BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

162 related articles for article (PubMed ID: 31648792)

  • 1. Coevolutionary Couplings Unravel PAM-Proximal Constraints of CRISPR-SpCas9.
    Li Y; De la Paz JA; Jiang X; Liu R; Pokkulandra AP; Bleris L; Morcos F
    Biophys J; 2019 Nov; 117(9):1684-1691. PubMed ID: 31648792
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Rationally Designed Anti-CRISPR Nucleic Acid Inhibitors of CRISPR-Cas9.
    Barkau CL; O'Reilly D; Rohilla KJ; Damha MJ; Gagnon KT
    Nucleic Acid Ther; 2019 Jun; 29(3):136-147. PubMed ID: 30990769
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Molecular basis for the PAM expansion and fidelity enhancement of an evolved Cas9 nuclease.
    Chen W; Zhang H; Zhang Y; Wang Y; Gan J; Ji Q
    PLoS Biol; 2019 Oct; 17(10):e3000496. PubMed ID: 31603896
    [TBL] [Abstract][Full Text] [Related]  

  • 4. High-throughput analysis of the activities of xCas9, SpCas9-NG and SpCas9 at matched and mismatched target sequences in human cells.
    Kim HK; Lee S; Kim Y; Park J; Min S; Choi JW; Huang TP; Yoon S; Liu DR; Kim HH
    Nat Biomed Eng; 2020 Jan; 4(1):111-124. PubMed ID: 31937939
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Engineered dual selection for directed evolution of SpCas9 PAM specificity.
    Goldberg GW; Spencer JM; Giganti DO; Camellato BR; Agmon N; Ichikawa DM; Boeke JD; Noyes MB
    Nat Commun; 2021 Jan; 12(1):349. PubMed ID: 33441553
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Engineered CRISPR-Cas9 nucleases with altered PAM specificities.
    Kleinstiver BP; Prew MS; Tsai SQ; Topkar VV; Nguyen NT; Zheng Z; Gonzales AP; Li Z; Peterson RT; Yeh JR; Aryee MJ; Joung JK
    Nature; 2015 Jul; 523(7561):481-5. PubMed ID: 26098369
    [TBL] [Abstract][Full Text] [Related]  

  • 7. [Cas9 protein variant VQR recognizes NGAC protospacer adjacent motif in rice].
    Xin GW; Hu XX; Wang KJ; Wang XC
    Yi Chuan; 2018 Dec; 40(12):1112-1119. PubMed ID: 30559100
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Cas9 specifies functional viral targets during CRISPR-Cas adaptation.
    Heler R; Samai P; Modell JW; Weiner C; Goldberg GW; Bikard D; Marraffini LA
    Nature; 2015 Mar; 519(7542):199-202. PubMed ID: 25707807
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Genome Engineering in Rice Using Cas9 Variants that Recognize NG PAM Sequences.
    Hua K; Tao X; Han P; Wang R; Zhu JK
    Mol Plant; 2019 Jul; 12(7):1003-1014. PubMed ID: 30928636
    [TBL] [Abstract][Full Text] [Related]  

  • 10. An engineered ScCas9 with broad PAM range and high specificity and activity.
    Chatterjee P; Jakimo N; Lee J; Amrani N; Rodríguez T; Koseki SRT; Tysinger E; Qing R; Hao S; Sontheimer EJ; Jacobson J
    Nat Biotechnol; 2020 Oct; 38(10):1154-1158. PubMed ID: 32393822
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Targeted gene disruption by CRISPR/xCas9 system in Drosophila melanogaster.
    Ni XY; Zhou ZD; Huang J; Qiao X
    Arch Insect Biochem Physiol; 2020 May; 104(1):e21662. PubMed ID: 32027059
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The post-PAM interaction of RNA-guided spCas9 with DNA dictates its target binding and dissociation.
    Zhang Q; Wen F; Zhang S; Jin J; Bi L; Lu Y; Li M; Xi XG; Huang X; Shen B; Sun B
    Sci Adv; 2019 Nov; 5(11):eaaw9807. PubMed ID: 31763447
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Cas9, Cpf1 and C2c1/2/3-What's next?
    Nakade S; Yamamoto T; Sakuma T
    Bioengineered; 2017 May; 8(3):265-273. PubMed ID: 28140746
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Evolved Cas9 variants with broad PAM compatibility and high DNA specificity.
    Hu JH; Miller SM; Geurts MH; Tang W; Chen L; Sun N; Zeina CM; Gao X; Rees HA; Lin Z; Liu DR
    Nature; 2018 Apr; 556(7699):57-63. PubMed ID: 29512652
    [TBL] [Abstract][Full Text] [Related]  

  • 15. DNA targeting by Clostridium cellulolyticum CRISPR-Cas9 Type II-C system.
    Fedorova I; Arseniev A; Selkova P; Pobegalov G; Goryanin I; Vasileva A; Musharova O; Abramova M; Kazalov M; Zyubko T; Artamonova T; Artamonova D; Shmakov S; Khodorkovskii M; Severinov K
    Nucleic Acids Res; 2020 Feb; 48(4):2026-2034. PubMed ID: 31943070
    [TBL] [Abstract][Full Text] [Related]  

  • 16. CRISPR/Cas9 searches for a protospacer adjacent motif by lateral diffusion.
    Globyte V; Lee SH; Bae T; Kim JS; Joo C
    EMBO J; 2019 Feb; 38(4):. PubMed ID: 30573670
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Highly efficient base editing with expanded targeting scope using SpCas9-NG in rabbits.
    Liu Z; Shan H; Chen S; Chen M; Song Y; Lai L; Li Z
    FASEB J; 2020 Jan; 34(1):588-596. PubMed ID: 31914687
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Minimal PAM specificity of a highly similar SpCas9 ortholog.
    Chatterjee P; Jakimo N; Jacobson JM
    Sci Adv; 2018 Oct; 4(10):eaau0766. PubMed ID: 30397647
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Increasing the efficiency of CRISPR-Cas9-VQR precise genome editing in rice.
    Hu X; Meng X; Liu Q; Li J; Wang K
    Plant Biotechnol J; 2018 Jan; 16(1):292-297. PubMed ID: 28605576
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Palindromic target site identification in SARS-CoV-2, MERS-CoV and SARS-CoV-1 by adopting CRISPR-Cas technique.
    Ghosh N; Saha I; Sharma N
    Gene; 2022 Apr; 818():146136. PubMed ID: 34999179
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.