429 related articles for article (PubMed ID: 31661961)
1. Disclosing the Mechanism of Spontaneous Aggregation and Template-Induced Misfolding of the Key Hexapeptide (PHF6) of Tau Protein Based on Molecular Dynamics Simulation.
Liu H; Zhong H; Liu X; Zhou S; Tan S; Liu H; Yao X
ACS Chem Neurosci; 2019 Dec; 10(12):4810-4823. PubMed ID: 31661961
[TBL] [Abstract][Full Text] [Related]
2. The misfolding mechanism of the key fragment R3 of tau protein: a combined molecular dynamics simulation and Markov state model study.
Liu H; Zhong H; Xu Z; Zhang Q; Shah SJA; Liu H; Yao X
Phys Chem Chem Phys; 2020 May; 22(19):10968-10980. PubMed ID: 32392276
[TBL] [Abstract][Full Text] [Related]
3. Identification of Aggregation Mechanism of Acetylated PHF6* and PHF6 Tau Peptides Based on Molecular Dynamics Simulations and Markov State Modeling.
Shah SJA; Zhang Q; Guo J; Liu H; Liu H; Villà-Freixa J
ACS Chem Neurosci; 2023 Nov; 14(21):3959-3971. PubMed ID: 37830541
[TBL] [Abstract][Full Text] [Related]
4. Deciphering the Effect of Lysine Acetylation on the Misfolding and Aggregation of Human Tau Fragment
Shah SJA; Zhong H; Zhang Q; Liu H
Int J Mol Sci; 2022 Feb; 23(5):. PubMed ID: 35269542
[TBL] [Abstract][Full Text] [Related]
5. Atomistic Insights into the Inhibitory Mechanism of Tyrosine Phosphorylation against the Aggregation of Human Tau Fragment PHF6.
Zou Y; Guan L; Tan J; Qi B; Wang Y; Zhang Q; Sun Y
J Phys Chem B; 2023 Jan; 127(1):335-345. PubMed ID: 36594671
[TBL] [Abstract][Full Text] [Related]
6. Deciphering the Inhibitory Mechanism of Naphthoquinone-Dopamine on the Aggregation of Tau Core Fragments PHF6* and PHF6.
Zou Y; Qi B; Tan J; Guan L; Zhang Q; Sun Y; Huang F
ACS Chem Neurosci; 2023 Sep; 14(17):3265-3277. PubMed ID: 37585669
[TBL] [Abstract][Full Text] [Related]
7. Molecular dynamics simulations reveal the disruption mechanism of a 2,4-thiazolidinedione derivative C30 against tau hexapeptide (PHF6) oligomer.
Liu H; Zhong H; Liu H; Yao X
Proteins; 2022 Jan; 90(1):142-154. PubMed ID: 34331342
[TBL] [Abstract][Full Text] [Related]
8. On the Tracks of the Aggregation Mechanism of the PHF6 Peptide from Tau Protein: Molecular Dynamics, Energy, and Interaction Network Investigations.
Fagnen C; Giovannini J; Catto M; Voisin-Chiret AS; Sopkova-de Oliveira Santos J
ACS Chem Neurosci; 2022 Oct; 13(19):2874-2887. PubMed ID: 36153969
[TBL] [Abstract][Full Text] [Related]
9. Heparin remodels the microtubule-binding repeat R3 of Tau protein towards fibril-prone conformations.
Dong X; Qi R; Qiao Q; Li X; Li F; Wan J; Zhang Q; Wei G
Phys Chem Chem Phys; 2021 Sep; 23(36):20406-20418. PubMed ID: 34494046
[TBL] [Abstract][Full Text] [Related]
10. Primary Fibril Nucleation of Aggregation Prone Tau Fragments PHF6 and PHF6.
Smit FX; Luiken JA; Bolhuis PG
J Phys Chem B; 2017 Apr; 121(15):3250-3261. PubMed ID: 27776213
[TBL] [Abstract][Full Text] [Related]
11. Misfolding and Self-Assembly Dynamics of Microtubule-Binding Repeats of the Alzheimer-Related Protein Tau.
He H; Liu Y; Sun Y; Ding F
J Chem Inf Model; 2021 Jun; 61(6):2916-2925. PubMed ID: 34032430
[TBL] [Abstract][Full Text] [Related]
12. Molecular Insights into the Differential Effects of Acetylation on the Aggregation of Tau Microtubule-Binding Repeats.
Zou Y; Guan L; Tan J; Qi B; Sun Y; Huang F; Zhang Q
J Chem Inf Model; 2024 Apr; 64(8):3386-3399. PubMed ID: 38489841
[TBL] [Abstract][Full Text] [Related]
13. Deciphering the Role of ATP on PHF6 Aggregation.
Pal S; Roy R; Paul S
J Phys Chem B; 2022 Jul; 126(26):4761-4775. PubMed ID: 35759245
[TBL] [Abstract][Full Text] [Related]
14. Disclosing the Template-Induced Misfolding Mechanism of Tau Protein by Studying the Dissociation of the Boundary Chain from the Formed Tau Fibril Based on a Steered Molecular Dynamics Simulation.
Liu H; Liu X; Zhou S; An X; Liu H; Yao X
ACS Chem Neurosci; 2019 Mar; 10(3):1854-1865. PubMed ID: 30665304
[TBL] [Abstract][Full Text] [Related]
15. Computational Insights Into the Inhibition Mechanism of Proanthocyanidin B2 on Tau Hexapeptide (PHF6) Oligomer.
Li Q; Xiong C; Liu H; Ge H; Yao X; Liu H
Front Chem; 2021; 9():666043. PubMed ID: 34336783
[TBL] [Abstract][Full Text] [Related]
16. Membrane-mediated fibrillation and toxicity of the tau hexapeptide PHF6.
Fanni AM; Vander Zanden CM; Majewska PV; Majewski J; Chi EY
J Biol Chem; 2019 Oct; 294(42):15304-15317. PubMed ID: 31439664
[TBL] [Abstract][Full Text] [Related]
17. Tau assembly: the dominant role of PHF6 (VQIVYK) in microtubule binding region repeat R3.
Ganguly P; Do TD; Larini L; LaPointe NE; Sercel AJ; Shade MF; Feinstein SC; Bowers MT; Shea JE
J Phys Chem B; 2015 Apr; 119(13):4582-93. PubMed ID: 25775228
[TBL] [Abstract][Full Text] [Related]
18. Structural insights into the co-aggregation of Aβ and tau amyloid core peptides: Revealing potential pathological heterooligomers by simulations.
Li X; Chen Y; Yang Z; Zhang S; Wei G; Zhang L
Int J Biol Macromol; 2024 Jan; 254(Pt 2):127841. PubMed ID: 37924907
[TBL] [Abstract][Full Text] [Related]
19. Effects of All-Atom Molecular Mechanics Force Fields on Amyloid Peptide Assembly: The Case of PHF6 Peptide of Tau Protein.
Man VH; He X; Gao J; Wang J
J Chem Theory Comput; 2021 Oct; 17(10):6458-6471. PubMed ID: 34491058
[TBL] [Abstract][Full Text] [Related]
20. Structural transitions in tau k18 on micelle binding suggest a hierarchy in the efficacy of individual microtubule-binding repeats in filament nucleation.
Barré P; Eliezer D
Protein Sci; 2013 Aug; 22(8):1037-48. PubMed ID: 23740819
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]