BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

334 related articles for article (PubMed ID: 31658631)

  • 1. Synthesis, Docking Studies, and In Vitro Evaluation of Some Novel Thienopyridines and Fused Thienopyridine-Quinolines as Antibacterial Agents and DNA Gyrase Inhibitors.
    Mohi El-Deen EM; Abd El-Meguid EA; Hasabelnaby S; Karam EA; Nossier ES
    Molecules; 2019 Oct; 24(20):. PubMed ID: 31658631
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Novel 1,2,4-oxadiazole-chalcone/oxime hybrids as potential antibacterial DNA gyrase inhibitors: Design, synthesis, ADMET prediction and molecular docking study.
    Ibrahim TS; Almalki AJ; Moustafa AH; Allam RM; Abuo-Rahma GEA; El Subbagh HI; Mohamed MFA
    Bioorg Chem; 2021 Jun; 111():104885. PubMed ID: 33838559
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Synthesis, antibacterial evaluation, and DNA gyrase inhibition profile of some new quinoline hybrids.
    Rizk OH; Bekhit MG; Hazzaa AAB; El-Khawass EM; Abdelwahab IA
    Arch Pharm (Weinheim); 2019 Oct; 352(10):e1900086. PubMed ID: 31389630
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Molecular docking, discovery, synthesis, and pharmacological properties of new 6-substituted-2-(3-phenoxyphenyl)-4-phenyl quinoline derivatives; an approach to developing potent DNA gyrase inhibitors/antibacterial agents.
    Alagumuthu M; Arumugam S
    Bioorg Med Chem; 2017 Feb; 25(4):1448-1455. PubMed ID: 28094220
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Discovery of New Schiff Bases Tethered Pyrazole Moiety: Design, Synthesis, Biological Evaluation, and Molecular Docking Study as Dual Targeting DHFR/DNA Gyrase Inhibitors with Immunomodulatory Activity.
    Hassan AS; Askar AA; Naglah AM; Almehizia AA; Ragab A
    Molecules; 2020 Jun; 25(11):. PubMed ID: 32498469
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Design, synthesis, and antibacterial evaluation of new quinoline-1,3,4-oxadiazole and quinoline-1,2,4-triazole hybrids as potential inhibitors of DNA gyrase and topoisomerase IV.
    Hofny HA; Mohamed MFA; Gomaa HAM; Abdel-Aziz SA; Youssif BGM; El-Koussi NA; Aboraia AS
    Bioorg Chem; 2021 Jul; 112():104920. PubMed ID: 33910078
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Design, synthesis, in vitro antimicrobial evaluation and molecular docking studies of indol-2-one tagged with morpholinosulfonyl moiety as DNA gyrase inhibitors.
    Salem MA; Ragab A; El-Khalafawy A; Makhlouf AH; Askar AA; Ammar YA
    Bioorg Chem; 2020 Mar; 96():103619. PubMed ID: 32036161
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Design of (quinolin-4-ylthio)carboxylic acids as new Escherichia coli DNA gyrase B inhibitors: machine learning studies, molecular docking, synthesis and biological testing.
    Metelytsia L; Hodyna D; Dobrodub I; Semenyuta I; Zavhorodnii M; Blagodatny V; Kovalishyn V; Brazhko O
    Comput Biol Chem; 2020 Apr; 85():107224. PubMed ID: 32018168
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Synthesis, antimicrobial evaluation, DNA gyrase inhibition, and in silico pharmacokinetic studies of novel quinoline derivatives.
    El-Shershaby MH; El-Gamal KM; Bayoumi AH; El-Adl K; Ahmed HEA; Abulkhair HS
    Arch Pharm (Weinheim); 2021 Feb; 354(2):e2000277. PubMed ID: 33078877
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Synthesis, Antimicrobial Activity and Molecular Docking of Novel Thiourea Derivatives Tagged with Thiadiazole, Imidazole and Triazine Moieties as Potential DNA Gyrase and Topoisomerase IV Inhibitors.
    Hashem HE; Amr AEE; Nossier ES; Elsayed EA; Azmy EM
    Molecules; 2020 Jun; 25(12):. PubMed ID: 32549386
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Discovery of novel multi-substituted benzo-indole pyrazole schiff base derivatives with antibacterial activity targeting DNA gyrase.
    Liu H; Chu ZW; Xia DG; Cao HQ; Lv XH
    Bioorg Chem; 2020 Jun; 99():103807. PubMed ID: 32272364
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Design, synthesis and molecular modeling studies of new series of s-triazine derivatives as antimicrobial agents against multi-drug resistant clinical isolates.
    Haiba NS; Khalil HH; Moniem MA; El-Wakil MH; Bekhit AA; Khattab SN
    Bioorg Chem; 2019 Aug; 89():103013. PubMed ID: 31174040
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Computational Approaches to Develop Isoquinoline Based Antibiotics through DNA Gyrase Inhibition Mechanisms Unveiled through Antibacterial Evaluation and Molecular Docking.
    Alagumuthu M; Muralidharan VP; Andrew M; Ahmed MH; Iyer SK; Arumugam S
    Mol Inform; 2018 Dec; 37(12):e1800048. PubMed ID: 30051592
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Design, green one-pot synthesis and molecular docking study of novel N,N-bis(cyanoacetyl)hydrazines and bis-coumarins as effective inhibitors of DNA gyrase and topoisomerase IV.
    Metwally NH; Abdallah SO; Mohsen MMA
    Bioorg Chem; 2020 Apr; 97():103672. PubMed ID: 32145481
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Synthesis, characterization, theoretical, anti-bacterial and molecular docking studies of quinoline based chalcones as a DNA gyrase inhibitor.
    Abdullah MI; Mahmood A; Madni M; Masood S; Kashif M
    Bioorg Chem; 2014 Jun; 54():31-7. PubMed ID: 24747187
    [TBL] [Abstract][Full Text] [Related]  

