Abstract][Full Text] [Related]  

  • 28. PDE4B5, a novel, super-short, brain-specific cAMP phosphodiesterase-4 variant whose isoform-specifying N-terminal region is identical to that of cAMP phosphodiesterase-4D6 (PDE4D6).
    Cheung YF; Kan Z; Garrett-Engele P; Gall I; Murdoch H; Baillie GS; Camargo LM; Johnson JM; Houslay MD; Castle JC
    J Pharmacol Exp Ther; 2007 Aug; 322(2):600-9. PubMed ID: 17519386
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Phosphodiesterase 4B: Master Regulator of Brain Signaling.
    Tibbo AJ; Baillie GS
    Cells; 2020 May; 9(5):. PubMed ID: 32438615
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Dysregulation of hepatic cAMP levels via altered Pde4b expression plays a critical role in alcohol-induced steatosis.
    Avila DV; Barker DF; Zhang J; McClain CJ; Barve S; Gobejishvili L
    J Pathol; 2016 Sep; 240(1):96-107. PubMed ID: 27287961
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Sub-efficacious doses of phosphodiesterase 4 and 5 inhibitors improve memory in a mouse model of Alzheimer's disease.
    Gulisano W; Tropea MR; Arancio O; Palmeri A; Puzzo D
    Neuropharmacology; 2018 Aug; 138():151-159. PubMed ID: 29885420
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Phosphodiesterases in neurodegenerative disorders.
    Bollen E; Prickaerts J
    IUBMB Life; 2012 Dec; 64(12):965-70. PubMed ID: 23129425
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Inhibition of PDE3B augments PDE4 inhibitor-induced apoptosis in a subset of patients with chronic lymphocytic leukemia.
    Moon E; Lee R; Near R; Weintraub L; Wolda S; Lerner A
    Clin Cancer Res; 2002 Feb; 8(2):589-95. PubMed ID: 11839681
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Comparison of recombinant human PDE4 isoforms: interaction with substrate and inhibitors.
    Saldou N; Obernolte R; Huber A; Baecker PA; Wilhelm R; Alvarez R; Li B; Xia L; Callan O; Su C; Jarnagin K; Shelton ER
    Cell Signal; 1998 Jun; 10(6):427-40. PubMed ID: 9720765
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Salt-Inducible Kinase 1 Terminates cAMP Signaling by an Evolutionarily Conserved Negative-Feedback Loop in β-Cells.
    Kim MJ; Park SK; Lee JH; Jung CY; Sung DJ; Park JH; Yoon YS; Park J; Park KG; Song DK; Cho H; Kim ST; Koo SH
    Diabetes; 2015 Sep; 64(9):3189-202. PubMed ID: 25918234
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Etazolate abrogates the lipopolysaccharide (LPS)-induced downregulation of the cAMP/pCREB/BDNF signaling, neuroinflammatory response and depressive-like behavior in mice.
    Guo J; Lin P; Zhao X; Zhang J; Wei X; Wang Q; Wang C
    Neuroscience; 2014 Mar; 263():1-14. PubMed ID: 24434771
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Insight into Inhibitory Mechanism of PDE4D by Dietary Polyphenols Using Molecular Dynamics Simulations and Free Energy Calculations.
    Furlan V; Bren U
    Biomolecules; 2021 Mar; 11(3):. PubMed ID: 33806914
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Heterozygous mutations in cyclic AMP phosphodiesterase-4D (PDE4D) and protein kinase A (PKA) provide new insights into the molecular pathology of acrodysostosis.
    Kaname T; Ki CS; Niikawa N; Baillie GS; Day JP; Yamamura K; Ohta T; Nishimura G; Mastuura N; Kim OH; Sohn YB; Kim HW; Cho SY; Ko AR; Lee JY; Kim HW; Ryu SH; Rhee H; Yang KS; Joo K; Lee J; Kim CH; Cho KH; Kim D; Yanagi K; Naritomi K; Yoshiura K; Kondoh T; Nii E; Tonoki H; Houslay MD; Jin DK
    Cell Signal; 2014 Nov; 26(11):2446-59. PubMed ID: 25064455
    [TBL] [Abstract][Full Text] [Related]  

  • 39. In cardiac myocytes, cAMP elevation triggers the down-regulation of transcripts and promoter activity for cyclic AMP phosphodiesterase-4A10 (PDE4A10).
    McCahill A; Campbell L; McSorley T; Sood A; Lynch MJ; Li X; Yan C; Baillie GS; Houslay MD
    Cell Signal; 2008 Nov; 20(11):2071-83. PubMed ID: 18721873
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Dimerization of cAMP phosphodiesterase-4 (PDE4) in living cells requires interfaces located in both the UCR1 and catalytic unit domains.
    Bolger GB; Dunlop AJ; Meng D; Day JP; Klussmann E; Baillie GS; Adams DR; Houslay MD
    Cell Signal; 2015 Apr; 27(4):756-69. PubMed ID: 25546709
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 12.