  • 16. New potent ciprofloxacin-uracil conjugates as DNA gyrase and topoisomerase IV inhibitors against methicillin-resistant Staphylococcus aureus.
    Samir M; Ramadan M; Abdelrahman MH; Elbastawesy MAI; Halby HM; Abdel-Aziz M; Abuo-Rahma GEA
    Bioorg Med Chem; 2022 Nov; 73():117004. PubMed ID: 36148773
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Synthesis, and antibacterial activity of novel 4,5-dihydro-1H-pyrazole derivatives as DNA gyrase inhibitors.
    Liu JJ; Sun J; Fang YB; Yang YA; Jiao RH; Zhu HL
    Org Biomol Chem; 2014 Feb; 12(6):998-1008. PubMed ID: 24382549
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Synthesis and Evaluation of N-Phenylpyrrolamides as DNA Gyrase B Inhibitors.
    Durcik M; Tammela P; Barančoková M; Tomašič T; Ilaš J; Kikelj D; Zidar N
    ChemMedChem; 2018 Jan; 13(2):186-198. PubMed ID: 29206345
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Thiazolidine-2,4-dione-linked ciprofloxacin derivatives with broad-spectrum antibacterial, MRSA and topoisomerase inhibitory activities.
    Aziz HA; El-Saghier AMM; Badr M; Abuo-Rahma GEA; Shoman ME
    Mol Divers; 2022 Jun; 26(3):1743-1759. PubMed ID: 34455532
    [TBL] [Abstract][Full Text] [Related]  

  • 20. New N-phenylpyrrolamide DNA gyrase B inhibitors: Optimization of efficacy and antibacterial activity.
    Durcik M; Lovison D; Skok Ž; Durante Cruz C; Tammela P; Tomašič T; Benedetto Tiz D; Draskovits G; Nyerges Á; Pál C; Ilaš J; Peterlin Mašič L; Kikelj D; Zidar N
    Eur J Med Chem; 2018 Jun; 154():117-132. PubMed ID: 29778894
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 17.